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Methyl Salicylate Product Summary
Methyl salicylate is an organic compound with the formula C₆H₄. Medical Grade Methyl Salicylate is ordered online at LabAlley.com for medicinal uses and to make personal care products. It is the methyl ester of salicylic acid. It is used extensively in the United States to make topical pain relief products. It is a colorless, viscous liquid with a sweet fruity odor reminiscent of root beer. The odor is often described as "minty" due to its use in mint candies.
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- Also Called Oil of Wintergreen
- Use Methyl Salicylate For Topical Ointments And Toothpaste
- Use Methyl Salicylate To Treat Joint And Muscular Pain
- Methyl Salicylate Is Used As A Local Anesthetic
- Methyl Salicylate Is Used As A Denaturant, Pesticide And Fragrance Ingredient
- Methyl Salicylate Purchased Online At LabAlley.com Is Blended With Methanol To Make Antirheumatic Ointments, Muscle Creams, Topical Ointments, Pain Relief Creams And Patches
- Methyl Salicylate Is Blended With Piroxicam, Menthol and Capsaicin To Make Topical Gels
- Methyl Salicylate Is Used In Perfumes And Toothpaste
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- Methyl Salicylate Is The Methyl Ester Of Salicylic Acid
High Purity Methyl Salicylate Purchased At LabAlley.com Is The Synthetic Form
- CAS Registry Number For Methyl Salicylate Is 119-36-8
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- Reference Standard Synonym(s): 2-Hydroxybenzoic acid methyl ester; Methyl 2-hydroxybenzoate; Oil of wintergreen; Wintergreen Oil
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- Uses And Side Effects Of Methyl Salicylate Topical Patches From WebMD
- Molar mass: 152.1494 g/mol
- Formula: C8H8O3
- Acidity (pKa): 9.8
- Solubility in water: 0.639 g/L (21 °C); 0.697 g/L (30 °C)
- Solubility: Miscible in organic solvents
- Solubility in acetone: 10.1 g/g (30 °C)
- Autoignition temperature: 452.7 °C (846.9 °F; 725.8 K)
Methyl Salicylate | Synthetic Form | Product Specifications:
Methyl salicylate is used in high concentrations as a rubefacient and analgesic in deep heating liniments (such as Bengay) to treat joint and muscular pain. Randomised double blind trials report that evidence of its effectiveness is weak, but stronger for acute pain than chronic pain, and that effectiveness may be due entirely to counterirritation. However, in the body it metabolizes into salicylates, including salicylic acid, a known NSAID.
Methyl salicylate is used in low concentrations (0.04% and under) as a flavoring agent in chewing gum and mints. When mixed with sugar and dried it is a potentially entertaining source of triboluminescence, gaining the tendency to build up electrical charge when crushed or rubbed. This effect can be observed by crushing wintergreen Life Savers in a dark room. It is used as an antiseptic in Listerine mouthwash produced by the Johnson & Johnson company. It provides fragrance to various products and as an odor-masking agent for some organophosphate pesticides.
Methyl salicylate is also used as a bait for attracting male orchid bees for study, which apparently gather the chemical to synthesize pheromones, and to clear plant or animal tissue samples of color, and as such is useful for microscopy and immunohistochemistry when excess pigments obscure structures or block light in the tissue being examined. This clearing generally only takes a few minutes, but the tissue must first be dehydrated in alcohol.
Additional applications include used as a simulant or surrogate for the research of chemical warfare agent sulfur mustard, due to its similar chemical and physical properties, in restoring (at least temporarily) the elastomeric properties of old rubber rollers, especially in printers, and as a penetrating oil to loosen rusted parts.
Methyl salicylate is potentially deadly, especially for young children. A single teaspoon (5 ml) of methyl salicylate contains approximately 6 g of salicylate, which is equivalent to almost twenty 300 mg aspirin tablets (5 mL × 1.174 g/mL = 5.87 g). Toxic ingestions of salicylates typically occur with doses of approximately 150 mg/kg body weight. This can be achieved with 1 ml of oil of wintergreen, which equates to 140 mg/kg of salicylates for a 10 kg child (22 lbs). The lowest published lethal dose is 101 mg/kg body weight in adult humans, (or 7.07 grams for a 70 kg adult). It has proven fatal to small children in doses as small as 4 ml. A seventeen-year-old cross-country runner at Notre Dame Academy on Staten Island died in April 2007 after her body absorbed methyl salicylate through excessive use of topical muscle-pain relief products.
Most instances of human toxicity due to methyl salicylate are a result of over-application of topical analgesics, especially involving children. Salicylate, the major metabolite of methyl salicylate, may be quantitated in blood, plasma or serum to confirm a diagnosis of poisoning in hospitalized patients or to assist in an autopsy.
Methyl salicylate is a benzoate ester that is the methyl ester of salicylic acid. It has a role as a flavouring agent, a metabolite and an insect attractant. It is a benzoate ester and a member of salicylates. It derives from a salicylic acid.
Methyl salicylate appears as colorless yellowish or reddish liquid with odor of wintergreen. Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. The compound was first extracted and isolated from plant species Gaultheria procumbens in 1843. It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and liniments. It forms a colorless to yellow or reddish liquid and exhibits a characteristic odor and taste of wintergreen. For acute joint and muscular pain, methyl salicylate is used as a rubefacient and analgesic in deep heating liniments. It is used as a flavoring agent in chewing gums and mints in small concentrations and added as antiseptic in mouthwash solutions.
Safety And Hazards Information For Methyl Salicylate From PubChem
Harmful if swallowed, inhaled, absorbed through skin. Vapor mist is irritating to the eyes, mucous membranes, upper respiratory tract and skin. Ingestion of relatively small amount causes severe poisoning and death. Causes nausea, vomiting, acidosis, pulmonary edema, pneumonia, convulsions and death.