Buy Antiviral Ingredients In Bulk To Make Your Own COVID-19 Hand Sanitizers, Disinfectant Wipes & Sprays | Isopropyl Alcohol, Ethanol, Hydrogen Peroxide, Glycerin & Benzalkonium Chloride For Sale Online | Create Your Own Purell Substitute

Buy The Correct Ingredients To Use For Properly Compounding Effective Alcohol-Based Hand Sanitizer Products During The COVID-19 Pandemic And Public Health Emergency

 

         

Safe Recipes For DIY Homemade Hand Sanitizers

 

What Ingredients Do You Need To Make Your Own Hand Sanitizer

Making your own hand sanitizer is easy to do and only requires a few ingredients:

The key to making an effective, germ-busting hand sanitizer is to stick to a 2:1 proportion of alcohol to aloe vera. This keeps the alcohol content around 60 percent. This is the minimum amount needed to kill most germs, according to the CDC. You can easily make it scented by adding in a few drops of essential oil or other fragrance. 

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COVID-19 has prompted healthcare firms to buy 1 gallon bottles5 gallon pails and 55 gallon drums of 70%91% and 99% isopropyl alcohol solutions at LabAlley.com. Lab Alley has been helping healthcare firms as they face historic challenges during the COVID-19 pandemic by shipping isopropyl alcohol (IPA) to their facilities.

Buy Aloe Vera Gel For $19.95 To Make DIY Hand Sanitizers

Aloe vera gel has soothing properties that make it great for irritated skin. It is one of the best natural moisturizers, containing vitamins, minerals, and antioxidants. Mix 3 parts isopropyl alcohol to 1 part aloe vera gel. Add a few drops of tea tree oil to give your hand sanitizer a pleasant scent. Two substances from Aloe vera – a clear gel and its yellow latex – are used to manufacture commercial products. Aloe gel typically is used to make topical medications for skin conditions, such as burns, wounds, frostbite, rashes, psoriasis, cold sores, or dry skin.

 

 

Buy Organic Tea Tree Oil For $9.95 To Make Homemade Hand Sanitizers

Tea tree oil has been proven time and time again to kill viruses, bacteria, mold, and fungi. It's also a natural anti-inflammatory. When you make your own hand sanitizer, as an extra protective measure and satisfying scent, you may want to consider adding a few drops of essential oil into the mixture. Add between 12 to 15 drops of an essential oil with antibacterial properties, like tea tree oil. Tea tree oil, also known as melaleuca oil, is an essential oil with a fresh camphoraceous odor and a colour that ranges from pale yellow to nearly colourless and clear. It is derived from the leaves of the tea tree.

 

 

Buy Lavender Essential Oil For $8.99 To Make DIY Hand Sanitizers

When it comes to natural hand sanitizer, ingredients are important. Lavender, tea tree and frankincense essential oils have great natural antiseptic properties. Lavender oil is an essential oil obtained by distillation from the flower spikes of certain species of lavender. Lavender use has been documented for over 2500 years. Romans used lavender oils for cooking, bathing and scenting the air. Lavender oils are also used for internal medical conditions, indigestion and heartburn. Lavender oil is said to soothe headaches, migraines and motion sickness when applied to the temples. It is frequently used as an aid to sleep and relaxation. Lavender oil is antibacterial and may even prevent scarring likely from its anti-inflammatory effects.

 

 

Buy Lemon Essential Oil For $6.99 To Make Your Own Hand Sanitizers 

Lemon or sweet orange oils are obtained as byproducts of the citrus industry. Before the discovery of distillation, all essential oils were extracted by pressing. Unlike other essential oils, lemon oil is usually cold pressed. Lemon essential oil can be added to a proper mixture of aloe vera gel and isopropyl alcohol as a component of an effective DIY hand sanitizer. In addition to lemon oil, other essential oils such as lavender, eucalyptus, and tea tree oil may be used as well to help mask the harsh scent of alcohol. Lemon essential oil is one of the most easily recognized oils because of its refreshing, energizing and uplifting scent. The health benefits of lemon oil can be attributed to its stimulating, calming, astringent, detoxifying, antiseptic, disinfectant and anti-fungal properties.

 

 

Buy Frankincense Essential Oil For $7.99 To Add To Homemade Hand Sanitizers

It is so easy to make your own hand sanitizer with frankincense essential oil.  By merely adding the frankincense essential oil to a simple base of rubbing alcohol and aloe vera gel, you can get the added benefits of essential oils to support the many systems in your body. The essential oil of frankincense is produced by steam distillation of the tree resin.

 

 

Buy Eucalyptus Essential Oil For $6.99 To Add To Your Homemade Hand Sanitizers And Sanitizing Solutions

The natural antibacterial properties of eucalyptus oil make it a good choice for DIY hand sanitizers. Eucalyptus oil is the generic name for distilled oil from the leaf of Eucalyptus, a genus of the plant family Myrtaceae native to Australia and cultivated worldwide. Eucalyptus oil has a history of wide application, as a pharmaceutical, antiseptic, repellent, flavouring, fragrance and industrial uses. The leaves of selected Eucalyptus species are steam distilled to extract eucalyptus oil. Eucalyptus oil is also used as a fragrance component to impart a fresh and clean aroma in soaps, detergents, lotions, and perfumes. It is known for its pungent, intoxicating scent. Sanitizing products made with eucalyptus oil fight foreign pathogens, bacteria, viruses and fungi.

 

 

How To Make Your Own Hand Sanitizer And Disinfectant Wipes 
Concerns over coronavirus have people stocking up on hand sanitizer and disinfectant wipes, but you might have all the ingredients you need at home!

Author: Chris Venzon (WFMY News2), Published: March 9, 2020

GREENSBORO, N.C. — Can't get your hands on any hand sanitizer or cleaning wipes? You might have all the ingredients you need to make your own at home.

The World Health Organization says hand-washing with soap and water is the best way to clean your hands, but when that's not an option, the agency recommends using an alcohol-based hand sanitizer and wipes with at least 70% alcohol; however, 99% isopropyl alcohol is the highest recommendation.

The ingredients for this modified recipe are commonly found at most major retailers and drug stores. If you can't find them anywhere, think outside the box - office supply stores and home improvement stores may also have supplies.

DIY Hand Sanitizer:

  • 2/3 cup rubbing alcohol of at least 70% alcohol concentration.
  • 1/3 cup Aloe Vera
  • *When using rubbing alcohol with higher alcohol concentrations, add water to the mix.
  • Mix well and fill dispenser of choice

DIY Disinfectant Wipes:

  • 2 cups of warm water
  • 1 cup rubbing alcohol of at least 70% alcohol concentration.
  • 1 tablespoon of dish soap
  • Mix well
  • Add mixture to half a roll of paper towels in a Tupperware container

Again, the World Health Organization says hand-washing with soap and water is the best way to clean your hands.

How Do You Make Hand Sanitizer With Essential Oils?

Ingredients:

 

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Ethyl Alcohol (70%) is the most effective concentration for bactericidal and virucidal uses70% ethyl alcohol sold by LabAlley.com is a potent cleaning agent used to kill viruses, destroy microbes, denature proteins and dissolves lipid (fat) membranes surrounding viruses. Alcohol denatures proteins by disrupting the side chain intramolecular hydrogen bonding. Read the CDC disinfection and sterilization guidelines for chemical disinfectants here. U.S. consumers can also buy 100% ethanol without a license at LabAlley.com.

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This website provides key EPA resources on the coronavirus disease (COVID-19). 70% antibacterial and antifungal denatured alcohol and ethanol sold online at LabAlley.com are great virucidal disinfectants and hand sanitizers against non-enveloped viruses as well as single-stranded, positive-sense RNA viruses such as coronaviruses (CoVs). Coronavirus is enveloped which means that it has a coating on the outside

Ethanol and isopropyl alcohol are used throughout the world for disinfecting environmental surfaces in health care communities and for hand disinfection and hand rubbing. It has been noted that ethanol has a stronger and broader virucidal activity than propanols such as isopropanol.

Coronaviruses are host-specific and can infect humans as well as animals, cats and dogs causing a variety of clinical syndromes. Dogs can contract coronaviruses, most commonly the canine respiratory coronavirus. This specific novel coronavirus (COVID-19) is not a health threat to dogs, but dogs can test positive for the virus.

Coronaviruses are single-stranded, positive-sense RNA viruses with a genome of approximately 30 kb, the largest genome among RNA viruses. These viruses were named coronaviruses because by electron microscopy they have club-shaped surface projections that give them a crownlike appearance. Coronaviruses derive their name from the fact that under electron microscopic examination, each virion is surrounded by a “corona,” or halo.

Non-enveloped viruses do not have a lipid-bilayer membrane. Non-enveloped viruses reproduce by breaching the membrane of a target host cell to get access to cytoplasm of the cell. A virus encased within a lipid bilayer is called an enveloped virus and a virus that does not have a bilayer is classified as a non-enveloped virus.

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Due to the coronavirus outbreak, U.S. businesses and consumers order EPA recommended disinfectants and sanitizers in bulk at LabAlley.com for cleaning and disinfecting for the coronavirus (SARS-CoV-2) and to kill germs on surfaces in households and community facilities.

The 70% ethyl alcohol sold by LabAlley.com is a better virucide than the 70% isopropyl alcohol and is quickly antimicrobial against viruses, bacteria and fungi on hard surfaces. 

Isopropanol (isopropyl alcohol ) and ethyl alcohol in aqueous solutions between 60% and 90% alcohol with 10% to 40% purified water, kill bacteria and viruses by denaturing their proteins and dissolving their lipid membranes. When a bacterial cell is exposed to a solution of ethyl alcohol or isopropyl alcohol, the amphiphile alcohol molecules bond with the molecules of the bacteria's cell membrane, making it more soluble in water. This reaction causes the cell membrane to lose its structural integrity and then fall apart.

 

Canada's Interim Guide On The Production Of Ethanol For Use In Alcohol-Based Hand Sanitizers
May 8, 2020

On This Page 

This document provides information on the use of ethanol as an ingredient in alcohol-based hand sanitizers sold in Canada. Numerous Canadian entities and industries not currently regulated by Health Canada have expressed interest in providing additional and/or alternate sources of ethanol (also known as anhydrous alcohol, ethyl alcohol, or grain alcohol) for use in the production of hand sanitizers to support the national response to the supply shortage during the COVID-19 pandemic.

To help reduce the risk of infection or spreading infection to others, Health Canada recommends that individuals wash their hands often with soap and water, or use an alcohol-based hand sanitizer if soap and water are not available. Similarly, the World Health Organization (WHO) recommends that individuals regularly and thoroughly clean their hands with soap and water, or an alcohol-based hand rub, as part of proper hand hygiene.

On March 27, 2020, Health Canada released the Guide on Health Canada's Interim Expedited Licensing Approach for the Production and Distribution of Alcohol-Based Hand Sanitizers. The purpose of that Guide is to support companies that intend to manufacture, package, label and/or distribute alcohol-based hand sanitizers in response to the current shortage by providing a simplified and expedited pathway to obtaining the required authorizations.

This document provides further guidance on the quality requirements for ethanol to be used in the production of hand sanitizers. It also highlights key formulation aspects and points to additional flexibilities that can be leveraged during this emergency situation.

To protect the health and safety of Canadians, Health Canada remains committed to its mandate while balancing the need for exceptional measures during the COVID-19 pandemic. As such, the quality of ethanol used in manufacturing hand sanitizers must be fit for purpose and meet safety, efficacy and quality requirements.

This interim approach takes into account the current policies and best practices of foreign regulatory partners, including the United States (US) Food and Drug Administration (FDA), as well as the recommendations of the WHO and the US Pharmacopeia (USP).

Acceptable Quality Grades

Ethanol used for the production of hand sanitizers should conform to one of the identity and purity criteria published in any of the following quality standards, with any noted deviations provided in this interim guidance. For details on these quality standards, please refer to the weblinks provided below. Please note that some of these references may be accessed for free, while others require payment for full access:

The USP monograph specifies that ethanol must be 94.9% to 96.0% pure by volume, and provides the following concentration limits for impurities commonly found in ethanol:

  • Methanol: No more than 200 µL/L
  • Acetaldehyde and acetal: No more than 10 µL/L, expressed as acetaldehyde
  • Benzene: No more than 2 µL/L
  • Sum of all other impurities: No more than 300 µL/L

Recommended Formulation

All formulations must meet the safety and efficacy requirements established in Health Canada’s Antiseptic Skin Cleansers (Personal Domestic Use) monograph.

Health Canada recommends the manufacturing of ethanol‑based hand sanitizer as per the WHO formulation. Specifically, the WHO-recommended handrub formulations (2010) provides a recipe for the preparation of a hand sanitizer with a final concentration of 80% v/v ethanol. While Health Canada’s monograph stipulates a range of 60%-80 v/v ethanol, an 80% v/v concentration is recommended for increased efficacy.

Formulation For A 10-Litre Preparation 

Other Acceptable Formulations Include: 

Records

Records must be maintained on how the hand sanitizer is prepared, including details on how the final ethanol dilution in the finished product was derived. The amount of ethanol needed in the formulation should be calculated using the following equation (as set out in the USP guidance):

How To Calculate The Amount Of Ethanol In A Hand Sanitizer Formulation

Non-Medicinal Ingredients (NMIs)

All NMIs added to a hand sanitizer product must be listed in Health Canada’s Natural Health Products Ingredient Database (NHPID), indicated with an acceptable purpose and comply with all listed restrictions (as per the NHPID). Additional information is outlined below on quality requirements for specific NMIs used in ethanol-based hand sanitizers, based on the WHO guidance:

NMI  Quality Requirements
Hydrogen Peroxide The low concentration of Hydrogen peroxide in the finished product (0.125%) is intended to help eliminate contaminating spores in the bulk solutions and recipients and is not an active substance for hand antisepsis.
Glycerol and other humectants or emollients

Glycerol (also known as glycerine or 1,2,3-Propanetriol) is added as a humectant at a final concentration of 1.45%, to increase the acceptability of the product and not to enhance viscosity.

Other humectants or emollients at a similar concentration may be used for skin care, provided that they are affordable, available locally, miscible (mixable) in water and alcohol, non-toxic, and not likely to cause an allergic reaction. Glycerol has been chosen because it is safe and relatively inexpensive. Lowering the percentage of glycerol may be considered to further reduce the stickiness of the handrub.

Use of proper
water
While sterile distilled water is preferred, boiled and cooled tap water may also be used as long as it is free of visible particles.
Addition of other additives It is strongly recommended that no ingredients other than those specified in this document be added to the formulations. All NMIs  (including denaturants) must be listed in the Product Licence application. If additions or substitutions of an NMI are made after the product licence is issued, documentation must be maintained on the safety of the additive and its compatibility with the other ingredients. These documents must be available upon request by Health Canada. Any substitutions should come from approved ingredients in the NHPID. If the NMI that you intend to use is not found in NHPID, you can complete a Natural Health Products Ingredients Database Issue Form and submit to this email to add the ingredient. The full list of ingredients must be provided on the product label.
Denaturants The use of denaturants is recommended to avoid the unintentional ingestion of hand sanitizers (particularly by children), but is not required under this interim approach. The NHPID includes a listing of acceptable denaturants that should be used if applicable in your formulation. Once this interim approach ceases to be in effect, to continue with the manufacture of hand sanitizer products, companies will be required to confirm with Health Canada that denaturants will be used from that point on.
Gelling agents No data are available to assess the suitability of adding gelling agents to WHO-recommended liquid formulations; any additives selected for this purpose must be listed in Health Canada’s NHPID and comply with listed restrictions. The addition of a gelling agent must be included in the list of ingredients on the product label.
Fragrances Adding fragrances, while not prohibited, is not recommended because of the risk of potential allergic reactions. As with other ingredients, a fragrance would be considered an NMI and must be included in the Product Licence application and be listed on the product label.

