Buy Ingredients For Safe Recipes For DIY Homemade Hand Sanitizers

Safe Recipes For DIY Homemade Hand Sanitizers

Buy Natural Food Grade Additives, EPA-Registered Disinfectants, Pharmacy Grade Ingredients, Antiviral Chemical Compounds And Organic Raw Materials For The Safest Recipes For Hand Sanitizers | Hand Sanitizer Recipes And Antiseptic Topical Solution Recipes Are Listed Below | Hand Sanitizer Ingredient Prices And Disinfectant Ingredient Prices Are Listed Below

 

DIY Hand Sanitizer (Antiseptic Topical Solution) Recipe # 1

Homemade Hand Sanitizer (Antiseptic Topical Solution) Recipe # 2

    The Coronavirus has lead some to make their own hand sanitizer. To make hand sanitizer, you'll need just two ingredients: aloe vera gel and isopropyl alcohol. You can create your own Purell substitute at home. The active ingredient many hand sanitizer recipe is the alcohol, which needs to comprise at least 60% of the product in order to be an effective disinfectant. Find out how to kill viruses here.

    To mix your own DIY homemade hand sanitizer because of the hand sanitizer shortage, use the popular germ-busting 'Make your own hand sanitizer' recipes explained here. You can fight COVID-19, by using a homemade hand sanitizer recipe that calls for 1 cup of 91% isopropyl alcohol and ½ cup of aloe vera gel in the recipe

    You can mix (2:1 proportion) 91% or 99% isopropyl alcohol and a stabilizer like natural aloe vera gel to make an effective antiviral handrub to protect your hands. You can buy ingredients like ethanol (commonly available at 90%-95%) at LabAlley.com because they are hard to find at stores like Walgreens or Target. Get a good recipe for hand sanitizer using hydrogen peroxide here.

    The WHO's official instructions for a recipe for hand sanitizer using glycerin calls for denatured alcohol or isopropyl alcohol, glycerol (also known as glycerin), hydrogen peroxide and sterile water. Typical ingredients for sale at LabAlley.com that are listed in safe recipes for hand sanitizers and antiseptic topical solutions include ethanol (alcohol), isopropyl alcohol (IPA), hydrogen peroxide (H2O2), glycerol and high purity water.

    Safe recipes for DIY homemade hand sanitizers and handrubs include the following raw materials and various ingredients in their formulation and compounding instructions.

    Shop Online For The Best Rated Coronavirus Disinfectants And Virus Killers To Prevent The Spread Of Infectious Diseases At LabAlley.com
    04/06/20

    List N: Products With Emerging Viral Pathogens And Human Coronavirus Claims For Use Against SARS-CoV-2

    Raw Materials For DIY Homemade Hand Sanitizers For Sale Online At LabAlley.com

    Antiviral disinfection products, ingredients for topical solutions and hand sanitizers and antiviral chemical compounds are for sale at LabAlley.com.

    How To Make Antiviral Hand Sanitizers, Cleaning Products And Disinfectants

    Buy Ingredients Recipes For Hand Sanitizers In Bulk Online Here Or By Phone: 512-668-9918

    If you have questions about ordering ingredients in bulk for recipes for hand sanitizers online here at LabAlley.com or would like to place an order, call 512-668-9918 or email customerservice@laballey.com to talk with an Hand Sanitizer Specialist. Use this 10% discount code to buy hand sanitizer ingredients online or by phone in the U.S: LAB10OFF.  

    Get information from Google to help your small business manage through the uncertainty caused by COVID-19 here. Buy antiviral hospital grade disinfectants, hand sanitizers, sterilization sprays, cleaners and detergents here. Buy antiviral hand sanitizer ingredients, antiviral disinfectants, antiviral products And antiviral chemical compounds at wholesale prices here. Buy supplies and chemical ingredients to make coronavirus disinfection products hereViruses can be eliminated with soap, bleach, alcohol, food or UV light.

     

    Recipe For Hand Sanitizer Using Essential Oils | Ingredients 

    • 2 tablespoons rubbing alcohol at least 70%
    • 1 tablespoon aloe vera gel
    • 2 teaspoons vegetable glycerin
    • 4 drops Tea Tree Essential Oil
    • 3 drops Lemon Essential Oil
    • 3 drops Lavender Essential Oil
    • 2 oz flip-top container  

    How Do You Make Your Own Hand Sanitizer?

    Dr. Rishi Desai, chief medical officer of Osmosis, and a former epidemic intelligence service officer in the division of viral diseases at the CDC, says that the hand sanitizer recipe below will kill 99.9 percent of germs after 60 seconds.

    Hand Sanitizer Recipe | What You’ll Need:

    Directions: 

    • Pour all ingredients into a bowl, ideally one with a pouring spout like a glass measuring container.
    • Mix with a spoon and then beat with a whisk to turn the sanitizer into a gel.
    • Pour the ingredients into an empty bottle for easy use, and label it “hand sanitizer.”

    Jagdish Khubchandani, PhD, associate professor of health science at Ball State University, shared a similar formula.

