Witch Hazel Safety & Hazards

Witch hazel is widely regarded as a gentle and natural skincare ingredient, frequently found in toners, medicated wipes, and over-the-counter ointments. While its soothing and anti-inflammatory benefits are well documented, it's still important to understand its chemical profile and safety considerations, especially when used in concentrated or alcohol-based forms.

Is witch hazel safe? In most cases, yes. When used as directed, it poses minimal risk and is generally classified as non-hazardous. However, certain preparations, particularly those with alcohol, may require extra care. Potential hazards include mild irritation to the eyes or skin, respiratory discomfort when aerosolized, and flammability in alcohol-containing solutions.

This article offers a comprehensive overview of witch hazel’s potential risks, exposure effects, safe handling, and compliance requirements in workplaces, labs, and homes. Let’s begin by outlining the essential chemical hazard classifications associated with witch hazel.
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In this article, we’ll review:

1. Chemical Hazards Overview

2. Exposure Risks & Health Effects

3. First Aid Measures

4. Handling & Storage Precautions

5. Spill & Leak Procedures

6. Fire & Explosion Hazards

7. Regulatory & Compliance Information

Chemical Hazards Overview

Witch hazel is generally regarded as non-hazardous under most regulatory frameworks, particularly in its water-based or diluted forms. However, alcohol-based witch hazel preparations can introduce mild chemical hazards that require proper labeling and precautions.

Understanding how witch hazel is classified by global and national standards is essential for anyone handling it in bulk or professional environments.

Hazard Classification

GHS Classification: Most witch hazel extracts do not require a hazard classification under the Globally Harmonized System (GHS). However, if the solution contains a significant amount of ethanol or isopropanol, it may be designated with the Irritant pictogram (⚠️) due to its potential to cause mild skin or eye irritation.

NFPA Ratings:

  • Health: 1 (Slight hazard)
  • Fire: 1 (Minor flammability, primarily in alcohol-based forms)
  • Reactivity: 0 (Stable under normal conditions)

Primary Risks

While low overall, the following exposures should be considered:

  • Inhalation: Minimal risk under normal use. Vapor from alcohol-based solutions may cause mild respiratory irritation with prolonged exposure or aerosolization.
  • Skin Contact: Usually well-tolerated; however, concentrated solutions may lead to dryness or irritation.
  • Eye Exposure: Can cause temporary stinging or irritation, especially if splashed.
  • Ingestion: Small amounts are generally safe, but concentrated alcohol-based products may cause stomach upset or mild intoxication.

With these baseline hazards in mind, we can now explore how witch hazel affects health in more detail. In the next section, we’ll take a closer look at exposure risks and potential health effects.

Exposure Risks & Health Effects

Witch hazel is widely considered safe for external use, especially when applied in moderate amounts and at typical concentrations. However, concentrated or alcohol-based formulations may introduce minor health risks, particularly through extended exposure or accidental misuse.

The following outlines potential effects based on different routes of exposure.

Inhalation Risks

  • Low toxicity risk, especially in water-based formulations.
  • Vapors from alcohol-based witch hazel may cause:
  • Lightheadedness
  • Mild respiratory irritation
  • Dizziness if inhaled in high volumes or poorly ventilated areas

Skin Contact Risks

  • Generally well-tolerated by most users.
  • Prolonged or repeated exposure to high-concentration solutions may cause:
  • Dryness
  • Mild irritation
  • Increased sensitivity in those with compromised or sensitive skin

Eye Contact Risks

  • May cause temporary irritation, burning, or stinging if splashed into the eyes.
  • Alcohol-based solutions are more likely to cause discomfort than water-based alternatives.

Ingestion Risks

Is witch hazel harmful if swallowed? In small quantities, witch hazel is not considered toxic and is sometimes found in herbal products. However, ingestion of concentrated or alcohol-based versions may lead to:

  • Nausea or vomiting
  • Mild intoxication (due to ethanol or isopropanol)
  • Gastrointestinal irritation

Although the risks are low for most everyday users, understanding how witch hazel interacts with the body helps ensure safer handling and informed use. If exposure does occur, it’s critical to know what to do next. In the following section, we’ll cover first aid measures for each type of exposure.