 

Formula Substitutions

Ingredients adhering to USP (or other acceptable standards, as listed above) should be used as the source of ingredients. However, given that there may currently be shortages of ingredients used to manufacture formulations of alcohol-based hand sanitizers, the following substitutions are acceptable:

  • When components meeting compendial quality standards are not obtainable, components of similar quality – such as those that are chemically pure, analytical reagent grade, or American Chemical Society-certified – may be used.
  • No ingredients should be added to enhance viscosity as they may decrease the effectiveness of the final preparation.

Disinfectant product ingredients, whether registered with the US Environmental Protection Agency or Health Canada, are not suitable as components for manufacturing hand sanitizers as they may not be safe for use on skin (i.e., may cause burns).

Use Of Non-USP Grade Alcohol

As per the Natural Health Products Regulations (NHPR), a Product Licence will not be issued if a product is likely to result in injury to the health of the consumer. Non-USP grade ethanol should be of a level of quality that is fit for human use in the finished hand sanitizer formulation.

For any products containing ethanol with specifications that deviate from the recommended standards, such as higher than permitted level of impurities in the above referenced standards, a risk assessment must be conducted and submitted to Health Canada for review. Each risk assessment will be evaluated on a case-by-case basis to determine if the ethanol is safe for use in hand sanitizer production. In the risk assessment, particular attention should be given to identify and quantify impurities, which are expected to be present (or likely to be present) as a result of manufacturing processes, starting materials, etc. An example of some impurities that would be expected in a non-USP or food grade ethanol product include acetaldehyde, benzene and methanol, though there may be others as well. Documentation including certificates of analysis (CoA) must be kept on record and made available at the request of Health Canada.

Excise Tax Implications

The Canada Revenue Agency (CRA) administers the Excise Act, 2001 which governs the federal taxation of several commodities, including spirits, and regulates activities involving the manufacture, possession and distribution of these products. For example, persons who produce and package spirits, persons who use non-duty-paid spirits in the manufacture of non-beverage spirit-based products such as cosmetics or hand sanitizers, and persons who operate warehouses to store non-duty-paid alcohol must possess an excise duty licence issued under the Excise Act, 2001.

Depending on the circumstances, a person may require a spirits licence, a user’s licence and/or a specially denatured alcohol registration in order to legally produce hand sanitizer using non-duty-paid alcohol in Canada. There are a number of ways hand sanitizer can be produced by licensees or registrants without incurring an excise duty liability, for example:

  • A user licensee can produce hand sanitizer in accordance with an approved formulation without the payment of excise duty on the final product.
  • There are also provisions that would allow a specially denatured alcohol registrant to possess and use certain grades of specially denatured alcohol to produce hand sanitizer without the payment of duty.
  • A spirits licensee is authorized under the Excise Act, 2001 to denature spirits according to specified criteria, which are not subject to excise duty.
  • Although it could be cost prohibitive, there is also the option to use duty-paid alcohol to produce hand sanitizer. 

The requirements under the Act will vary depending on the circumstances of each case and the proposed activities to be undertaken.

Obtaining A Licence, Registration And/Or Approved Formulation Under The Excise Act, 2001

A number of spirits licensees, licenced users and brewer licensees (excise licensees) have expressed an interest in using non-duty-paid alcohol to make hand sanitizer. These are existing excise licensees who are seeking to temporarily expand their operations in response to the shortage in supply as a result of the COVID-19 pandemic. In some cases, excise licensees are requesting specially denatured alcohol registrations to allow them to possess and use specially denatured alcohol for this purpose. In other cases, spirits or brewer licensees are requesting users’ licences and approved formulations. The CRA is also receiving enquiries from non-licensees who would like to apply for a specially denatured alcohol registration or user’s licence and approved formulation for the purpose of producing hand sanitizer. In response to the current circumstances, the CRA has implemented a streamlined process to expedite the review and approval of these applications.

Applications for users’ licences and specially denatured alcohol registrations should be submitted to your regional excise duty office using Form L63 Licence and Registration Application Excise Act, 2001. Applications for formulation approval should be submitted using Form Y15D - Request for Formula Approval. Note that a sample is not currently required for excise licensees applying for an approved formulation for the production of hand sanitizer. For questions or further information, please visit this website Excise Duties, Excise Taxes, Fuel Charge and Air Travellers Security Charge, which also includes the contact information for your regional excise duty office. These regional offices are your best source for information on excise taxes.

End Of Interim Approach

This interim approach is in effect immediately, and will be in effect until March 31, 2021 or until a notice is issued by Health Canada to licence holders (whichever is earliest). When the approach expires, production must cease, although existing product stock can be exhausted.

Contact Health Canada

If you have questions in relation to this Guide or the licensing of alcohol-based hand sanitizers, please contact Health Canada's Natural and Non-prescription Health Products Directorate at hc.nnhpd-dpsnso.sc@canada.ca

Information On Hand Sanitizer Ingredients From Wikipedia

Hand sanitizer is a liquid, gel, or foam generally used to decrease infectious agents on the hands. In most settings, hand washing with soap and water is generally preferred. Hand sanitizer is less effective at killing certain kinds of germs, such as norovirus and Clostridium difficile and unlike soap and water, it cannot remove harmful chemicals. People may incorrectly wiped off hand sanitizer before it has dried, and some are less effective because their alcohol concentrations are too low.

In most healthcare settings alcohol-based hand sanitizers are preferable to hand washing with soap and water. Reasons include it being better tolerated and more effective. Hand washing with soap and water; however, should be carried out if contamination can be seen, or following the use of the toilet. The general use of non-alcohol-based hand sanitizers has no recommendations.

Alcohol-based versions typically contain some combination of isopropyl alcohol, ethanol (ethyl alcohol), or n-propanol, with versions containing 60% to 95% alcohol the most effective. Care should be taken as they are flammable. Alcohol-based hand sanitizer works against a wide variety of microorganisms but not spores. Compounds such as glycerol may be added to prevent drying of the skin. Some versions contain fragrances; however, these are discouraged due to the risk of allergic reactions. Non-alcohol based versions typically contain benzalkonium chloride or triclosan; but are less effective than alcohol-based ones. 

Alcohol has been used as an antiseptic at least as early as 1363 with evidence to support its use becoming available in the late 1800s. Alcohol-based hand sanitizer has been commonly used in Europe since at least the 1980s. The alcohol-based version is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. The wholesale cost in the developing world is about US$1.40–3.70 per liter bottle.

Uses 

General Public 

The Clean Hands campaign by the US Centers for Disease Control and Prevention (CDC) instructs the public in hand washing. Alcohol-based hand sanitizer is recommended only if soap and water are not available.

When using an alcohol-based hand sanitizer:

  • Apply product to the palm of one hand.
  • Rub hands together.
  • Rub the product over all surfaces of hands and fingers until hands are dry.
  • Do not go near flame or gas burner or any burning object during applying hand sanitizer.
  • The current evidence for the effectiveness of school hand hygiene interventions is of poor quality.

Alcohol-based hand sanitizers may not be effective if the hands are greasy or visibly soiled. In hospitals, the hands of healthcare workers are often contaminated with pathogens, but rarely soiled or greasy. In community settings, on the other hand, grease and soiling is common from activities such as handling food, playing sports, gardening, and being active outdoors. Similarly, contaminants like heavy metals and pesticides (generally found outdoors) cannot be removed by hand sanitizers. Hand sanitizers may also be swallowed by children, especially if brightly-coloured.

Some commercially-available hand sanitizers (and online recipes for homemade rubs) have alcohol concentrations that are too low. This makes them less effective at killing germs. Poorer people in developed countries and people in developing countries may find it harder to get a hand sanitizer with an effective alcohol concentration. Fraudulent labelling of alcohol concentrations has been a problem in Guyana.

Health Care 

Hand sanitizers were first introduced in 1966 in medical settings such as hospitals and healthcare facilities. The product was popularized in the early 1990s.

Alcohol-based hand sanitizer is more convenient compared to hand washing with soap and water in most situations in the healthcare setting. Among healthcare workers, it is generally more effective for hand antisepsis, and better tolerated than soap and water. Hand washing should still be carried out if contamination can be seen or following the use of the toilet.

Hand sanitizer that contains at least 60% alcohol or contains a "persistent antiseptic" should be used. Alcohol rubs kill many different kinds of bacteria, including antibiotic resistant bacteria and TB bacteria. They also kill many kinds of viruses, including the flu virus, the common cold virus, coronaviruses, and HIV.

90% alcohol rubs are more effective against viruses than most other forms of hand washing. Isopropyl alcohol will kill 99.99 % or more of all non-spore forming bacteria in less than 30 seconds, both in the laboratory and on human skin.

The alcohol in hand sanitizers may not have the 10–15 seconds exposure time required to denature proteins and lyse cells in too low quantities (0.3 ml) or concentrations (below 60%). In environments with high lipids or protein waste (such as food processing), the use of alcohol hand rubs alone may not be sufficient to ensure proper hand hygiene.

For health care settings like hospitals and clinics, optimum alcohol concentration to kill bacteria is 70% to 95%. Products with alcohol concentrations as low as 40% are available in American stores, according to researchers at East Tennessee State University.

Alcohol rub sanitizers kill most bacteria, and fungi, and stop some viruses. Alcohol rub sanitizers containing at least 70% alcohol (mainly ethyl alcohol) kill 99.9% of the bacteria on hands 30 seconds after application and 99.99% to 99.999% in one minute.

For health care, optimal disinfection requires attention to all exposed surfaces such as around the fingernails, between the fingers, on the back of the thumb, and around the wrist. Hand alcohol should be thoroughly rubbed into the hands and on the lower forearm for a duration of at least 30 seconds and then allowed to air dry.

Use of alcohol-based hand gels dries skin less, leaving more moisture in the epidermis, than hand washing with antiseptic/antimicrobial soap and water.

Drawbacks

There are certain situations during which hand washing with soap and water are preferred over hand sanitizer, these include: eliminating bacterial spores of Clostridioides difficile, parasites such as Cryptosporidium, and certain viruses like norovirus depending on the concentration of alcohol in the sanitizer (95% alcohol was seen to be most effective in eliminating most viruses). In addition, if hands are contaminated with fluids or other visible contaminates, hand washing is preferred as well as after using the toilet and if discomfort develops from the residue of alcohol sanitizer use. Furthermore, CDC states hand sanitizers are not effective in removing chemicals such as pesticides.

Safety 

Fire
Alcohol gel can catch fire, producing a translucent blue flame. This is due to the flammable alcohol in the gel. Some hand sanitizer gels may not produce this effect due to a high concentration of water or moisturizing agents. There have been some rare instances where alcohol has been implicated in starting fires in the operating room, including a case where alcohol used as an antiseptic pooled under the surgical drapes in an operating room and caused a fire when a cautery instrument was used. Alcohol gel was not implicated.

To minimize the risk of fire, alcohol rub users are instructed to rub their hands until dry, which indicates that the flammable alcohol has evaporated. Igniting alcohol hand rub while using it is rare, but the need for this is underlined by one case of a health care worker using hand rub, removing a polyester isolation gown, and then touching a metal door while her hands were still wet; static electricity produced an audible spark and ignited the hand gel. Fire departments suggest refills for the alcohol-based hand sanitizers can be stored with cleaning supplies away from heat sources or open flames.

Skin
Research shows that alcohol hand sanitizers do not pose any risk by eliminating beneficial microorganisms that are naturally present on the skin. The body quickly replenishes the beneficial microbes on the hands, often moving them in from just up the arms where there are fewer harmful microorganisms.

However, alcohol may strip the skin of the outer layer of oil, which may have negative effects on barrier function of the skin. A study also shows that disinfecting hands with an antimicrobial detergent results in a greater barrier disruption of skin compared to alcohol solutions, suggesting an increased loss of skin lipids.

Ingestion
In the United States, the U.S. Food and Drug Administration (FDA) controls antimicrobial handsoaps and sanitizers as over-the-counter drugs (OTC) because they are intended for topical anti-microbial use to prevent disease in humans.

The FDA requires strict labeling which informs consumers on proper use of this OTC drug and dangers to avoid, including warning adults not to ingest, not to use in the eyes, to keep out of the reach of children, and to allow use by children only under adult supervision. According to the American Association of Poison Control Centers, there were nearly 12,000 cases of hand sanitizer ingestion in 2006. If ingested, alcohol-based hand sanitizers can cause alcohol poisoning in small children. However, the U.S. Centers for Disease Control recommends using hand sanitizer with children to promote good hygiene, under supervision, and furthermore recommends parents pack hand sanitizer for their children when traveling, to avoid their contracting disease from dirty hands.

There have been reported incidents of people drinking the gel in prisons and hospitals, where alcohol consumption is not allowed, to become intoxicated leading to its withdrawal from some establishments.

Absorption

On April 30, 2015, the FDA announced that they were requesting more scientific data based on the safety of hand sanitizer. Emerging science suggests that for at least some health care antiseptic active ingredients, systemic exposure (full body exposure as shown by detection of antiseptic ingredients in the blood or urine) is higher than previously thought, and existing data raise potential concerns about the effects of repeated daily human exposure to some antiseptic active ingredients. This would include hand antiseptic products containing alcohol and triclosan.

Surgical Hand Disinfection

Hands must be disinfected before any surgical procedure by hand washing with mild soap and then hand-rubbing with a sanitizer. Surgical disinfection requires a larger dose of the hand-rub and a longer rubbing time than is ordinarily used. It is usually done in two applications according to specific hand-rubbing techniques, EN1499 (hygienic handwash), and EN 1500 (hygienic hand disinfection) to ensure that antiseptic is applied everywhere on the surface of the hand.

Alcohol-Free 

Some hand sanitizer products use agents other than alcohol to kill microorganisms, such as povidone-iodine, benzalkonium chloride or triclosan. The World Health Organization (WHO) and the CDC recommends "persistent" antiseptics for hand sanitizers. Persistent activity is defined as the prolonged or extended antimicrobial activity that prevents or inhibits the proliferation or survival of microorganisms after application of the product. This activity may be demonstrated by sampling a site several minutes or hours after application and demonstrating bacterial antimicrobial effectiveness when compared with a baseline level. This property also has been referred to as "residual activity." Both substantive and nonsubstantive active ingredients can show a persistent effect if they substantially lower the number of bacteria during the wash period.