    His hand sanitizer formula combines: 

    If you are making hand sanitizer at home, Khubchandani says to adhere to these tips:

    • Make the hand sanitizer in a clean space. Wipe down counter tops with a diluted bleach solution beforehand.
    • Wash your hands thoroughly before making the hand sanitizer.
    • To mix, use a clean spoon and whisk. Wash these items thoroughly before using them.
    • Make sure the alcohol used for the hand sanitizer is not diluted.
    • Mix all the ingredients thoroughly until they are well blended.
    • Do not touch the mixture with your hands until it is ready for use.

    For a larger batch of hand sanitizer, the World Health Organization (WHO) has a formula for a hand sanitizer that uses:

    Is It Safe?

    DIY hand sanitizer recipes are all over the internet these days — but are they safe?

    These recipes, including the ones above, are intended for use by professionals with both the expertise and resources to safely make homemade hand sanitizers. Homemade hand sanitizer is only recommended in extreme situations when you’re unable to wash your hands for the foreseeable future.

    Improper ingredients or proportions can lead to:

    • lack of efficacy, meaning that the sanitizer may not effectively eliminate risk of exposure to some or all microbes
    • skin irritation, injury, or burns
    • exposure to hazardous chemicals via inhalation 

    Homemade hand sanitizer is also not recommended for use with children. Children may be more prone to improper hand sanitizer usage, which could lead to greater risk for injury.

    What Germs Can Hand Sanitizer Kill? 

    According to the CDCTrusted Source, an alcohol-based hand sanitizer that meets the alcohol volume requirement can quickly reduce the number of microbes on your hands. It can also help destroy a wide range of disease-causing agents or pathogens on your hands, including the novel coronavirus SARS-CoV-2.

    However, even the best alcohol-based hand sanitizers have limitations and do not eliminate all types of germs.

    According to the CDC, hand sanitizers won’t get rid of potentially harmful chemicals. It’s also not effective at killing the following germs: 

    Also, a hand sanitizer may not work well if your hands are visibly dirty or greasy. This may happen after working with food, doing yard work, gardening, or playing a sport.

    If your hands look dirty or slimy, opt for handwashing instead of a hand sanitizer. 

    Protection For U.S. Consumers From Fraudulent Coronavirus Disinfectant Claims
    Posted on April 4, 2020 

    U.S. Environmental Protection Agency (EPA) Administrator Andrew Wheeler hosted an interactive telephone call with U.S. retailers and third-party marketplace platforms to discuss imposter disinfectant products and those that falsely claim to be effective against the novel coronavirus, SARS-CoV-2, the cause of COVID-19. The E.P.A. has threatened legal proceedings against vendors of bogus coronavirus (COVID-19) cleaners, disinfectants and sanitizers. While such products might not be harmful, they offer the public a dangerously false sense of protection that could deter social distancing and promote the spread of COVID-19. The federal government is asking online retailers to take unregistered products that falsely claim protection from coronavirus off the market. The EPA has continued to add new surface disinfectant products to List N in an effort to combat COVID-19. Any brand that claims to kill or repel bacteria or viruses should be tested and registered by the E.P.A. and with the federal government. 

    Buy Safe Ingredients And Chemicals For DIY Homemade Hand Sanitizers, Cosmetics, Makeup, Lotions, Soaps, Household Cleaning Products, Laboratory Sterilization, Food And Beverage Processing, Skin Care Formulations, Hospital Disinfectants, Personal Care Products, Botanical And Essential Oils, Botanical Extracts, Pharmaceutical Drugs, Herbal Tinctures, Kid Safe Pools, Pest Control Products, Lawn Care Products, Chemistry Labs, Natural Health Supplements And Vitamins, Coronavirus Disinfection Products, Perfumes, Hospital Grade Detergents, Disinfecting Wipes And Disinfectant Sprays At LabAlley.com

    Buy bulk natural ingredients and antiviral chemicals, bulk food grade chemicals and organic raw materials for safe recipes for DIY homemade hand sanitizers here. Buy antiviral hand sanitizer ingredients, antiviral disinfectants, antiviral products and antiviral chemical compounds here. Buy antiviral hospital grade disinfectants, pharmaceutical grade substances, hand sanitizers, sterilization sprays, wipes, cleaners and detergents here

    Buy lab supplies, laboratory glassware, chemical crystals and powders, oils, gels, spray bottles and stock chemical solutions to make Coronavirus disinfectants here. You can also buy other compounds and additives for safe hand sanitizer recipes, cosmetics and personal care products at LabAlley.com. Find out how chemicals are made, sold, priced, bought, shipped and used in the United States here.

    Popular additives for skin care products purchased online in bulk at wholesale prices at LabAlley.com include food grade ethanol, 100% alcohol, 95% alcohol, 70% alcohol, 99% isopropyl alcohol, 91% isopropyl alcohol, 70% isopropyl alcohol, 3% hydrogen peroxide, 6% hydrogen peroxidefood grade hydrogen peroxide, food grade (FCC) vegetable glycerin, Food Grade (FCC) glycerol, solvents, aqueous acids and acids in crystalline powder form.

