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Arsenic is a chemical element with the symbol As and atomic number 33. Arsenic occurs in many minerals, usually in combination with sulfur and metals, but also as a pure elemental crystal. Arsenic is a metalloid. Read more here.
Arsenic trioxide is the generic name for the trade name drug Trisenox®. In some cases, health care professionals may use the trade name Trisenox® when referring to the generic drug name Arsenic Trioxide. Drug type: Arsenic Trioxide is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug.Read more here.
Arsenic trioxide is a cancer medication that interferes with the growth and spread of cancer cells in the body. Arsenic trioxide is used to treat a cancer of the blood and bone marrow called acute promyelocytic (pro-MYE-loe-SIT-ik) leukemia, or APL.Read more here.
Arsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis.Read more here.
When metallic arsenides or arsenic-containing sulfides are roasted in air, and when arsenic-containing coal is burned, arsenic trioxide is formed. The vapors condense in the flues and on the walls of the stacks as a powder commonly called “white arsenic.” Some arsenic trioxide finds its way into the air.Read more here.
Though Arsenic is well known to be a source of poisoning, many people misunderstand the common sources that put them at risk. While Arsenic is famous for being in rat poison, that is actually a very rare cause of Arsenic poisoning because very rarely is rat poisoning ingested. Read more here.
Arsenic, consumed in large amounts, can kill a person rapidly. Consumed in smaller amounts over a long period, it can cause serious illness or a prolonged death. The main cause of arsenic poisoning worldwide is the drinking of groundwater that contains high levels of the toxin.Read more here.
Long-term exposure to arsenic in drinking water can cause cancer in the skin, lungs, bladder and kidney. It can also cause other skin changes such as thickening and pigmentation. Exposure to arsenic in the workplace by inhalation can also cause lung cancer.Read more here.
Arsenic trioxide (ATO) is very potent as a single agent against acute promyelocytic leukemia (APL). It is useful in new cases of relapsed APL and has been used as a remission inducer or in the consolidation phase of treatment for APL.Read more here.
Our previous work found that the arsenic trioxide, clinically approved for treating acute promyelocytic leukemia,could efficiently reactivate latent provirus in CD4+T cells from HIV-1 patients and Simian immunodeficiency virus (SIV)-infected macaques, without significant systemic T cell activation and inflammatory responses. In this study, we are going to study the safety of and efficacy of arsenic trioxide combined with cART in 20 HIV-1 infected patients, by observing adverse events,HIV-1 reservoir, HIV-1 load, and some immune index.Read more here.
Arsenic Trioxide. Arsenic trioxide is the generic name for the trade name drug Trisenox®. In some cases, health care professionals may use the trade name Trisenox® when referring to the generic drug name Arsenic Trioxide. Drug type: Arsenic Trioxide is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug.Read more here.
The mechanism of action of Arsenic Trioxide is not completely understood. Arsenic trioxide causes morphological changes and DNA fragmentation characteristic of apoptosis in NB4 human promyelocytic leukemia cells in vitro. Arsenic trioxide also causes damage or degradation of the fusion protein PML/RAR-alpha.Read more here.
Arsenic trioxide, sold under the brand name Trisenox among others, is an inorganic compound and medication. As an industrial chemical major uses include in the manufacture of wood preservatives, pesticides, and glass. As a medication it is used to treat a type of cancer known as acute promyelocytic leukemia. For this use it is given by injection into a vein. Common side effects include vomiting, diarrhea, swelling, shortness of breath, and headaches. Severe side effects may include APL differentiation syndrome and heart problems. Use during pregnancy or breastfeeding may harm the baby. Arsenic trioxide has the formula As2O3. How it works in cancer is not entirely clear. Arsenic trioxide was approved for medical use in the United States in 2000. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. Approximately 50,000 tonnes are produced a year. In the United Kingdom it costs the NHS £292 a dose as of 2018. In the United States this amount costs about US$508 as of 2019. Due to its toxicity a number of countries have regulations around its manufacture and sale.Read more here.
Purification of synthesis gas. Primary material for all arsenic cmpd; for preserving hides; textile mordant. Glass raw material. Nokes froth flotation reagent component. Pigments; ceramic enamels; aniline colors; decolorizing agent in glass; sheep and cattle dip; hide preservative; wood preservative; preparation of other arsenic compounds. Chemical intermediate; herbicide; insecticide; rodenticide. Chemical intermediate for arsenical insecticides such as calcium arsenate. Chemical intermediate for organic arsenical herbicides and fungicides. Component of wood preservatives. Reagent in mineral flotation. Decolorizing and refining agent in glass manufacturing. Chemical intermediate for arsenic sulfides. Raw material for production of arsenic metal. Chemical intermediate for organic arsenical pharmaceuticals. Chemical intermediate for arsanilic acid (feed additive). Medicine for veterinarians and humans.Read more here.
How Do You Dissolve Arsenic Trioxide?
It is practically insoluble in water, inethanol (95)and indiethyl ether. It dissolves insodium hydroxideTS. Identification Dissolve 0.2 g of Arsenic Trioxide in 40 mL of water by heating on a water bath; the solution responds to the Qualitative Tests for arsenite.Read more here.