Laboratory studies have shown lingering benzalkonium chloride may be associated with antibiotic resistance in MRSA. Tolerance to alcohol sanitizers may develop in fecal bacteria. Where alcohol sanitizers utilize 62%, or higher, alcohol by weight, only 0.1 to 0.13% of benzalkonium chloride by weight provides equivalent antimicrobial effectiveness.

Triclosan has been shown to accumulate in biosolids in the environment, one of the top seven organic contaminants in waste water according to the National Toxicology Program Triclosan leads to various problems with natural biological systems, and triclosan, when combined with chlorine e.g. from tap water, produces dioxins, a probable carcinogen in humans. However, 90–98% of triclosan in waste water biodegrades by both photolytic or natural biological processes or is removed due to sorption in waste water treatment plants. Numerous studies show that only very small traces are detectable in the effluent water that reaches rivers.

A series of studies show that photodegradation of triclosan produced 2,4-dichlorophenol and 2,8-dichlorodibenzo-p-dioxin (2,8-DCDD). The 2,4-dichlorophenol itself is known to be biodegradable as well as photodegradable. For DCDD, one of the non-toxic compounds of the dioxin family, a conversion rate of 1% has been reported and estimated half-lives suggest that it is photolabile as well. The formation-decay kinetics of DCDD are also reported by Sanchez-Prado et al. (2006) who claim "transformation of triclosan to toxic dioxins has never been shown and is highly unlikely."

Alcohol-free hand sanitizers may be effective immediately while on the skin, but the solutions themselves can become contaminated because alcohol is an in-solution preservative and without it, the alcohol-free solution itself is susceptible to contamination. However, even alcohol-containing hand sanitizers can become contaminated if the alcohol content is not properly controlled or the sanitizer is grossly contaminated with microorganisms during manufacture. In June 2009, alcohol-free Clarcon Antimicrobial Hand Sanitizer was pulled from the US market by the FDA, which found the product contained gross contamination of extremely high levels of various bacteria, including those which can "cause opportunistic infections of the skin and underlying tissues and could result in medical or surgical attention as well as permanent damage". Gross contamination of any hand sanitizer by bacteria during manufacture will result in the failure of the effectiveness of that sanitizer and possible infection of the treatment site with the contaminating organisms.

Types 

Alcohol-based hand rubs are extensively used in the hospital environment as an alternative to antiseptic soaps. Hand-rubs in the hospital environment have two applications: hygienic hand rubbing and surgical hand disinfection. Alcohol based hand rubs provide a better skin tolerance as compared to antiseptic soap. Hand rubs also prove to have more effective microbiological properties as compared to antiseptic soaps.

The same ingredients used in over-the-counter hand-rubs are also used in hospital hand-rubs: alcohols such ethanol and isopropanol, sometimes combined with quaternary ammonium cations (quats) such as benzalkonium chloride. Quats are added at levels up to 200 parts per million to increase antimicrobial effectiveness. Although allergy to alcohol-only rubs is rare, fragrances, preservatives and quats can cause contact allergies. These other ingredients do not evaporate like alcohol and accumulate leaving a "sticky" residue until they are removed with soap and water.

The most common brands of alcohol hand rubs include Aniosgel, Avant, Sterillium, Desderman and Allsept S. All hospital hand rubs must conform to certain regulations like EN 12054 for hygienic treatment and surgical disinfection by hand-rubbing. Products with a claim of "99.99% reduction" or 4-log reduction are ineffective in hospital environment, since the reduction must be more than "99.99%".

The hand sanitizer dosing systems for hospitals are designed to deliver a measured amount of the product for staff. They are dosing pumps screwed onto a bottle or are specially designed dispensers with refill bottles. Dispensers for surgical hand disinfection are usually equipped with elbow controlled mechanism or infrared sensors to avoid any contact with the pump.

Production 

In 2010 the World Health Organization produced a guide for manufacturing hand sanitizer, which received renewed interest because of shortages of hand sanitizer in the wake of the COVID-19 pandemic. Dozens of liquor and perfume manufactures switched their manufacturing facilities from their normal product to hand sanitizer. In order to keep up with the demand, local distilleries started using their alcohol to make hand sanitizer. Distilleries producing hand sanitizer originally existed in a legal grey area in the United States, until the Alcohol and Tobacco Tax and Trade Bureau declared that distilleries could produce their sanitizer without authorization.

There are cautions against making your own hand sanitizer. Some widely-circulated home recipes are ineffective or even poisonous.

Composition 

World Health OrganizationThe has published a guide to producing large quantities of hand sanitizer from chemicals available in developing countries, where commercial hand sanitizer may not be available:

FORMULATION 1  10-L prep. Active ingredient (v/v) FORMULATION 2 10-L prep. Active ingredient (v/v)
Distilled water added to 10000 mL 18.425% Distilled water added to 10000 mL 23.425%
Ethanol 96% 8333 mL 80% Isopropyl alcohol 99.8% 7515 mL 75%
Glycerol 98% 145 mL 1.45% Glycerol 98% 145 mL 1.45%
Hydrogen peroxide 3% 417 mL 0.125% Hydrogen peroxide 3% 417 mL 0.125%

 

The WHO formulation are less viscous than commercial sanitizer gel, so like alcohol, they are a greater fire hazard.

Consumer alcohol-based hand sanitizers, and health care "hand alcohol" or "alcohol hand antiseptic agents" exist in liquid, foam, and easy-flowing gel formulations. Products with 60% to 95% alcohol by volume are effective antiseptics. Lower or higher concentrations are less effective; most products contain between 60% and 80% alcohol.

In addition to alcohol (ethanol, isopropanol or n-Propanol), hand sanitizers also contain the following:

Hydrogen peroxide may be added to inactivate spores within bottle of hand sanitizer but does not play a role when the hand sanitizer is used.

 

Buy Ethyl Alcohol And Isopropyl Alcohol At LabAlley.com To Kill Coronaviruses And Be Sure To Also Use Soap And Water

Ethyl alcohol, isopropyl alcohol and soap all kill the coronavirus. Soap contains fat-like substances known as amphiphiles, which are structurally very similar to lipids in virus membranes. Soap loosens the bond between viruses and skin which helps decrease the spread of viruses. Soap also loosens the Velcro-like interactions that hold the proteins, lipids and RNA in the virus together. Alcohol-based disinfectant products sold at LabAlley.com that contain a high-percentage alcohol solution (normally 70% ethanol and 70% isopropyl alcohol) kill viruses in the same way. Additionally, the mechanical action of hand washing with soap loosens viruses and bacteria from the skin.

The CDC recommends using an alcohol-based hand rub (ABHR) with greater than 60% ethanol or 70% isopropyl alcohol in healthcare environments. Unless hands are visibly soiled, an ABHR is recommended over soap and water in clinical situations because of evidence of better compliance compared to soap and water. Hand rubs are normally less irritating to hands and are effective in the absence of a sink.  Hands should be washed with soap and water for at least 20 seconds when visibly soiled, before eating, and after using the restroom. Learn more about hand hygiene in healthcare facilities here.

 

Buy Ethanol To Make Your Own Hand Sanitizers, Surface Disinfectants And Household Cleaners To Use Against Coronavirus (SARS-CoV-2)

Properly made homemade hand sanitizer solutions can destroy the coronavirus. Ethanol Alcohol (ethyl alcohol) can be used at home to make your own hand sanitizer mixtures. Alcohol (ethanol) used for alcohol-based hand sanitizers is derived from distillation or fermentation processes typically used for consumable goods. Antiviral hand sanitizer ingredients are for sale online here. 60% ethanol or 70% isopropyl alcohol inactivates viruses. Help protect against coronavirus by cleaning and disinfecting frequently touched surfaces and objects in your home like tables, doorknobs, light switches, countertops, handles, desks, phones, keyboards, toilets, faucets, sinks, etc.

 

Coronavirus Outbreak - Use Ethanol (Ethyl Alcohol) To Make Household Surface Disinfectants And Commercial Cleaners To Control Coronavirus COVID-19 (SARS-CoV-2)

To increase the supply of hand sanitizers, the FDA issued guidance for manufacturers that would like to produce alcohol (ethanol or ethyl alcohol) for use in alcohol-based hand sanitizers for consumers and health care personnel. LabAlley.com has addressed shortages of alcohol-based hand sanitizers associated with the COVID-19 pandemic by stocking the ingredients used to compound alcohol-based hand sanitizers. Buy safe chemical ingredients to make DIY homemade hand sanitizers and commercial cleaning solutions, here. Buy coronavirus disinfectants and sprays for household use, here. Prices for antiviral disinfectants, sanitizers and wipes start at $5.

Drinking methanol, ethanol or bleach DOES NOT prevent or cure COVID-19 and can be extremely dangerous. Methanol, ethanol, and bleach are poisons.

The World Health Organization (WHO) has reported an outbreak of disease caused by a novel coronavirus (referred to as 2019 Novel Coronavirus (2019-nCoV)).  This is an evolving situation, and it is recommended that all concerned consult the WHO, the United States Centers for Disease Control and Prevention (U.S. CDC) and the United States Environmental Protection Agency (U.S. EPA) websites frequently for the most updated information regarding the outbreak. 

Buy Alcohol-Based Disinfectants At LabAlley.com To Compound Hand Sanitizers And To Keep Viruses From Replicating

Alcohol-based hand sanitizer compounders protect children by using denatured ethanol or isopropyl alcohol. The FDA provides guidance on the production of alcohol-based hand sanitizer to help boost supply and protect public health during the Coronavirus (COVID-19) crisis. Viruses intricately interact with and modulate cellular membranes at several stages of their replication, but much less is known about the role of viral lipids compared to proteins and nucleic acids.

All animal viruses have to cross membranes for cell entry and exit, which occurs by membrane fusion (in enveloped viruses), by transient local disruption of membrane integrity, or by cell lysis. The CDC and the FDA are helping to keep children safe by recommending that compounders use denatured alcohol and isopropyl alcohol to formulate and manufacture hand sanitizers and coronavirus disinfectants. 

Viruses are obligatory intracellular parasites that are simple in structure and composition, but engage in multiple and complex interactions with their host. Virus replication occurs exclusively inside the respective host cell. Accordingly, viruses have to cross the host cell boundary at least twice during their replication cycle, for entry and exit. Because these viral membranes are derived from the host, they may contain a complement of membrane-bound host cell proteins.

Because denatured alcohol (ethanol/ethyl alcohol) tastes awful and it smells bad, this hand sanitizer ingredient discourages young children from eating coronavirus disinfectants. Denaturants in alcohol make it unfit for human consumption.

Buy 70% Denatured Alcohol And 70% Isopropyl Alcohol To Combat Coronavirus

Both 70% denatured ethanol (140 proof) and 70% isopropyl alcohol are excellent disinfectants for surface-cleaning uses. 70% isopropyl alcohol is frequently used as an antiseptic in hospitals. Because of an increased demand for alcohol-based hand sanitizers during the COVID-19 pandemic, many U.S. healthcare facilities are augmenting their cleaning supplies by ordering ethyl alcohol (70%) and 70% isopropyl alcohol at LabAlley.com. In April of 2020, tons of 70% alcohol were ordered online at LabAlley.com for large-scale disinfection efforts against coronavirus and for household cleaningsanitation and sterilization purposes in the U.S.

Buy antimicrobial disinfectants such as ethanol 70%, sodium hypochlorite and isopropanol to control Methicillin-resistant Staphylococcus aureus (MRSA) infections in homes and healthcare settings. Buy ingredients for safe recipes for DIY homemade hand sanitizers hereBuy coronavirus disinfectants here. Buy hospital grade disinfectants online here

     

    Safe Chemical Ingredients For Hand Sanitizers, Disinfectant Sprays And Antimicrobial Wipes For Sale At LabAlley.com

    Buy Antiviral Ingredients To Make Hand Sanitizers, Disinfectant Wipes And Sprays At LabAlley.com

    • Buy Natural Food Grade Additives
    • EPA-Registered Disinfectants
    • Pharmacy Grade Ingredients
    • Antiviral Chemical Compounds
    • Organic Raw Materials For The Safest Recipes For Hand Sanitizers
    • Hand Sanitizer Recipes And Antiseptic Topical Solution Recipes Are Listed Below
    • Hand Sanitizer Ingredient Prices And Disinfectant Ingredient Prices Are Listed Below

    DIY Hand Sanitizer (Antiseptic Topical Solution) Recipe # 1

    Homemade Hand Sanitizer (Antiseptic Topical Solution) Recipe # 2

      The Coronavirus has led some to make their own hand sanitizer. To make hand sanitizer, you'll need just two ingredients: aloe vera gel and isopropyl alcohol. You can create your own Purell substitute at home. The active ingredient many hand sanitizer recipe is the alcohol, which needs to comprise at least 60% of the product in order to be an effective disinfectant. Find out how to kill viruses here. Buy safe chemical ingredients to make DIY homemade hand sanitizers, sprays, wipes and disinfectants.

      To mix your own DIY homemade hand sanitizer because of the hand sanitizer shortage, use the popular germ-busting 'Make your own hand sanitizer' recipes explained here. You can fight COVID-19, by using a homemade hand sanitizer recipe that calls for 1 cup of 91% isopropyl alcohol and ½ cup of aloe vera gel in the recipe.

      You can mix (2:1 proportion) 91% or 99% isopropyl alcohol and a stabilizer like natural aloe vera gel to make an effective antiviral handrub to protect your hands. You can buy ingredients like ethanol (commonly available at 90%-95%) at LabAlley.com because they are hard to find at stores like Walgreens or Target. Get a good recipe for hand sanitizer using hydrogen peroxide here.

      The WHO's official instructions for a recipe for hand sanitizer using glycerin calls for denatured alcohol or isopropyl alcohol, glycerol (also known as glycerin), hydrogen peroxide and sterile water. Typical ingredients for sale at LabAlley.com that are listed in safe recipes for hand sanitizers and antiseptic topical solutions include ethanol (alcohol), isopropyl alcohol (IPA), hydrogen peroxide (H2O2), glycerol and high purity water.

      Safe recipes for DIY homemade hand sanitizers and handrubs include the following raw materials and various ingredients in their formulation and compounding instructions.

       

      Shop Online For The Best Rated Coronavirus Disinfectants And Virus Killers To Prevent The Spread Of Infectious Diseases At LabAlley.com
      05/01/20

      List N: Products With Emerging Viral Pathogens And Human Coronavirus Claims For Use Against SARS-CoV-2

        Isopropyl Alcohol For Coronavirus 

        If your local store is out of hand sanitizer, buy isopropyl alcohol (better known as rubbing alcohol) at LabAlley.com to make do-it-yourself sanitizers. Tests have confirmed that two hand sanitizer formulations recommended by the World Health Organization (WHO) inactivate the virus that causes coronavirus disease 19 (COVID-19). Hand sanitizer can be made out of either ethyl alcohol, like the ethanol in alcoholic beverages, or isopropyl alcohol. Rubbing alcohol that's at least 70% alcohol will also kill coronavirus on surfaces; 60% for your hands. 

        ExxonMobil makes isopropyl alcohol to help with the coronavirus effort. The firm recently reconfigured a facility to manufacture medical-grade hand sanitizer, which will be donated to health care providers and first responders. 

