- Capping Reagent A (Acetic Anhydride in THF, 1:9) is the acylating component of a two-part capping system used in automated solid-phase oligonucleotide synthesis to block unreacted hydroxyl groups.
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Acylating component (Cap A) in THF-based oligonucleotide capping systems
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Caps unreacted 5′-hydroxyl groups during solid-phase oligonucleotide synthesis
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Used in combination with a base component (Cap B) to form a two-part capping system
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Compatible with standard DNA/RNA synthesizer capping cycles
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Chemical Manufacturing
Product Information
| CAS | 108-24-7 (Acetic Anhydride) / 109-99-9 (THF) |
|---|---|
| Assay | 10% v/v Acetic Anhydride in 90% v/v THF |
| Grade | Bioreagent Grade |
| Appearance | Clear, colorless solution |
| Solubility | Fully miscible with THF and acetonitrile; moisture-sensitive |
| Molecular formula | Acetic Anhydride / THF (1:9 v/v) |
| Autoship Available | Yes |
| Pillar | High Purity |
| Water | NMT 150 ppm H₂O |