First Aid Measures

Though witch hazel is generally mild, knowing the appropriate first aid steps can help prevent discomfort or complications in the event of accidental exposure—especially with concentrated or alcohol-based solutions. The recommended responses vary slightly depending on the type of exposure.

Below is a breakdown of basic first aid procedures based on each route of exposure:

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By preparing for common exposure scenarios, users can respond effectively and safely. Up next, we’ll review handling and storage precautions to help reduce the risk of exposure altogether.

Handling & Storage Precautions

Proper handling and storage of witch hazel, especially in bulk or concentrated alcohol-based forms, is essential for maintaining a safe environment in laboratories, workplaces, and even home storage areas. While witch hazel is generally low-risk, it still requires attention to ventilation, sealing, and separation from incompatible substances.

Safe Handling Procedures

  • Work in well-ventilated areas, especially when using alcohol-based witch hazel to avoid inhaling vapors.
  • Avoid creating mists or aerosols through spraying or splashing.
  • If handling large volumes, wear:
  • Protective gloves to prevent skin dryness or irritation
  • Safety goggles to protect from accidental splashes

Storage Conditions

  • Store in a cool, dry area, away from direct sunlight and heat sources.
  • Keep containers tightly sealed when not in use to prevent evaporation or contamination.
  • Water-based solutions pose little flammability risk, but alcohol-based extracts should be treated with greater care.

Incompatible Substances

  • Store alcohol-based witch hazel solutions away from:
  • Open flames or ignition sources
  • Strong oxidizers
  • Strong acids or bases, which could react with alcohol components

By following these precautions, the risk of exposure, evaporation, or accidental reactions is significantly reduced. Next, we’ll review the correct procedures to follow in case of a spill or leak involving witch hazel.

Spill & Leak Procedures

While spills involving witch hazel are typically low-risk, proper cleanup procedures are essential, especially when dealing with alcohol-based solutions, which may pose a flammability or inhalation hazard. Prompt and careful containment can prevent slips, vapor buildup, and environmental release.

Here’s how to safely manage a spill or leak involving witch hazel:

Emergency Response Steps

  • Ventilate the area immediately, particularly in enclosed spaces or when a large spill involves an alcohol-based formulation.
  • Eliminate ignition sources (open flames, sparks, or hot surfaces) if alcohol is present.
  • Evacuate unnecessary personnel from the affected zone if significant vapors are detected.

Containment Methods

  • Use absorbent materials such as pads, paper towels, or inert absorbents (e.g., vermiculite or diatomaceous earth).
  • Avoid creating aerosols or splashing during cleanup.
  • Collect absorbed material into sealed, labeled containers for proper disposal.

Proper Disposal

  • Small quantities of witch hazel may often be disposed of with general non-hazardous waste, depending on local regulations.
  • For larger spills, especially involving ethanol or isopropanol, follow local hazardous waste disposal requirements or consult your environmental health and safety (EHS) department.

Once a spill is contained and cleaned, perform a final surface rinse with water and monitor for residual fumes or slipperiness. Coming up next, we’ll examine the fire and explosion hazards associated with witch hazel in formulations containing alcohol.

Fire & Explosion Hazards

Witch hazel’s fire risk is directly linked to its formulation. While water-based extracts are non-flammable and pose no combustion threat, alcohol-based witch hazel solutions, particularly those containing ethanol or isopropanol, can ignite under certain conditions and must be handled accordingly.

Flammability

  • Water-based witch hazel: Non-flammable
  • Alcohol-based witch hazel:
  • Classified as flammable under DOT and GHS guidelines
  • Vapors can ignite in the presence of open flames or high heat

Extinguishing Media

For alcohol-based solutions, use one of the following:

  • Foam
  • Dry chemical powder
  • Carbon dioxide (CO₂)

Avoid using water directly on large flammable liquid fires, as it may spread the material rather than extinguish it.