        How To Make Your Own Hand Sanitizer | Dr. Ian Smith

         

         

        U.S. Tariffs On Imports Of Sanitizer Ingredients And Raw Materials

        U.S. medical supply firms and online retailers of antiviral hospital grade sanitizers and coronavirus disinfectants such as LabAlley.com, have been challenged by U.S. tariffs on imports of hand sanitizers and chemical disinfectants such as glutaraldehyde, used to fight the COVID-19 pandemic.

         

        Raw Materials For DIY Homemade Hand Sanitizers For Sale Online At LabAlley.com

        Antiviral disinfection products, ingredients for topical solutions and hand sanitizers and antiviral chemical compounds are for sale at LabAlley.com.

         

        Alcohol-Based Hand Sanitizer Compounders Protect Children By Using Denatured Ethanol Or Isopropyl Alcohol

        The FDA provides guidance on the production of alcohol-based hand sanitizer to help boost supply and protect public health during the Coronavirus (COVID-19) crisis. The CDC and the FDA are helping to keep children safe by recommending that compounders use denatured alcohol and isopropyl alcohol to formulate and manufacture hand sanitizers and coronavirus disinfectants. Because denatured alcohol (ethanol/ethyl alcohol) tastes awful and it smells bad, this hand sanitizer ingredient discourages young children from eating coronavirus disinfectants. Denaturants in alcohol make it unfit for human consumption.

        To protect young children from accidental poisoning caused by unintentionally ingesting coronavirus disinfectants and hand sanitizers, the CDC and FDA are recommending that compounders and consumers use denatured alcohol, isopropyl alcohol, hydrogen peroxide, glycerin (glycerol) and sterile water to prepare alcohol-based hand sanitizers for consumer use and for use as health care personnel hand rubs. Get updated core disinfection/cleaning guidance from the CDC here.

        The USP Compounding Expert Committee (CMP EC) provides recommendations for compounding alcohol-based hand sanitizers for use during shortages associated with the COVID-19 pandemic. Download the USP recommendations here (PDF).

        Coronavirus disinfectants ordered online at LabAlley.com are used to clean the things that people touch the most such as phones, shopping carts, remote controls, tables, toilets, toothbrush holders, faucets, doorknobs, computer keyboards, light switches, desks, sinks and door handles.

        Consumers and alcohol-based hand sanitizer manufacturers can order approved denatured alcohol (isopropyl alcohol and denatured ethyl alcohol), hydrogen peroxide, USP and FCC grade glycerin (glycerol)antiviral disinfectants, hospital grade disinfectants, raw materials for hand sanitizer ingredients and sterile water online at LabAlley.com to make products to fight COVID-19.

        Distilleries, compounders, sanitizer manufacturers, botanical makers and American households purchase disinfectants and other cleaning supplies online at LabAlley.com to kill common viruses, mold, mildew, fungi, bacteria, pathogens and the novel coronavirus on contaminated surfaces.  Online orders of ingredients used to make coronavirus disinfectants, aerosol disinfectants and multipurpose cleaners surged in March of 2020.

        To learn more about U.S. regulations concerning the use of denatured alcohol, please refer to the Electronic Code of Federal Regulations here. For guidance from the FDA for using denatured alcohol to make commercial hand sanitizers, please refer to this PDF titled, "Policy for Temporary Compounding of Certain Alcohol-Based Hand Sanitizer Products During the Public Health Emergency Immediately in Effect Guidance for Industry".

         

        Does Hydrogen Peroxide Kill Coronavirus?

        Yes, in all probability, SARS-CoV-2 can be efficiently inactivated with surface disinfection procedures that use hydrogen peroxide ordered at LabAlley.com. That being said, no hydrogen product exists in the U.S. market that has been tested to kill SARS-CoV-2 and approved by U.S. regulatory agencies such as the EPA or FDA.

        Vaporized hydrogen peroxide is an effective decontamination method for masks and N95 respirators that have been contaminated by SARS-CoV-2. The U.S. Food and Drug Administration issued an emergency use authorization (EUA) to decontaminate compatible N95 or N95-equivalent respirators with vaporized hydrogen peroxide sterilizers.

        3% hydrogen peroxide purchased online at LabAlley.com is used as a spray sanitizer to kill rhinovirus on surfaces. Because scientists claim that coronaviruses are easier to kill than rhinovirus, hydrogen peroxide should kill SARS-CoV-2. Hydrogen peroxide should not be used to treat COVID-19, which is the disease caused by the novel coronavirus.

        Because the first confirmation of a case of 2019-nCoV (original name) was just confirmed on January 21, 2020, scientific studies and research to unequivocally validate that hydrogen peroxide will completely inactivate the SARS-CoV-2 virus are still ongoing. However, many products on the EPA List N Disinfectants For Use Against SARS-CoV-2 contain hydrogen peroxide. Duke University and Health System, will begin using hydrogen peroxide vapor to decontaminate and reuse N95 respirators.

        Hydrogen peroxide is active against a wide range of microorganisms, including bacteria, yeasts, fungi, viruses, and spores. The CDC provides information on the effectiveness of hydrogen peroxide solutions against viruses. The hydrogen peroxide solutions listed on the CDC website include 0.5% accelerated hydrogen peroxide, 3% concentration, 6% hydrogen peroxide, 10% hydrogen peroxide solution, 7% stabilized hydrogen peroxide and 13.4% hydrogen peroxide.

         

         

         

        Buy Medical Grade Antiviral Disinfectants Online | Order Hospital Grade Disinfectants Here | Purchase Coronavirus Disinfectants At LabAlley.com

         

        How To Make Antiviral Hand Sanitizers, Cleaning Products And Disinfectants

        Buy Ingredients Recipes For Hand Sanitizers In Bulk Online Here Or By Phone: 512-668-9918

        If you have questions about ordering ingredients in bulk for recipes for hand sanitizers online here at LabAlley.com or would like to place an order, call 512-668-9918 or email customerservice@laballey.com to talk with an Hand Sanitizer Specialist. Use this 10% discount code to buy hand sanitizer ingredients online or by phone in the U.S: LAB10OFF.  

        Get information from Google to help your small business manage through the uncertainty caused by COVID-19 here. Buy antiviral hospital grade disinfectants, hand sanitizers, sterilization sprays, cleaners and detergents here. Buy antiviral hand sanitizer ingredients, antiviral disinfectants, antiviral products And antiviral chemical compounds at wholesale prices here. Buy supplies and chemical ingredients to make coronavirus disinfection products hereViruses can be eliminated with soap, bleach, alcohol, food or UV light.

         

        U.S. medical supply firms and online retailers of antiviral hospital grade sanitizers and coronavirus disinfectants such as LabAlley.com, have been challenged by U.S. tariffs on imports of hand sanitizers and chemical disinfectants such as glutaraldehyde, used to fight the COVID-19 pandemic.

         

        Recipe For Hand Sanitizer Using Essential Oils | Ingredients 

        • 2 tablespoons rubbing alcohol at least 70%
        • 1 tablespoon aloe vera gel
        • 2 teaspoons vegetable glycerin
        • 4 drops Tea Tree Essential Oil
        • 3 drops Lemon Essential Oil
        • 3 drops Lavender Essential Oil
        • 2 oz flip-top container  

        How Do You Make Your Own Hand Sanitizer?

        Dr. Rishi Desai, chief medical officer of Osmosis, and a former epidemic intelligence service officer in the division of viral diseases at the CDC, says that the hand sanitizer recipe below will kill 99.9 percent of germs after 60 seconds.

        Hand Sanitizer Recipe | What You’ll Need:

        Directions: 

        • Pour all ingredients into a bowl, ideally one with a pouring spout like a glass measuring container.
        • Mix with a spoon and then beat with a whisk to turn the sanitizer into a gel.
        • Pour the ingredients into an empty bottle for easy use, and label it “hand sanitizer.”

        Jagdish Khubchandani, PhD, associate professor of health science at Ball State University, shared a similar formula.

        His hand sanitizer formula combines: 

        If you are making hand sanitizer at home, Khubchandani says to adhere to these tips:

        • Make the hand sanitizer in a clean space. Wipe down counter tops with a diluted bleach solution beforehand.
        • Wash your hands thoroughly before making the hand sanitizer.
        • To mix, use a clean spoon and whisk. Wash these items thoroughly before using them.
        • Make sure the alcohol used for the hand sanitizer is not diluted.
        • Mix all the ingredients thoroughly until they are well blended.
        • Do not touch the mixture with your hands until it is ready for use.

        For a larger batch of hand sanitizer, the World Health Organization (WHO) has a formula for a hand sanitizer that uses:

        Is It Safe?

        DIY hand sanitizer recipes are all over the internet these days — but are they safe?

        These recipes, including the ones above, are intended for use by professionals with both the expertise and resources to safely make homemade hand sanitizers. Homemade hand sanitizer is only recommended in extreme situations when you’re unable to wash your hands for the foreseeable future.

        Improper ingredients or proportions can lead to:

        • lack of efficacy, meaning that the sanitizer may not effectively eliminate risk of exposure to some or all microbes
        • skin irritation, injury, or burns
        • exposure to hazardous chemicals via inhalation 

        Homemade hand sanitizer is also not recommended for use with children. Children may be more prone to improper hand sanitizer usage, which could lead to greater risk for injury.

        What Germs Can Hand Sanitizer Kill? 

        According to the CDCTrusted Source, an alcohol-based hand sanitizer that meets the alcohol volume requirement can quickly reduce the number of microbes on your hands. It can also help destroy a wide range of disease-causing agents or pathogens on your hands, including the novel coronavirus SARS-CoV-2.

        However, even the best alcohol-based hand sanitizers have limitations and do not eliminate all types of germs.

        According to the CDC, hand sanitizers won’t get rid of potentially harmful chemicals. It’s also not effective at killing the following germs: 

        Also, a hand sanitizer may not work well if your hands are visibly dirty or greasy. This may happen after working with food, doing yard work, gardening, or playing a sport.

        If your hands look dirty or slimy, opt for handwashing instead of a hand sanitizer. 

         

        Buy Coronavirus Disinfectants For Professional Cleaning Staffs

        Cleaning professionals use coronavirus disinfection products ordered online at LabAlley.com to clean and safely disinfect for the novel coronavirus (SARS-CoV-2). The ISSA (Worldwide Cleaning Industry Association) offers education, training, and business resources to help cleaning workers manage the COVID-19 outbreak. Learn how to get trained to clean and disinfect for coronavirus here.

         

        Buy The Best Virus Disinfectants, Antimicrobial Sprays, Antibacterial Wipes And Household Cleaning Supplies Online

        Antimicrobial Products That Are Effective Against Norovirus (Norwalk-Like Virus)
        April 8, 2020

        For pesticide registration information, review this list from the EPA, "List G: EPA’s Registered Antimicrobial Products Effective Against Norovirus (Norwalk-Like Virus)". 

        Notes About This List

        • All EPA-registered pesticides must have an EPA registration number, which consists of a company number and a product number (e.g., 123-45). Alternative brand names have the same EPA registration number as the primary product.
        • When purchasing a product for use against a specific pathogen, check the EPA Reg. No. versus the products included on this list.
        • In addition to primary products, distributors may also sell products with formulations and efficacy identical to the primary products. Distributor products frequently use different brand names, but you can identify them by their three-part EPA registration number (e.g., 123-45-678, which represents a distributor product identical to the product example listed above, EPA Reg. No. 123-45).
        • If you would like to review the product label information for any of these products, please visit the EPA product label system.
        • Information about listed products is current as of the date on this list.
        • Inclusion on this list does not constitute an endorsement by EPA.

        View more information about EPA lists of registered antimicrobial products here. You may need a PDF reader to view some of the files on this page. See EPA’s About PDF page to learn more. 

        • Download List G: EPA’s Registered Antimicrobial Products Effective Against Norovirus (PDF)(6 pp, 130 K, March 4, 2020)
        • Contact the EPA about pesticide labels, to ask a question, provide feedback, or report a problem. 

        About The EPA Pesticide Product and Label System

        The Pesticide Product and Label System (PPLS) provides a collection of pesticide product labels (Adobe PDF format) that have been accepted by EPA under Section 3 of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). New labels were added to PPLS on April 08, 2020.

        • Search EPA Registration, Distributor Product, or Special Local Need Number Here
        • The EPA Registration Number (EPA Reg. No.) appears on all registered pesticides sold in the United States. It is usually found on the back panel of the label along with the detailed instructions for use.
        • Enter the company number (the first set of digits before the dash) to see all products marketed by that company or the entire number (including the dash) to view the label for a particular product.
        • To search by Special Local Need Number, please enter two-letter state abbreviations with or without 6 digit number (i.e. OH123456).
        • Search Buy Product or Alternative Brand Name: Enter the name of the product. As you type, options will be presented to you. Keep in mind that product names may vary, so if you don’t find the product you are looking for, try the EPA Registration Number Search.
        • Search By Company Name: Enter the name of the company. Some companies may have several divisions that manufacture and market pesticides products. You can select among these divisions using the drop-down list or choose the root of the company name (e.g., "Bayer" or "3M") to see products associated with all of the divisions.
        • Search By Company Number: Enter the company number. Please use digit without dash.
        • Search By Chemical Name (Active Ingredient): Enter the name of the chemical (Active Ingredients only) you are interested in. Because there are many naming conventions for chemicals, you can enter the common chemical name of the chemical or other variants, including scientific names or partial names. This search function will help guide you to products that contain that active ingredient.
        • Search By CAS Number Or PC Code: Enter the CAS Number or PC Code you are interested in. You may use the % wild card before and/or after your entry to enter a partial value.

        About Pesticide Labels

        Regulation Of Pesticide Labels

        Information On Pesticide Product Label Topics

        Get Help With Pesticide Label Issues

         

        Types of Disinfectants With Examples | Microbiology with Sumi 

        The "Microbiology With Suma" YouTube channel cover various topics related to several branches of microbiology including virology

         

         

        EPA Announced New Surface Disinfectant Products Added to List N in Effort to Combat COVID-19
        The National Law Review | Saturday, April 4, 2020

        On April 2, 2020, the U.S. Environmental Protection Agency (EPA) announced the addition of new surface disinfectants on EPA’s List N: Disinfectants for Use Against SARS-CoV-2 (List N) that may be used to combat SARS-CoV-2, the novel coronavirus that causes COVID-19. List N now contains 357 products. The webpage for List N also now has enhanced functionality to allow users to sort these products by surface type and use site. EPA states that it continues to expedite the review process for new disinfectants.

        Previously, all products on List N had to have either an EPA emerging viral pathogen claim or have demonstrated efficacy against another human coronavirus. EPA now has expanded List N to include products on EPA’s List G: EPA’s Registered Antimicrobial Products Effective against Norovirus and List L: Products Effective against the Ebola Virus, as these products also meet EPA’s criteria for use against SARS-CoV-2.

        EPA has updated List N to include the types of surfaces on which products can be used (e.g., hard or soft) and use sites (e.g., hospital, institutional or residential). Products applied via fogging or misting are now noted in the formulation column. This additional information allows the public to choose products that are appropriate for their specific circumstances.

