- Capping Reagent B (Acetic Anhydride in Acetonitrile, 1:9) is the acylating component of an acetonitrile-based capping system for automated solid-phase oligonucleotide synthesis on platforms using acetonitrile reagent lines.
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Acylating Cap B reagent in acetonitrile-based capping systems for oligonucleotide synthesis
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Used on synthesizer platforms that use acetonitrile as the capping solvent instead of THF
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Caps unreacted hydroxyl groups during standard phosphoramidite synthesis cycles
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Compatible with RNA synthesis protocols requiring acetonitrile-based reagent lines
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Chemical Manufacturing
Product Information
| CAS | 108-24-7 (Ac₂O) / 75-05-8 (MeCN) |
|---|---|
| Assay | 10% v/v Acetic Anhydride in 90%v/v Acetonitrile |
| Grade | Bioreagent Grade |
| Appearance | Clear, colorless solution |
| Solubility | Fully miscible with acetonitrile; moisture-sensitive |
| Autoship Available | Yes |
| Pillar | High Purity |
| Water | NMT 150 ppm H₂O |
