- Capping Reagent A (Acetic Anhydride, 2,6-Lutidine in THF, 1:1:8) is a pre-mixed single-bottle capping solution combining an acylating agent with a hindered base for automated oligonucleotide synthesis with reduced side reactions.
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Single-bottle capping A reagent combining acylating agent and base for simplified synthesis setup
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Caps unreacted 5′-hydroxyl groups during automated oligonucleotide synthesis
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2,6-Lutidine base minimizes side reactions compared to pyridine-based formulations
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Compatible with standard phosphoramidite DNA/RNA synthesizer protocols
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Chemical Manufacturing
Product Information
| CAS | 108-24-7 / 108-48-5 / 109-99-9 |
|---|---|
| Assay | 10% v/v Acetic Anhydride, 10% v/v 2,6-Lutidine in 80% v/v THF |
| Grade | Bioreagent Grade |
| Appearance | Clear, colorless solution |
| Solubility | Fully miscible with THF; moisture-sensitive |
| Autoship Available | Yes |
| Pillar | High Purity |
| Water | NMT 150 ppm H₂O |