        Additionally, EPA has updated the Frequently Asked Questions (FAQ) EPA has posted about disinfectants related to coronavirus. The FAQ update provides new information on pesticide safety, enforcement, and pesticide devices. It also includes enhanced explanations of why List N products are qualified for use against SARS-CoV-2 and how these products can be used most effectively.

        EPA states that it has continued to adapt its processes to ensure the supply of disinfectants keeps pace with demand. EPA recently announced additional flexibility that allows manufacturers of already-registered EPA disinfectants to obtain certain active and inert ingredients from any source of suppliers without prior approval by EPA. EPA also added 48 additional chemicals to its list of commodity inert ingredients. EPA states that this regulatory flexibility aims to help ease the production and availability of EPA-registered disinfectants.

        EPA also is expediting all requests for company numbers and establishment numbers to enable new pesticide-producing establishments to come online as quickly as possible. 

        Additional information on EPA’s efforts to address the novel coronavirus is available here.

        Guide to Local Production: WHO-recommended Handrub Formulations

        This Guide to Local Production of WHO-recommended Handrub Formulations is separated into two discrete but interrelated sections. Part A provides a practical guide for use at the pharmacy bench during the actual preparation of the formulation. Users may want to display the material on the wall of the production unit. Part B summarizes some essential background technical information and is taken from WHO Guidelines on Hand Hygiene in Health Care (2009). Within Part B the user has access to important safety and cost information and supplementary material relating to dispensers and distribution. Read more here.

        16 Safer Disinfectants To Use Against Coronavirus
        April 7, 2020

        Both the United States Environmental Protection Agency (EPA) and the American Chemistry Council have lists (here and here) of products that do one of two things. Each product either complies with the EPA’s emerging viral pathogen guidance, with demonstrated efficacy against viruses harder to kill than SARS-CoV-2 (the virus that causes COVID-19), or have demonstrated efficacy against another human coronavirus similar to SARS-CoV-2. Read more here.

        How To Make (And Use) A Disinfectant Against Coronavirus
        New York Times | April 7, 2020

        Here's a guide to working with sprays, wipes and a bleach-based solution to clean surfaces of the pathogen. 

        The coronavirus that causes Covid-19 may survive for several days on some surfaces. Estimates of its life span vary, but the virus can clearly hang around long enough to make disinfecting frequently touched surfaces a priority. Normally, disinfectants, like Lysol and Clorox wipes, are available and would do the trick in cleaning most surfaces of contagions, but many of these items have been widely out of stock across the United States. If you cannot find any of these products, you can make an effective homemade disinfectant from a mixture of water and bleach. Read more here.

        Protection For U.S. Consumers From Fraudulent Coronavirus Disinfectant Claims
        Posted on April 4, 2020 

        U.S. Environmental Protection Agency (EPA) Administrator Andrew Wheeler hosted an interactive telephone call with U.S. retailers and third-party marketplace platforms to discuss imposter disinfectant products and those that falsely claim to be effective against the novel coronavirus, SARS-CoV-2, the cause of COVID-19. The E.P.A. has threatened legal proceedings against vendors of bogus coronavirus (COVID-19) cleaners, disinfectants and sanitizers. While such products might not be harmful, they offer the public a dangerously false sense of protection that could deter social distancing and promote the spread of COVID-19. The federal government is asking online retailers to take unregistered products that falsely claim protection from coronavirus off the market. The EPA has continued to add new surface disinfectant products to List N in an effort to combat COVID-19. Any brand that claims to kill or repel bacteria or viruses should be tested and registered by the E.P.A. and with the federal government. 

        Buy Safe Ingredients And Chemicals For DIY Homemade Hand Sanitizers, Cosmetics, Makeup, Lotions, Soaps, Household Cleaning Products, Laboratory Sterilization, Food And Beverage Processing, Skin Care Formulations, Hospital Disinfectants, Personal Care Products, Botanical And Essential Oils, Botanical Extracts, Pharmaceutical Drugs, Herbal Tinctures, Kid Safe Pools, Pest Control Products, Lawn Care Products, Chemistry Labs, Natural Health Supplements And Vitamins, Coronavirus Disinfection Products, Perfumes, Hospital Grade Detergents, Disinfecting Wipes And Disinfectant Sprays At LabAlley.com

        Buy bulk natural ingredients and antiviral chemicals, bulk food grade chemicals and organic raw materials for safe recipes for DIY homemade hand sanitizers here. Buy antiviral hand sanitizer ingredients, antiviral disinfectants, antiviral products and antiviral chemical compounds here. Buy antiviral hospital grade disinfectants, pharmaceutical grade substances, hand sanitizers, sterilization sprays, wipes, cleaners and detergents here

        Buy lab supplies, laboratory glassware, chemical crystals and powders, oils, gels, spray bottles and stock chemical solutions to make Coronavirus disinfectants here. You can also buy other compounds and additives for safe hand sanitizer recipes, cosmetics and personal care products at LabAlley.com. Find out how chemicals are made, sold, priced, bought, shipped and used in the United States here.

        Popular additives for skin care products purchased online in bulk at wholesale prices at LabAlley.com include food grade ethanol, 100% alcohol, 95% alcohol, 70% alcohol, 99% isopropyl alcohol, 91% isopropyl alcohol, 70% isopropyl alcohol, 3% hydrogen peroxide, 6% hydrogen peroxidefood grade hydrogen peroxide, food grade (FCC) vegetable glycerin, Food Grade (FCC) glycerol, solvents, aqueous acids and acids in crystalline powder form.

        Shop for popular ingredients used to formulate DIY homemade personal care products such as high purity water, citric acid, menthol crystalsnatural peppermint oil, Polysorbate 80, phenol, trichloroacetic acid  (TCC), denatured alcoholn-Propanol, MCT (Coconut Oil), sodium hypochloritesalicylic acid, fumaric acidsodium hydroxide, triethanolaminebenzalkonium chloridetriethylene glycolpropylene glycol, ammonium hydroxide, olive oil at LabAlley.com. Buy antiviral hand sanitizer ingredients, antiviral disinfectants, antiviral products and antiviral chemical compounds here. Buy antiviral hospital grade disinfectants, pharmaceutical grade substances, hand sanitizers, sterilization sprays, wipes, cleaners and detergents here. Buy lab supplies, chemical powders, oils, gels, spray bottles and chemical solutions to make Coronavirus disinfectants here at LabAlley.com.

         

        Cleaning And Disinfection Of Sterile Processing Facilities | Hand Sanitizers 

        Hand sanitizers fall into two groups: alcohol-based, which are more common; and non-alcohol-based. The most commonly used alcohol-based hand sanitizers are isopropyl alcohol or a form of denatured ethanol (i.e. industrial methylated spirits), normally at a 70% concentration. Sanitizers are applied to either bare skin (on entering a cleanroom) or to gloved hands (within the cleanroom). Read more here.

         

        Hand Sanitizer Recipes Are Listed Below

        Compounding Alcohol-Based Hand Sanitizer During COVID-19 Pandemic
        March 24, 2020

        This document is for informational purposes only and is intended to address shortages of alcohol-based hand sanitizers associated with the COVID-19 pandemic. This does not reflect the Compounding Expert Committee’s opinions on future development or revisions to official text of the USP-NF. USP is actively monitoring the evolving situation and will update this document accordingly. 

        Background and Introduction 

        In light of the rapidly evolving COVID-19 pandemic, there is an expected shortage of alcohol-based hand sanitizers. The Centers for Disease Control (CDC) recommends washing hands with soap and water whenever possible because handwashing reduces the amounts of all types of germs and chemicals on hands. If soap and water are not available, using a hand sanitizer with a final
        concentration of at least 60% alcohol can help you avoid getting sick and spreading germs to others. Noting that consumers are experiencing difficulties in accessing alcohol-based hand sanitizers containing at least 60% alcohol, on March 14, 2020, FDA released an Immediately in Effect Guidance titled, “Policy for Temporary Compounding of Certain Alcohol-Based Hand Sanitizer
        Products During the Public Health Emergency.” During this pandemic, USP supports State Boards and other regulators using risk-based enforcement discretion related to the compounding of alcohol-based hand sanitizers for consumer use. 

        The USP Compounding Expert Committee (CMP EC) provides the following recommendations for compounding alcohol-based hand sanitizers for use during shortages associated with the COVID-19 pandemic. In light of the public health emergency posed by COVID-19, this document was developed without a public comment period. This document is not a USP compendial standard; rather, it reflects considerations developed by the USP CMP EC, based on their scientific and professional expertise, and with input from regulatory agencies at the federal and state level. If implementing the provisions in this document, the expectation is that compounders follow USP General Chapter <795>
        Pharmaceutical Compounding – Nonsterile Preparations, including the following:

        • Personnel trained in the compounding procedures
        • USP, NF or Food Chemicals Codex (FCC) grade ingredients as the recommended source of ingredients | When components meeting compendial quality standards are not obtainable, components of equivalent quality – such as those that are chemically pure, analytical reagent grade or American Chemical Society-certified – may be used.
        • All equipment to be clean, properly maintained, and used appropriately
        • A Master Formulation Record and Compounding Record to be prepared
        • A Beyond-Use Date to be assigned
        • The preparation to be appropriately labeled | Label to note the final concentration of ethanol or isopropyl alcohol 

        The following are three formulations for compounding alcohol-based hand sanitizers. Formulation 1 and 2 were developed based on WHO recommendations.

        Formulation 1: Ethanol Antiseptic 80% Topical Solution

        Prepare Ethanol Antiseptic Topical Solution containing ethanol 80% (v/v) as follows (see Pharmaceutical Compounding—
        Nonsterile Preparations <795>).

        • Ethanol 96% 8333 mL
        • Hydrogen Peroxide 3% 417 mL
        • Glycerol 98% 145 mL
        • Water, a sufficient quantity to make 10000 mL | Water may be distilled water, cold boiled potable water, reverse osmosis water, or filtered water

        Measure the quantities of Ethanol, Hydrogen Peroxide, and Glycerol in suitable containers. Transfer the Ethanol and Hydrogen Peroxide into a suitable calibrated container and mix gently. Transfer the Glycerol stepwise and quantitatively into the calibrated container and mix gently after each addition. Rinse the container containing glycerol several times with water and add the contents to the calibrated container. Add sufficient Water to bring to final volume. Mix well. Transfer the solution into suitable containers.

        • Packaging and Storage: Package in suitable containers and store at controlled room temperature.
        • Labeling: Label to state for external use only, the percentage of ethanol, and the Beyond-Use Date.
        • Beyond-Use Date: NMT 30 days after the date on which it was compounded, when stored at controlled room temperature. 

        Formulation 2: Isopropyl Alcohol Antiseptic 75% Topical Solution

        Prepare Isopropyl Alcohol Antiseptic Topical Solution containing isopropyl alcohol 75% (v/v) as follows (see Pharmaceutical Compounding—Nonsterile Preparations <795>)

        Measure the quantities of Isopropyl Alcohol, Hydrogen Peroxide, and Glycerol in suitable containers. Transfer the Isopropyl Alcohol and Hydrogen Peroxide into a suitable calibrated container and mix gently. Transfer the Glycerol stepwise and quantitatively into the calibrated container. Mix gently after each addition. Rinse the container containing glycerol several times with Water and add the contents to the calibrated container. Add sufficient Water to bring to final volume. Mix well. Transfer the solution into suitable containers.

        • Packaging and Storage: Package in suitable containers and store at controlled room temperature.
        • Labeling: Label to state for external use only, the percentage of isopropyl alcohol, and the Beyond-Use Date.
        • Beyond-Use Date: NMT 30 days after the date on which it was compounded, when stored at controlled room temperature.

        Formulation 3: Isopropyl Alcohol Antiseptic 60% Topical Solution

        Prepare Isopropyl Alcohol Antiseptic Topical Solution containing isopropyl alcohol 60% (v/v) as follows (see Pharmaceutical Compounding—Nonsterile Preparations <795>).

        Measure the quantities of Isopropyl Alcohol, Hydrogen Peroxide, and Glycerol in suitable containers. Transfer the Isopropyl Alcohol and Hydrogen Peroxide into a suitable calibrated container and mix gently. Transfer the Glycerol stepwise and quantitatively into the calibrated container. Mix gently after each addition. Rinse the container containing glycerol several times with Water and add the contents to the calibrated container. Add sufficient Water to bring to final volume. Mix well. Transfer the solution into suitable containers.

        • Packaging and Storage: Package in suitable containers and store at controlled room temperature.
        • Labeling: Label to state for external use only, the percentage of isopropyl alcohol, and the Beyond-Use Date.
        • Beyond-Use Date: NMT 30 days after the date on which it was compounded, when stored at controlled room temperature.

        Antiviral treatment is recommended as early as possible for any patient with confirmed or suspected influenza who: 

        • is hospitalized;
        • has severe, complicated, or progressive illness; or
        • is at higher risk for influenza complications.

        Decisions about starting antiviral treatment should not wait for laboratory confirmation of influenza. For outpatients with acute uncomplicated influenza, oral oseltamivir, inhaled zanamivir, intravenous peramivir, or oral baloxavir may be used for treatment. For patients with severe or complicated illness with suspected or confirmed influenza (e.g., pneumonia, or exacerbation of underlying chronic medical condition) who are not hospitalized, antiviral treatment with oral or enterically-administered oseltamivir is recommended as soon as possible. Read more here.

        ADA Height For Hand Sanitizers And Soap Dispensers

        ADA Requirements for Soap Dispensers. The American Disabilities Act (ADA) was signed into law in 1990 and requires facilities to make accommodations for disabled people. Soap dispensers should not be placed higher than 44 inches if the reach depth (counter) is more than 20 inches but not more than 25 inches in depth. Read more here

        Glycerol Inactivates Viruses

        Effect of glycerol on intracellular virus survival: implications for the clinical use of glycerol-preserved cadaver skin. 

        Glycerol has long been used for the preservation of skin allografts. The antimicrobial activity of glycerol has not been fully documented. This paper reports the results of an investigation of a model studying the effect of glycerol on the inactivation of intracellular viruses. Two viruses--herpes simplex type I (HSV-1) and poliovirus--were cultured within human dermal fibroblasts. These intracellular viruses were incubated with 50 per cent, 85 per cent and 98 per cent glycerol at 4 degrees C and 20 degrees C for 4 weeks. Each week, the cultures in glycerol and controls in fibroblast maintenance medium were assayed for virus infectivity by examining the ability of harvested viruses to infect further fibroblasts. At 4 degrees C, 85 per cent glycerol could not fully inactivate intracellular HSV-I or poliovirus even after 4 weeks; 98 per cent glycerol inactivated intracellular HSV-I (after 3 weeks) but could not fully inactivate intracellular poliovirus after 4 weeks. At 20 degrees C, 85 per cent glycerol inactivated intracellular HSV-I (within 1 week) but could not fully inactivate intracellular poliovirus after 4 weeks; 98 per cent glycerol inactivated intracellular HSV-I (within 1 week) and inactivated intracellular poliovirus (after 2 weeks). It is suggested that, on the basis of this study, glycerol can reduce intracellular virus infectivity but that its effects are very dependent on concentration, time and temperature such that we would recommend that allograft skin be exposed to 98 per cent glycerol for a minimum of at least 4 weeks at a minimum temperature of 20 degrees C before clinical use.