Firefighting Precautions

  • Wear protective gear, including breathing apparatus, when fighting fires involving witch hazel vapors.
  • Be aware that burning alcohol-based solutions may produce irritating fumes, including aldehydes and carbon oxides.
  • Cool containers exposed to heat with water spray to prevent pressure buildup or rupture.

Understanding these distinctions ensures fire safety planning is appropriate for the type of witch hazel in use. Next, we’ll explore how regulatory frameworks classify and govern witch hazel, including labeling and transportation requirements.

Regulatory & Compliance Information

While witch hazel is generally recognized as a safe, low-risk substance, regulatory oversight still applies (particularly for alcohol-based formulations), bulk handling, and products intended for pharmaceutical use. Knowing how witch hazel is classified under various agencies helps ensure full compliance with safety, transportation, and labeling standards.

OSHA Regulations

  • Witch hazel is not classified as hazardous under most OSHA standards.
  • However, workplace containers should be labeled according to the Hazard Communication Standard (HCS) if the product includes flammable alcohols or carries any risk of irritation.

EPA & Environmental Impact

  • Witch hazel is biodegradable and considered low risk to the environment.
  • No special EPA restrictions apply under normal consumer or laboratory use.
  • Alcohol-based versions should be disposed of properly to prevent environmental contamination.

DOT Transportation Regulations

  • Water-based witch hazel: Not regulated by the U.S. Department of Transportation (DOT).
  • Alcohol-based witch hazel (bulk quantities): May be regulated as a flammable liquid under DOT guidelines. Proper labeling and packaging are required for shipment.

FDA / USP / ACS Compliance

  • Witch hazel used in personal care or pharmaceutical applications must meet USP (United States Pharmacopeia) standards for purity and composition.
  • The FDA classifies witch hazel as an over-the-counter (OTC) active ingredient in certain skin care products.
  • For lab or reagent use, the chemical may be subject to ACS (American Chemical Society) purity specifications depending on the context.

With a clear understanding of compliance and classification requirements, users and businesses can handle witch hazel responsibly across industries. In the final section, we’ll highlight key technical documents available to support safe and informed use.

Technical Documents & References

For organizations, laboratories, and manufacturers working with witch hazel in regulated settings, access to up-to-date documentation is essential. These technical resources provide detailed information about safety, composition, and compliance, ensuring responsible use across all environments. Some key documents include: 

Safety Data Sheet (SDS)

Provides in-depth information on chemical hazards, safe handling procedures, emergency measures, and regulatory classifications. Required for workplace compliance and chemical inventory systems.

Certificate of Analysis (COA)

Includes batch-specific data on purity, formulation composition, and testing results. Crucial for quality assurance, especially in pharmaceutical and personal care manufacturing.

Technical Reports

Offer supporting research, stability data, and clinical insights on witch hazel’s safety, efficacy, and formulation performance in different use cases.

Accessing these documents supports safe practices and helps maintain product integrity across regulated applications. They’re especially important when handling bulk quantities or creating new formulations.

Whether you’re using witch hazel in a lab, manufacturing environment, or consumer product, safety starts with knowledge. By following best practices and referencing key technical documentation, users can minimize risk while maximizing the benefits of this natural compound.

Looking for high-quality, USP-grade witch hazel for your lab, product line, or research facility? Visit our store to explore our trusted selection and request a quote.

Conclusion

Whether you’re using witch hazel in a lab, manufacturing environment, or consumer product, safety starts with knowledge. By following best practices and referencing key technical documentation, users can minimize risk while maximizing the benefits of this natural compound.

Looking for high-quality, USP-grade witch hazel for your lab, product line, or research facility? Visit our store to explore our trusted selection and request a quote.


For more detailed guidance, explore our Resource Library for more information.

Our Customer Care team is also available for more information and documentation, including chemical Safety Data Sheets.
  


Where to Buy Witch Hazel

As your trusted partner in chemical supply, Lab Alley is always striving to meet the growing demands of our customers. We want you to be able to access all of your chemical needs in one place, along with streamlined online ordering and fast shipping.

Due to popular demand from our valued clientele, Lab Alley's Witch Hazel is available in a range of purities and packaging options to suit various commercial, laboratory, and personal needs.

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