Triton X-405 Surfactant

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Why Buy Triton X-405 Surfactant from Lab Alley

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Octoxinol, Octoxynol-1, Octoxynol-3, Triton X, 2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethanol, 4-tert-Octylphenol Monoethoxylate Ethanol
Triton X-405

Triton X-405 has hemolytic property and is used for DNA extraction. Triton™ X-405 is a common non-ionic surfactant and emulsifier which is often used in biochemical applications to solubilize proteins. It is considered a comparatively mild detergent, non-denaturing, and is reported in numerous references as a routinely added reagent. It is utilized for lysing cells to extract protein and cellular organelles. It can also permeabilize the living cell membrane for transfection.


Triton X-405 Features:

Solids 70.6%
pH (1% in 6H20+10IPA) 8
Color Pt-Co 15
  • In the permeabilization of cells for immunofluorescence staining
  • As a component of lysis buffer in western blot analysis
  • As a component of Tris-buffered saline for the preparation of cell sections in Immunogold labelling for electron microscope

Triton X-405 is a commonly used detergent in laboratories.[5] Triton X-405is widely used to lyse cells to extract protein or organelles, or to permeabilize the membranes of living cells.

Some applications include:

  • Inactivation of lipid-enveloped viruses (e.g. HIV, HBV, HCV) in manufacturing of biopharmaceuticals
  • Industrial purpose (plating of metal)
  • Ingredient in influenza vaccines, including Fluzone
  • Permeabilizing unfixed (or lightly fixed) eukaryotic cell membranes
  • Solubilizing membrane proteins in their native state in conjunction with zwitterionic detergents such as CHAPS
  • Part of the lysis buffer (usually in a 5% solution in alkaline lysis buffer) in DNA extraction
  • Reducing surface tension of aqueous solutions during immunostaining (usually at a concentration of 0.1-0.5% in TBS or PBS Buffer)
  • Dispersion of carbon materials for soft composite materials
  • Restricting colony expansion in Aspergillus nidulans in microbiology
  • Decellularization of animal-derived tissues
  • Removing SDS from SDS-PAGE gels prior to renaturing the proteins within the gel
  • Disruption of cell monolayers as a positive control for TEER measurements
  • Micellar catalyst
Safety and Handling

Triton X-405 SDS: Contact Lab Alley to request the Safety Data Sheet for Triton X-405.


Download Safety Data Sheet (SDS) Download Product Specification Sheet