        Monolaurin, also known as glycerol monolaurate (GML), glyceryl laurate or 1-lauroyl-glycerol, is a monoglyceride. It is the mono-ester formed from glycerol and lauric acid. Monolaurin is known to inactivate lipid-coated viruses by binding to the lipid-protein envelope of the virus, thereby preventing it from attaching and entering host cells, making infection and replication impossible. Other studies show that Monolaurin disintegrates the protective viral envelope, killing the virus.Monolaurin has been studied to inactivate many pathogens including Herpes simplex virus and Chlamydia trachomatis. Read more here.

         

        U.S. Distilleries Buy Ethanol, Glycerin And Hydrogen Peroxide At LabAlley.com To Make Hand Sanitizers And Handrub Formulations

        March 23, 2020

        Sales of hand sanitizers in the U.S. are way up. These products are becoming scarce in the face of the growing COVID-19 outbreak. Download the World Health Organization's recipe for recommended handrub formulations here

        Distilleries in the U.S. purchase alcohol and ethanol at LabAlley.com to produce a 160-proof clear spirit to use as a hand sanitizer. Get a complete list of distilleries (Including Anheuser-Busch) making hand sanitizers instead of spirits here.  Anheuser-Busch and distilleries are racing to make hand sanitizers amid the Coronavirus pandemic.

        American distilleries are assisting their communities by producing their own hand sanitizer using a recipe from the World Health Organization. The recipe "starts with ethanol, which is what we have plenty of in the distillery, then you add glycerin, hydrogen peroxide water and you mix it up," Scott Jendrek, owner of Patapsco Distilling Co. in Sykesville, Maryland, told a local NBC News affiliate.

         

        Antiviral Products For Sale Online

        A virus is a small infectious agent that replicates only inside the living cells of an organism. Several new antiviral compounds and potent and selective antiviral agents against herpes virus infections have been developed. Viruses can infect all types of life forms, from animals and plants to microorganisms, including bacteria and archaea.

        Viruses are very tiny germs made of genetic material inside of a protein coating. Viral infections play a key role in human diseases. Quercetin, morin, rutin, taxifolin, dihydrofisetin, leucocyanidin, pelargonidin chloride, apigenin, catechin, hesperidin, and naringin have been reported to possess antiviral activity against some of 11 types of viruses.

        Because lots of viruses lack efficient antiviral therapies and preventive vaccines, antiviral compounds sold at LabAlley.com, such as Quinine Sulfate and Benzalkonium Chloride are used medicinally because of their antiviral effect

        Because viruses use vital metabolic pathways within host cells to replicate, they are difficult to eliminate without using drugs that cause toxic effects to host cells in general. The most effective medical approaches to viral diseases are vaccinations to provide immunity to infection, and antiviral drugs that selectively interfere with viral replication.

        Phenolic compounds are derived from the secondary plant metabolism, although they can also be obtained by synthetic processes. Many studies have shown a great range of pharmacological effects for these substances, including vasodilatation, antiallergenic, antiinflammatory and antiviral properties, among others.

        Antiviral drugs are used in the U.S. to treat viral infections rather than bacterial infections. Buy antiviral phenolic compounds at LabAlley.com for disinfection, food and medicinal uses here.

        Hospitals in the United States by hospital grade disinfectants and antiviral cleaning chemicals such as hydrogen peroxide, isopropyl alcohol, 100% alcohol, 95% alcohol and 70% alcohol at LabAlley.com. American consumers, businesses and healthcare facilities buy supplies and chemical ingredients to manufacture Coronavirus infection protection products here.

        U.S. firms buy chemical substances and antiviral substances online at LabAlley.com to manufacture antiviral agents which inhibit production of viruses that cause disease. Food manufacturing facilities order hydrochloric acid and ascorbic acid to kill viruses. Acidic ozone water made with hydrochloric acid can deactivate H1N1 viruses very effectively. Agricultural and botanical businesses in the U.S. buy chemical supplies from LabAlley.com to make medicinal oils and tinctures that kill viruses. Home-based cosmetic manufacturers order antiviral substances such as trichloroacetic acid to make skin care products and personal care products.

        A number of different organic acids sold online at LabAlley.com produce residual antirhinoviral activity. Salicylic acid, fumaric acid, and benzoic acid produced at least a 2-log reduction in viral titersHydrogen peroxide sold online at LabAlley.com is antiviral, antibacterial and anti-fungal. Hospitals frequently order this product for virus inactivation processes. H2O2 is a convenient means for virus inactivation.

         

        Types Of Antiviral Products Sold Online At LabAlley.com

         

        About EPA Approved Disinfectants

         

        Coronavirus (COVID-19) Update: FDA Provides Guidance On Production Of Alcohol-Based Hand Sanitizer To Help Boost Supply, Protect Public Health
        March 20, 2020

        As part of the U.S. Food and Drug Administration’s ongoing commitment to address the coronavirus (COVID-19) pandemic, the agency has issued two guidance documents to communicate its policy for the temporary manufacture of certain alcohol-based hand sanitizer products. These guidance documents will be in effect for the duration of the public health emergency declared by the Secretary of Health and Human Services (HHS) on January 31, 2020.

        “We are aware of significant supply disruptions for alcohol-based hand sanitizers. Many manufacturers make hand sanitizers, and several have indicated that they are working to increase supply,” said FDA Commissioner Stephen M. Hahn, M.D. “In the meantime, these guidances provide flexibility to help meet demand during this outbreak. We will continue to work with manufacturers, compounders, state boards of pharmacy and the public to increase the supply of alcohol-based hand sanitizer available to Americans.”

        Because of an increased demand for alcohol-based hand sanitizers during the COVID-19 pandemic, there have been reports of some consumers attempting to make hand sanitizers for personal use. The agency lacks information on the methods being used to prepare such products and whether they are safe for use on human skin.

        The guidance Temporary Policy for Preparation of Certain Alcohol-Based Hand Sanitizer Products During the Public Health Emergency (COVID-19), is immediately in effect and outlines that the agency does not intend to take action against manufacturing firms that prepare alcohol-based hand sanitizers for consumer use and for use as health care personnel hand rubs during this ongoing public health emergency as described in the guidance .

        The second guidance, Policy for Temporary Compounding of Certain Alcohol-Based Hand Sanitizer Products During the Public Health Emergency, is in effect for the temporary compounding of certain alcohol-based hand sanitizers by pharmacists in state-licensed pharmacies or federal facilities and registered outsourcing facilities. Compounding is generally a practice in which a licensed pharmacist, a licensed physician, or, in the case of an outsourcing facility, a person under the supervision of a licensed pharmacist, combines, mixes, or alters ingredients of a drug to create a tailor-made medication. The temporary policy outlined by the agency does not require compounders to obtain a patient-specific prescription.

        The FDA’s guidance documents apply only to handrub products prepared using the United States Pharmacopoeia or Food Chemical Codex grade ingredients specifically described in the guidance, consistent with World Health Organization recommendations. The guidance documents also discuss product labeling and certain manufacturing methods and reporting requirements, such as that manufacturers must have a way to accept and submit adverse event reports to FDA for any products they manufacture.

        The agency realizes that manufacturers and compounders will need time to ramp up production as they obtain the ingredients needed to make these hand sanitizers. During this time the FDA will work to assist them as they develop hand sanitizers to make available for the American public.

        The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation's food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.

         

        Buy Chemical Compounds, Excipients, Powders And Pharmaceutical Manufacturing Substances From LabAlley.com To Develop And Produce Antiviral Drugs (Antiviral Agents) 

         

        Most of the antiviral drugs and antiviral agents now available are designed to help deal with HIV, herpes viruses, the hepatitis B and C viruses, and influenza A and B viruses. Researchers are working to extend the range of antivirals to other families of pathogens. Antibiotic drugs are often classified by their spectrum of activity. These classifications include antibacterial medications, antifungal drugs, antimycobacterial drugs, antiparasitic/antiprotozoal/anthelminthic drugs and antiviral formulations. LabAlley sells chemicals and supplies used to manufacture antiviral medications. 

        Viruses consist of a genome and sometimes a few enzymes stored in a capsule made of protein (called a capsid), and sometimes covered with a lipid layer (sometimes called an 'envelope'). Viruses cannot reproduce on their own, and instead propagate by subjugating a host cell to produce copies of themselves, thus producing the next generation. Researchers working on such "rational drug design" strategies for developing antivirals have tried to attack viruses at every stage of their life cycles

        Antiviral drugs are a class of medication used specifically for treating viral infections rather than bacterial ones. Most antivirals are used for specific viral infections, while a broad-spectrum antiviral is effective against a wide range of viruses. Unlike most antibiotics, antiviral drugs do not destroy their target pathogen; instead they inhibit their development.

        Viruses represent a large group of infective agents that are composed of a core of nucleic acids, either RNA or DNA, surrounded by a layer of protein. They are not really living organisms according to general understanding, since they lack the cell membrane that is associated with living cells. Viruses can reproduce only inside a living cell, and they cause many diseases. Viruses are not normally affected by antibiotics but a small number of viruses can either be destroyed or have their growth stopped by antiviral drugs.

        Lab Alley sells lab equipment, chemical compounds, reagents, scientific instruments and laboratory supplies to drug manufacturing companies and pharmaceutical firms. Lab Alley customers synthesize antiviral drugs and produce pharmaceutical formulations through various processes which include milling, powder blending, granulation, coating, hot metal extrusion, tablet pressing and others. Pharmaceutical formulation, in pharmaceutics, is the process in which different chemical substances, including the active drug, are combined to produce a final medicinal product. The word formulation is often used in a way that includes dosage form.

        Common chemicals purchased online at LabAlley.com by antiviral drug manufacturers include solvents used for extraction. Lab Alley also sells excipients and chemicals in powder form that are used in the pharmaceutical industry. Common excipients purchased online at LabAlley.com by pharmaceutical manufacturing enterprises include starch, cellulose, alginates, silicon, silica compounds, stearic acid and magnesium stearate. Antiviral drug manufacturing operations and pharmaceutical companies in the U.S. purchase chemicals in a powdered, crystal, flake or crystalline form online at LabAlley.com.

         

        Antiviral Wipes, Sprays And Soaps

        Clorox wipes kill bacteria and viruses, and I don't have to wash after using them. Quote: Clorox Disinfecting Wipes kill 99.9% of viruses and bacteria, including cold and flu, E. Coli, Salmonella, Staph, and Strep. Read more here. Buy Conzerol Antiviral Molluscum Treatment Soap, here. Anti-viral disinfectant sprays help to stop the spread of bacterial and viral diseases such as PMV and Newcastle Disease.

         

        Is Ethanol A Disinfectant?

        Ethanol (ethyl alcohol, C2H5OH) and 2-propanol (isopropyl alcohol, (CH3)2CHOH) have similar disinfectant properties. They are active against vegetative bacteria, fungi, and lipid-containing viruses but not against spores. Their action on non-lipid-containing viruses is variable. Read more here. Learn about the viral activity of 70% ethanol vs enveloped and non-enveloped viruses, here.

         

        Isopropyl Alcohol vs Ethanol

        These two alcohols are the same actually when it comes to disinfectant properties. However, they have slight differences when it rubbed on the skin. Ethanol is the type of alcohol present in alcoholic beverages. Isopropyl alcohol is also known as isopropanol, 2-propanol or rubbing alcohol. Read more here.

         

        Antiviral Activity Of Alcohol For Surface Disinfection

        Bacteria and viruses from the patient's mouth travel with dental splatter and spills. A surface disinfectant should possess antiviral activity as well as antibacterial action. Because of frequent and 'open' application in the dental office, such a disinfectant should be non-toxic, non-allergenic and safe for the hygienist. It now appears that high-concentration alcohol mixtures (i.e. 80% ethanol + 5% isopropanol) are not only excellent antibacterials, but quickly inactivate HIV as well as hepatitis B and hepatitis C viruses. Compared to alternative surface disinfectants, use of high-concentration alcohol for the spray-wipe-spray method of surface disinfection in dentistry appears safe and efficient. However, dried matter should be wiped and hydrated first. Read more here.

         

        Use Benzalkonium Chloride To Inactivate Viruses

        Benzalkonium chloride (as Roccal or Zephiran) was found to inactivate influenza, measles, canine distemper, rabies, fowl laryngotracheitis, vaccinia, Semliki Forest, feline pneumonitis, meningopneumonitis, and herpes simplex viruses after 10 minutes of exposure at 30 C or at room temperature. Read more here

        Type A influenza viIrus was inactivated by concentrations of benzalkoniunm chloride as low as 0.025 mng/iml. Measles and canine distemper viruses were also sensitive to the quaternary. Feline pneuiinonitis and miieningopneumionitis agents were inactivated by benzalkonium chloride after 10 minutes of exposure at room temperature. Rabies, fowl laryngotracheitis, Seliliki Forest, and herpes simplex viruses were rapidly inactivated by low concentrations of benzalkonium chloride. Review more information on the virucidal activity of benzalkonium chloride for 13 viruses here.

         

        Benzalkonium Chloride Disinfectant

        Benzalkonium chloride is widely used as a preservative in eyedrops; in higher concentrations it is used as an antiseptic and disinfectant. Read more here.

         

        Antiviral Phenolic Compounds And Phenolic Household Disinfectant Ingredients For Sale Online At LabAlley.com

         

        Phenolics are active ingredients in some household disinfectants. Phenolic compounds, have been studied extensively (biologically and chemically) due to their extensive antiviral activities. Learn about the cytotoxic, antiviral properties and anti-HSV-1 activities of phenolic compounds here. They are also found in some mouthwashes and in disinfectant soap and handwashes. Phenol is probably the oldest known disinfectant as it was first used by Joseph Lister (pioneer of antiseptic surgery), when it was called carbolic acid.

        Phenol is also called carbolic acid, hydroxybenzene, oxybenzene, phenylic acid. a white, crystalline, water-soluble, poisonous mass, C6H5OH, obtained from coal tar, or a hydroxyl derivative of benzene: used chiefly as a disinfectant, as an antiseptic, and in organic synthesis.

        Phenols are widely used in household products and as intermediates for industrial synthesis. For example, phenol itself is used (in low concentrations) as a disinfectant in household cleaners and in mouthwash. Phenol may have been the first surgical antiseptic. Read more here.

        Phenol is an aromatic organic compound with the molecular formula C6H5OH. It is a white crystalline solid that is volatile. The molecule consists of a phenyl group (−C6H5) bonded to a hydroxy group (−OH). Mildly acidic, it requires careful handling because it can cause chemical burns. Read more here.

         

        Buy Antiviral Phenolic Compounds Online At LabAlley.com

        Phenolics are active ingredients in some household disinfectants. They are also found in some mouthwashes and in disinfectant soap and hand washes. Phenol (carbolic acid) is one of the oldest antiseptic agents. Phenol has good penetrating power into organic matter and is mainly used for disinfection of equipment or organic materials that are to be destroyed (eg, infected food and excreta).

         

        Why You Shouldn't Make Your Own Hand Sanitizer
        Written By Sarah Mitroff | Published On March 24, 2020 By CNET

        It's easy to mess up making DIY hand sanitizer, so do this instead.

        The rapid spread of coronavirus (or COVID-19) has people clearing out shelves of hand sanitizer across the US. And if you try to buy it online, good luck -- most of it is out of stock or marked up on Amazon, Walmart.com, Bath and Body Works, Walgreens and other retailers. Target and regional grocery store Kroger now have limits on how many "anti-viral" products you can purchase at a time. And, New York Governor Andrew Cuomo announced that New York state will be producing its own hand sanitizer to address the shortages and price gouging.

        The shortages and buying limits have spurred people to make their own hand sanitizer using recipes from Twitter, Reddit, Pinterest, countless blogs and even a pharmacy. But just because these recipes exist doesn't mean you should follow them.

        Recipe For Hand Sanitizer On YouTube 

        What you'll need: 

        • 91% Isopropyl alcohol (rubbing alcohol)
        • Aloe vera gel
        • Mixing bowl
        • Spoon or something for whisking
        • Small container, such as a 3 oz. travel bottle
        • Optional: essential oil to give the liquid a fragrance

        Directions: 

        • In a mixing bowl, stir Isopropyl alcohol and aloe vera gel together until well blended.
        • Add 8-10 drops of scented essential oil (optional, but nice!). Stir to incorporate.
        • Pour the homemade hand sanitizer into an empty container and seal. Write “hand sanitizer” on a piece of masking tape and affix to the bottle.


        Reasons To Not Make Your Own Hand Sanitizer

        First, the Centers of Disease Control recommends washing your hands over using hand sanitizer, unless you don't have access to soap and water. Second, the FDA has said that it knows people are making DIY hand sanitizer at home, but that it doesn't have any "verifiable information on the methods being used to prepare such products and whether they are safe for use on human skin."

        Lastly, experts caution that making homemade hand sanitizer is harder than it seems. If you don't get the concentration right, experts warn that you'll end up with something that isn't effective or is too harsh, and is a waste of ingredients.

        The key is to get the right ratio of ingredients. The CDC Control recommends using a hand sanitizer that contains at least 60% alcohol, which store-bought hand sanitizers have. But trying to replicate that on your own can be tricky, Dr. Sally Bloomfield, with the London School of Hygiene and Tropical Medicine told the Guardian.

        In the video below, Dr. Jason Kindrachuk, an assistant professor of Viral Pathogenesis at the University of Manitoba explains that you're better off using soap than trying to make your own hand sanitizer.

         


        Official Hand Sanitizer Formulas 

        Both the World Health Organization and the FDA have guidelines for making hand rubs (the agencies' term for hand sanitizer), but they are designed for medical professionals, not the average consumer. The WHO's official instructions call for denatured alcohol or isopropyl alcohol, glycerol (also known as glycerin), hydrogen peroxide and sterile water. You must measure the concentration of alcohol in the final product using an alcoholometer to ensure it is effective at killing germs and safe to use.

        The recipe also does not recommend including any dyes, essential oils or other fragrances because they could cause an allergic response -- a lot of DIY recipes call for essential oils to mask the smell of alcohol.

        On March 20, 2020, the FDA released its temporary guidelines for pharmacists and other manufacturers to make hand sanitizer. Under its recommendation, you must use pharmacy-grade ingredients, test the alcohol level in the final product, and label the finished formula. The FDA recommends the WHO's formula, and echoes that adding additional active or inactive ingredients (such as aloe vera gel or essential oils) "may impact the quality and potency of the product."

        The FDA also notes that it is "aware of reports that some consumers are producing hand sanitizers for personal use; the Agency lacks information on the methods being used to prepare such products and whether they are safe for use on human skin." Unless you can follow the instructions outline by the WHO, making your own hand sanitizer just isn't smart for your own safety.

        Homemade Hand Sanitizer Recipes 

        Most of the countless recipes out there use a mix of 91% or 99% isopropyl alcohol (also known as rubbing alcohol) and aloe vera gel, which is necessary to add moisture to your skin because alcohol will dry it out. In these recipes, the typical ratio is two thirds rubbing alcohol to one third of a cup of aloe vera gel.

        Even if you follow that recipe, you can still mess it up. Mixing it at home, you can't control how the alcohol gets diluted in the final product. If you don't use enough aloe gel, it will dry out the skin on your hands, which can cause it to crack or bleed (the same is true if you just pour rubbing alcohol on your skin).

        But if you don't use enough alcohol, the final product won't be as effective at killing germs as store-bought hand sanitizer -- rendering it basically useless according to some experts. You can also contaminate your batch with bacteria by not using clean tools to mix it together.

        The final issue is that because of the popularity of these homemade hand sanitizers, the ingredients are now harder to come by. So even if you want to make it, you might not be able to find rubbing alcohol and aloe vera at your local drugstore.

        You should avoid recipes that call for vodka or spirits because you need a high proof liquor to get the right concentration of alcohol by volume. That's because most liquor is mixed with water, so if you mix a 80-proof vodka (which is the standard proof) with aloe, you'll have hand sanitizer that contains less than 40% alcohol. In response to a tweet about someone using Tito's Vodka to make DIY hand sanitizer, the company responded by saying that you shouldn't use its product for that purpose.

         



        So What Should You Do Instead? 

        Wash your hands. The CDC and WHO both agree that's the best thing you can do right now to protect yourself from getting sick, either from coronavirus or anything else. Wash your hands with soap and water for 20 seconds, many times per day -- after you use the restroom, before and after you eat, before and after you prepare food and in many other scenarios.

        Also avoid touching your face in general, but especially with dirty hands. Most everything you touch throughout the day is covered in germs and if you touch your mucous membranes (lips, noise, eyes) you can spread viruses and bacteria into your own body.

        If you want to use other disinfecting products to clean your hands or surfaces, the Environmental Protection Agency released a full list of products that can kill the virus.

        I don't advise it, but if you're determined to make your own hand sanitizer (and can actually find the ingredients to do so), avoid any recipes that don't use at least 60% alcohol. Otherwise, just wash your damn hands.

        Whiskey Producers Are Making Hand Sanitizer. Here's How They Organized.
        Written By Maggie Kimberl | Published By Entrepreneur Media, Inc. On March 24, 2020

        With loosened laws and a lot of experimentation, the industry has stepped up to fill a critical need.

        The world needs hand sanitizer — far more than the existing hand sanitizer industry can produce. So the American whiskey industry, along with other alcohol industries like craft breweries, have begun stepping up. They’re hitting pause on making beverages, and have begun making the alcohol-based sanitizers that save lives.

        It’s an important example of how entrepreneurs can pivot and contribute to the fight against Covid-19. And it contains important lessons for other entrepreneurs on how to do the same.

        Lift Regulations

        In a way, the American whiskey industry was already primed for this work. Back in 1941, after the attack on Pearl Harbor, the American government assumed control of the distilling industry and converted many of the stills to produce high-proof ethanol. This ethanol was used for antifreeze, munitions, octane boosters, lacquer, synthetic rubber and more.

        Today, no government mandate was required — but government help was. When the COVID-19 crisis first hit, some of the smaller distilleries began trying to share their alcohol; any whiskey manufacturer will have parts of the distillate that can’t be used in beverages but could become a general-purpose cleaner. However, laws stood in their way. Strict regulations control what can and can’t happen in a distillery, and these businesses are heavily taxed. With these laws in place, the distilleries couldn’t be helpful.

        The industry started raising its voice, and policy-makers responded. Local, state and even federal laws were lifted or altered. On March 18, the Alcohol and Tobacco Tax and Trade Bureau, which oversees the industry, also cleared a path: It waived parts of a law, including requirements that distilleries obtain permits or bonds to produce hand sanitizer. Now distilleries could finally get to work.

        Create Many Different Solutions 

        Each distillery has taken a somewhat different path. Some distilleries chose to make sanitizing products, and then provide them for free to first responders and critical facilities and businesses. Others have chosen to sell their sanitizing products to the public, as a way to keep their staffs paid.

        In Kentucky, the response from the bourbon industry has been swift and decisive. Brown-Forman, one of the largest American-owned spirits manufacturers, started delivering free sanitizer to first responders in Woodford County, the location of its Woodford Reserve distillery. (Its Old Forester Distillery in Louisville, Kentucky will follow suit.) The Neeley Family Distillery is making small batches of hand sanitizer and allowing people to bring their own bottles to fill up for a donation to cover the costs. Lexington Brewing & Distilling, Rabbit Hole Distillery and Wilderness Trail Distillery have all announced efforts to produce hand sanitizer as well.

        Outside of Kentucky, many small distilleries are doing the same — including Smooth Ambler in West Virginia, Koval Distillery in Chicago, Corsair Distillery in Tennessee, American Craft Whiskey Distillery in California and Whisky Acres Distilling in Illinois. 

        Share Information Among Competitors

        But there’s a problem: Just because a distiller can make whiskey, that doesn’t mean they know how to make alcohol for hand sanitizer. To make it work, the industry has come together to share information — producing webinars, online guides, and more. Distilleries are modifying their equipment and learning on the fly.

        At Catoctin Creek Distillery in Virginia, Distiller Becky Harris says she’s working closely with the American Craft Spirits Association (ASCA), with daily meetings to devise the best possible course of action for distillers wanting to produce hand sanitizer. At one point, her husband and business partner, Scott Harris, was receiving 50 emails every hour from people asking about hand sanitizer. She says the media attention on this topic has been helpful, because it has shown regulatory bodies there is a huge surge in demand for these products, which in turn enabled the ASCA to streamline and expedite the process of building guidelines and finding supply in the supply chain.

        As the situation evolves, distilleries are also having to change their plans. In Michigan, for example, the Traverse City Whiskey Company originally wanted to sell hand sanitizer to the public — but then its inventory of 10,000 units sold out overnight. “The response and demand has been shocking,” says Chris Fredrickson, the company’s co-founder. “Because of this, we've evolved our strategy from retail to include medical and first responders, as that has been the greatest need.”

        What will come next? Nobody knows, of course — but more distilleries join the effort to produce hand sanitizer, and owners say they’ll look for even more ways to band together and support people in the industry. “I would say that whiskey drinkers are the most generous people on the planet,” says Bill Thomas, owner of the Jack Rose Dining Saloon in Washington D.C., who I spoke with recently for American Whiskey Magazine. “And this is absolutely proof that the whiskey drinker is the best kind of human being on the planet.”

        It’s also a lesson for other industries during this difficult time: With loosening regulations, you can collaborate with your peers on new innovations ... and start solving any problem you can.

        Recipe For Hand Sanitizer Using Witch Hazel | Ingredients

        • 2 ounce spray bottle
        • 5 drops vitamin E oil (optional, this makes for soft hands!)
        • 3 tablespoons witch hazel with aloe vera, vodka, or 190 proof grain alcohol (Everclear), see notes
        • 5 drops lemon essential oil
        • 5 drops orange essential oil
        • 5 drops tea tree essential oil. 

        Recipe For Hand Sanitizer With Vodka

        Why you shouldn’t use Tito’s Vodka to make hand sanitizer — or attempt to make your own hand sanitizer period. Hand sanitizer is selling out in stores over coronavirus fears, but doctors say you’re better off washing your hands. But some misinformed individuals have also been looking into making sanitizers with liquor, such as Everclear grain alcohol and Tito’s Handmade Vodka. Read more here

        Alcohol is the gold standard for anti-microbial action—there is a reason most store-bought hand sanitizers are alcohol-based. One option is to use vodka. Most vodka on store shelves is around 40-45% alcohol (80-90 proof), and then gets further diluted in this recipe. This is what we consider a “middle of the road” hand sanitizer. The vodka does make this version slightly drying to the hands.

        3M™ Disinfectant Concentrates and U.S. EPA Emerging Pathogen Policy

        Due to the 2019-nCoV being a newly emerging pathogen there is no U.S. EPA registered disinfectant currently available on the market with the 2019-nCoV efficacy claim specifically listed on their container label. The U.S. EPA Emerging Pathogen Policy allows for professional judgments on effectiveness of disinfectants with current registrations with similar, representative microorganism families based on their cell structures. A person with the appropriate knowledge and technical skills to analyze such information can make a determination based on published information on disinfectant cleaners that meet the U.S. EPA Emerging Pathogen Policy for use on non-critical, hard, non-porous surfaces as defined by U.S. EPA. The following products are U.S. EPA-registered 3M disinfectants that meet U.S. EPA’s Emerging Pathogen Policy.

        EPA Registered, Quaternary Disinfectant Cleaners | Kills HIV-1, Hepatitis B Virus (HBV), MRSA, VRE, KPC, Rotavirus, Acinetobacter, VRE, Herpes Simplex I And Other Pathogens

        EcoLab Virasept Surface Disinfectant Cleaner

        According to the company, Virasept is a patented ready-to-use, one-step detergent-disinfectant, virucide, bactericide, tuberculocide, fungicide, and sporicide that effectively cleans, disinfects, and deodorizes. It won't harm fixtures and is formulated for daily use. Buy it online at Walmart.com.

        US IPA Prices Soar On Rising Global Demand And Supply Shortage
        Author: Deniz Koray | Published By ICIS On March 19, 2020
        Posted Here On March 27, 2020

        HOUSTON (ICIS)--US isopropanol (IPA) prices surged this week on heavy demand for hand sanitizer during the coronavirus (Covid-19) crisis, and there are no quick fixes for either the strong demand or the shortages of product. While European prices had risen to even higher numbers in the past month, US increases had been modest. However, prices surged this week, as domestic IPA spot prices are now assessed at 62-85 cents/lb ($1,367-1,874/tonne) FOB (free on board) US Gulf. IPA prices DEL (delivered) to the US Gulf are assessed at 64-90 cents/lb. 

        DOMESTIC IPA MARKETS
        Until this week, prices in the US were increasing at much smaller rates than in Europe, generally in the range of 5 cents/lb or less. However, this week was a tipping point for the domestic market, as the US response to the coronavirus was heightened. Isopropyl alcohol is used in many hand sanitizers, which are in high demand among consumers because of their ability to kill germs. Hand sanitizers were among the first products to sell out at grocery stores and pharmacies, but demand has increased since then. It was believed that the US was not seeing the level of IPA price increases as in Europe since it had more ethanol. However, due to the increase in US exports to Europe as well as the rapid rise domestic demand, supply of IPA was nevertheless overwhelmed. One market participant said many producers were on sales allocations, but this could not be confirmed.

        EXPORT MARKETS
        Last week, an export deal for Europe was heard at $1,350/tonne (61.24 cents/lb) CFR (cost and freight) Europe. Another was heard at $1,700/tonne CFR Europe. This week, prices for individual deals were heard for up to triple these numbers in Europe on imported IPA. However, these are not yet considered representative for the market. According to a market source, prices of exports to Asia in the past several days doubled, while another market participant said that Latin American demand began to heavily increase this week, but that there was almost no supply to provide to buyers there. Export prices now range from 57.52-95.00 cents/lb, although much higher individual spot prices were heard. IPA is a solvent principally used in industrial and consumer products including cosmetics and personal-care products, paints and resins, pharmaceuticals, food, inks and adhesives. It is also used in de-icers in the winter. US IPA suppliers include ExxonMobil, Dow Chemical, LyondellBasell, Monument Chemical and Shell Chemical.

        Ethanol Plants Seek Rule Changes To Resupply Hand Sanitizer
        By David Pitt Associated Press March 26, 2020

        Hospitals and nursing homes are desperately searching for hand sanitizer amid the coronavirus outbreak and the ethanol industry is ready to step in to provide the alcohol, a key ingredient.

        DES MOINES, Iowa -- As hospitals and nursing homes desperately search for hand sanitizer amid the coronavirus outbreak, federal regulators are preventing ethanol producers from providing millions of gallons of alcohol that could be transformed into the germ-killing mixture. The U.S. Food and Drug Administration's roadblock has been frustrating the health care and ethanol industries, which have been calling for a relaxed regulation to deal with the public health care emergency. “Hand sanitizer is a big part of our lives,” said Eric Barber, CEO of Mary Lanning Healthcare, a hospital in Hastings, Nebraska. “We can’t get any. We order it and it’s just not available.” The problem for the ethanol industry is that most plants make food-grade ethanol, one step below the highest pharmaceutical grade. But since the plants aren't certified to comply with stringent production standards designed to protect quality of medicines, food ingredients and dietary supplements, the FDA doesn't want the alcohol used for a product to be applied to the skin. In addition, the alcohol is not denatured or mixed with a bitter additive to make it undrinkable. The FDA insists this step is “critical” because of cases of poisoning, sometimes fatal, among young children who have accidentally ingested hand sanitizers. An FDA spokesman said Thursday that regulators have already seen a rise in poisonings linked to hand sanitizers in recent weeks, “heightening this public concern.” The FDA is also skeptical of industry claims that undenatured sanitizers could be distributed in a way that would keep them away from children. “It is unclear what, if any, measure could be instituted to ensure that the product does not make its way into consumer hands, where children could have access,” FDA’s Jeremy Kahn said in an emailed statement. Facing a nationwide shortage, Barber said the FDA should temporarily relax regulations to allow alternative production. “You’re talking about alcohol. Does it matter if it's fuel grade or whatever the stuff is they’re trying to price gouge now? I think its common sense,” he said. “We may need to consider a range of possible solutions that were not on the table before the pandemic,” said Nancy Foster, a vice president with the group, in an emailed statement to the AP. The Consumer Brands Association, formerly the Grocery Manufacturers Association, has had conversations with the FDA to push the agency to reconsider its guidelines. The group, which represents branded food, consumer products and beverage companies, said that hand sanitizer supplies are running so low that its members have had to ration it out to workers in stores, distribution centers and manufacturing plants. "We need a temporary solution," said Mike Gruber, vice president of regulatory and technical affairs at the trade association. “This goes toward ensuring basic food safety practices.” Distillers that produce vodka, whisky and other alcoholic drinks have been given some regulatory waivers by the Alcohol and Tobacco Tax and Trade Bureau allowing them to produce hand sanitizer. Many have done that, but they produce much smaller volumes of alcohol than an ethanol plant could produce. They also receive a benefit in the Senate-passed stimulus bill. The Distilled Spirits Council of the United States, which represents dozens of large and small distillers, applauded Congress for easing taxes on distillers who make hand sanitizer. Under the stimulus package passed late Wednesday, distillers don’t have to pay federal excise taxes on alcohol used for hand sanitizer through Jan. 1, 2021. “Hundreds of U.S. distillers are stepping up to produce hand sanitizer and they should not be hit with a huge tax bill for producing this much-needed item, especially at a time when so many of them are struggling,” said Chris Swonger, the group’s president and CEO. But the council said it’s urging the FDA to update its guidance and let distillers use undenatured alcohol for hand sanitizer. The stimulus bill requires distillers to follow the FDA’s guidance if they want to receive the tax breaks. The FDA has waived dozens of regulations in recent weeks to boost production of key medical supplies, including coronavirus tests, ventilators, gloves and hand sanitizers. Under the latest FDA guidelines, regulators maintain standards for alcohol, requiring new producers to use alcohol that meets federal or international standards for use in either drugs or food products. The regulatory hurdles are especially frustrating for Midwest ethanol producers who are facing plunging fuel demand and a petroleum fight between Saudi Arabia and Russia that caused prices to plummet. The factors are forcing more plants to curtail production and close. For ethanol producers relaxed rules, including a requirement of the hard-to-acquire denaturant, would allow them to step in an help in a national emergency. “If we could get the FDA to say yes you can use the beverage grade and for the duration of this emergency at least for some point in time here for the next two weeks you can waive the denaturant we would literally have millions of gallons of hand sanitizer available within a matter of days,” said Monte Shaw, CEO of Iowa Renewable Fuels Association, an ethanol trade group. “Every one of our plants has gotten contacted by people who want this stuff and we can’t send it to them.” Andrew Vrbas owner of Pacha Soap, a boutique soap shop in Hastings, Nebraska, had just finished renovating a 100,000-square-foot former bread factory as a project to boost the community. Now, he’s preparing to set up hand sanitizer production there to supply to hospitals. He’s received calls from hospitals in Nebraska, Florida and New York City seeking hand sanitizer. “We are literally three miles from a plant that has as much ethanol as you could imagine,” he said. “We’re sitting on millions of gallons of alcohol. If we could rally the federal government to say look if you just let us work with local ethanol producers we have the expertise, we have the ability to provide hand sanitizer to hospitals not only in Nebraska but all across the country that are just reaching out through my network saying if you could send us hand sanitizer, we’re out.”

        Virus Inactivation Mechanisms: Impact of Disinfectants on Virus Function and Structural Integrity

        Oxidative processes are often harnessed as tools for pathogen disinfection. Although the pathways responsible for bacterial inactivation with various biocides are fairly well understood, virus inactivation mechanisms are often contradictory or equivocal. In this study, we provide a quantitative analysis of the total damage incurred by a model virus (bacteriophage MS2) upon inactivation induced by five common virucidal agents (heat, UV, hypochlorous acid, singlet oxygen, and chlorine dioxide). Each treatment targets one or more virus functions to achieve inactivation: UV, singlet oxygen, and hypochlorous acid treatments generally render the genome nonreplicable, whereas chlorine dioxide and heat inhibit host-cell recognition/binding. Using a combination of quantitative analytical tools, we identified unique patterns of molecular level modifications in the virus proteins or genome that lead to the inhibition of these functions and eventually inactivation. UV and chlorine treatments, for example, cause site-specific capsid protein backbone cleavage that inhibits viral genome injection into the host cell. Combined, these results will aid in developing better methods for combating waterborne and foodborne viral pathogens and further our understanding of the adaptive changes viruses undergo in response to natural and anthropogenic stressors. Read more here.

        Inactivation Of Influenza Virus By Mild Antiseptics 

        A number of antiseptics were tested for their inactivating effect upon the virus of influenza during a brief period of exposure. This was accomplished by preparing mixtures of the antiseptics and virus, allowing them to remain in contact for 3 minutes, diluting the mixtures to the point where they would not be toxic for chick embryos and then injecting the material into embryonated eggs. Survival of the embryos indicated inactivation of the virus. The following preparations were found to inactivate the virus in 3 minutes or less: phenol, 3 per cent; tincture of iodine, U.S.P. XII, 0.1 per cent; Lugol's solution, U.S.P. XII, 1 per cent; mercuric chloride, 1:1000; potassium permanganate, 1:1000; copper sulfate, 1 per cent; propylene glycol, 90 per cent; liquor antisepticus, N.F. VII, 80 per cent. Read more here.

         

        Antiviral Activity Of Lugol's Solution (Lugol's Iodine) 

        Lugol's Iodine, also known as aqueous iodine and strong iodine solution, is a solution of potassium iodide with iodine in water. Iodine products and Lugol's Iodine are sold online at LabAlley.com. Cleaning with iodine may stop the spread of virusesJean Guillaume Auguste Lugol (18 August 1786 – 16 September 1851) was a French physician. It has been know for a long time that iodine kills viruses. Povidone iodine has been used in hospitals under the brand name Betadine. BETADINE® is used for upper respiratory tract infection care.

        What Inhibits And Inactivates Viruses?

        What Does Not Kill The Coronavirus

        DIY Hand Sanitizers, Face Masks And Disinfecting Sprays | DIY Alternatives for When Stores Are Out of Coronavirus-Fighting Products
        April 4, 2020

        DIY hand sanitizers were the index species in the current wave of shelf extinctions, with usually plentiful supplies of Purell gel and similar products vanishing fast. Even without sanitizers, epidemiologists stress there is an exceedingly reliable alternative that works just as well: wash your hands with soap and water. Read more here.

        CleanSmart Disinfectant Spray Mist Kills 99.9% Of Viruses, Bacteria, Germs, Mold And Fungus

        CleanSmart Disinfectant Spray Mist leaves no chemical residue and is great to clean and sanitize CPAP masks and parts. Simply spray, no rinsing, no wiping, air dry. Safe for food contact on counters and all appliances. Free of alcohol, ammonia, bleach, fragrances and dyes. 100% safe to spray and store around children and it breaks down to saline after use. Read more here.

        Chemical Disinfection Of Virus‐Contaminated Surfaces

        Chemical disinfection is widely practiced as a means of controlling and preventing the spread of infectious diseases. Although disinfection of bacteria has been widely studied, much less attention has been paid to the virucidal potential of commonly used disinfectants in spite of the low infective dose of many human pathogenic viruses. This review considers what is known about the disinfection of viruses and the virucidal properties of different classes of disinfectant chemicals. It focuses on virus disinfection from a practical viewpoint and also critically evaluates the testing techniques currently used for examining the efficacy of disinfectant products. Read more here.

        Factors In The Selection Of Surface Disinfectants For Use In A Laboratory Animal Setting

        Because surface disinfectants are an important means of pathogen control within laboratory animal facilities, these products must have an appropriate spectrum of antimicrobial activity. However, many other factors must also be considered, including effects on human health, environmental safety, and animal behavior. Aqueous solutions of sodium hypochlorite often are considered to be the ‘gold standard’ for surface disinfection, but these products can be corrosive, caustic, and aversive in odor. Read more here.

        Virus Disinfectant Efficacy Testing Information From Microchem Laboratory 

        Virucidal Efficacy Testing Introduction

        In the United States, virucidal disinfectants used on environmental surfaces are regulated by the Environmental Protection Agency (EPA) under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). The EPA regulates disinfectants and sanitizers as pesticides, often referring to them as "antimicrobial pesticides." Before a disinfectant can be sold in the U.S. it must first be registered with the EPA, as well as with all 50 states. Currently the U.S. EPA does not recognize "virucidal sanitizers" - all virucides must meet disinfectant-grade efficacy guidelines.

        To register a virucidal disinfectant, companies must submit chemical characterization, safety, and efficacy data to the EPA, as well as pay registration fees. Efficacy data should be generated in compliance with Good Laboratory Practice Regulations (GLP). Test methods used should be taken from the Series 810 guidance, and companies should consult the EPA's Pesticide Registration Manual.

        VIRUCIDAL EFFICACY TESTING IS DIFFERENT - HERE'S HOW:
        Disinfectant Testing Basics:

        The EPA currently only recognizes "hard surface carrier" methods for substantiation of virucidal efficacy claims. These methods consist of a non-porous carrier (typically glass) being inoculated with the selected virus, dried, and then treated with the disinfectant. Virucidal hard surface carrier methods are quantitative, meaning that percent and log reductions are calculated by determining the TCID50 (50% Tissue Culture Infective Dose) per carrier before and after treatment with the disinfectant. The disinfectant must demonstrate complete inactivation of the virus down to the limit of detection of the assay, or (if cytotoxicity is observed) a ≥ 3.00 log10 reduction (99.9%).

        Observation of Results: 
        Virus testing is unique within the laboratory because the presence of viruses before and after product treatment is not determined by observing growth of virus but rather by observing the damage caused by infection to mammalian host cells. When virologists analyze individual sets of cells after a study, they use a microscope to look for where healthy cell layers become damaged. This damage is known as the cytopathic effects (CPE) of infection. The quantity and quality of CPE is used to calculate the amount of virus present.

        CPE is typically observed as changes to cell appearance and monolayer (the layer host cells form when they attach to a flask or tray) disruptions. CPE can vary depending on the virus and host cell line used. Some instances of CPE are distinct, consisting of severe monolayer disruption and cell rounding. Some CPE can be subtle, consisting of gradual enlargement of host cells that is only recognizable when compared to a negative control. In cases where CPE is difficult to distinguish, special confirmatory assays are used to verify the results of the assay. Some more common confirmatory assays include Hemagglutination Assays (HA) and immunofluorescent staining (IF).

        Study Preparation and Timeline:

        From the laboratory's perspective, a significant amount of work and time is required to grow and maintain the sterile cell cultures that are needed to propagate and detect viruses in antimicrobial efficacy studies. From our customer's point of view, the cell culture requirement means that extra time must be given to the laboratory to prepare for and execute the study. Most studies take 1-2 weeks to complete, though some can take 3-4 weeks. The behind-the-scenes cell culture work and extraordinary expertise necessary to conduct virological assays also means that virological studies are more expensive than their related bacteriological assays.

        Study Conduct and Parameters:

        There are two main viral morphologies - enveloped and non-enveloped. Non-enveloped viruses consist of genetic material surrounded by a hard protein coat. Enveloped viruses have an additional lipid layer encompassing their protein coat. The limited sensitivity of non-enveloped viral components means that these viruses can persist in an infectious state even when exposed to harsh environmental conditions - including exposure to UV or relatively high temperatures. When it comes to testing, this means that one can translate almost any bacteriological study into a non-enveloped viral assay without changing too many parameters.

        Enveloped viruses are another story. Their delicate lipid envelopes leave them vulnerable to environmental factors like osmotic pressure, low humidity, and high temperatures. When working with enveloped viruses, certain parameters (like contact times and contact temperatures) and even general study methods may need to be modified to accommodate the unique demands of these microbes.

        VIRUSES TESTED AT THE MICROCHEM LABORATORY*

        • Adenovirus 1
        • Adenovirus 2
        • Bovine Viral Diarrhea Virus (US EPA-Approved Hepatitis C Surrogate)
        • Bovine Rotavirus
        • Canine Distemper Virus
        • Canine Parainfluenza Virus
        • Canine parvovirus
        • Coronavirus (human)
        • Coxsackievirus B3
        • Coxsackievirus B6
        • Echovirus 11
        • Enterovirus 68
        • Enterovirus 71
        • Epizootic Hemorrhagic Disease Virus
        • Equine Herpesvirus 1
        • Feline Calicivirus (US EPA-Approved Norovirus Surrogate)
        • Human herpesvirus 1 (HSV1)
        • Human herpesvirus 2 (HSV2)
        • Human herpesvirus 5 (Cytomegalovirus)
        • Hepatitis A virus
        • Influenza A virus, H1N1 (human)
        • Influenza A virus, H1N1 (swine)
        • Influenza B virus
        • Measles virus
        • Minute Virus of Mice
        • MS2 Bacteriophage (Viral Screening Tool)
        • Poliovirus 1
        • Respiratory Syncytial virus (RSV)
        • Rhinovirus
        • Rotavirus (Group A)
        • Vesicular Stomatitis Virus
        • Zika Virus

        Read more here.