    Shop for popular ingredients used to formulate DIY homemade personal care products such as high purity water, citric acid, menthol crystalsnatural peppermint oil, Polysorbate 80, phenol, trichloroacetic acid  (TCC), denatured alcoholn-Propanol, MCT (Coconut Oil), sodium hypochloritesalicylic acid, fumaric acidsodium hydroxide, triethanolaminebenzalkonium chloridetriethylene glycolpropylene glycol, ammonium hydroxide, olive oil at LabAlley.com. Buy antiviral hand sanitizer ingredients, antiviral disinfectants, antiviral products and antiviral chemical compounds here. Buy antiviral hospital grade disinfectants, pharmaceutical grade substances, hand sanitizers, sterilization sprays, wipes, cleaners and detergents here. Buy lab supplies, chemical powders, oils, gels, spray bottles and chemical solutions to make Coronavirus disinfectants here at LabAlley.com.

     

    Cleaning And Disinfection Of Sterile Processing Facilities | Hand Sanitizers 

    Hand sanitizers fall into two groups: alcohol-based, which are more common; and non-alcohol-based. The most commonly used alcohol-based hand sanitizers are isopropyl alcohol or a form of denatured ethanol (i.e. industrial methylated spirits), normally at a 70% concentration. Sanitizers are applied to either bare skin (on entering a cleanroom) or to gloved hands (within the cleanroom). Read more here.

     

    Hand Sanitizer Recipes Are Listed Below

    Compounding Alcohol-Based Hand Sanitizer During COVID-19 Pandemic
    March 24, 2020

    This document is for informational purposes only and is intended to address shortages of alcohol-based hand sanitizers associated with the COVID-19 pandemic. This does not reflect the Compounding Expert Committee’s opinions on future development or revisions to official text of the USP-NF. USP is actively monitoring the evolving situation and will update this document accordingly. 

    Background and Introduction 

    In light of the rapidly evolving COVID-19 pandemic, there is an expected shortage of alcohol-based hand sanitizers. The Centers for Disease Control (CDC) recommends washing hands with soap and water whenever possible because handwashing reduces the amounts of all types of germs and chemicals on hands. If soap and water are not available, using a hand sanitizer with a final
    concentration of at least 60% alcohol can help you avoid getting sick and spreading germs to others. Noting that consumers are experiencing difficulties in accessing alcohol-based hand sanitizers containing at least 60% alcohol, on March 14, 2020, FDA released an Immediately in Effect Guidance titled, “Policy for Temporary Compounding of Certain Alcohol-Based Hand Sanitizer
    Products During the Public Health Emergency.” During this pandemic, USP supports State Boards and other regulators using risk-based enforcement discretion related to the compounding of alcohol-based hand sanitizers for consumer use. 

    The USP Compounding Expert Committee (CMP EC) provides the following recommendations for compounding alcohol-based hand sanitizers for use during shortages associated with the COVID-19 pandemic. In light of the public health emergency posed by COVID-19, this document was developed without a public comment period. This document is not a USP compendial standard; rather, it reflects considerations developed by the USP CMP EC, based on their scientific and professional expertise, and with input from regulatory agencies at the federal and state level. If implementing the provisions in this document, the expectation is that compounders follow USP General Chapter <795>
    Pharmaceutical Compounding – Nonsterile Preparations, including the following:

    • Personnel trained in the compounding procedures
    • USP, NF or Food Chemicals Codex (FCC) grade ingredients as the recommended source of ingredients | When components meeting compendial quality standards are not obtainable, components of equivalent quality – such as those that are chemically pure, analytical reagent grade or American Chemical Society-certified – may be used.
    • All equipment to be clean, properly maintained, and used appropriately
    • A Master Formulation Record and Compounding Record to be prepared
    • A Beyond-Use Date to be assigned
    • The preparation to be appropriately labeled | Label to note the final concentration of ethanol or isopropyl alcohol 

    The following are three formulations for compounding alcohol-based hand sanitizers. Formulation 1 and 2 were developed based on WHO recommendations.

    Formulation 1: Ethanol Antiseptic 80% Topical Solution

    Prepare Ethanol Antiseptic Topical Solution containing ethanol 80% (v/v) as follows (see Pharmaceutical Compounding—
    Nonsterile Preparations <795>).

    • Ethanol 96% 8333 mL
    • Hydrogen Peroxide 3% 417 mL
    • Glycerol 98% 145 mL
    • Water, a sufficient quantity to make 10000 mL | Water may be distilled water, cold boiled potable water, reverse osmosis water, or filtered water

    Measure the quantities of Ethanol, Hydrogen Peroxide, and Glycerol in suitable containers. Transfer the Ethanol and Hydrogen Peroxide into a suitable calibrated container and mix gently. Transfer the Glycerol stepwise and quantitatively into the calibrated container and mix gently after each addition. Rinse the container containing glycerol several times with water and add the contents to the calibrated container. Add sufficient Water to bring to final volume. Mix well. Transfer the solution into suitable containers.

    • Packaging and Storage: Package in suitable containers and store at controlled room temperature.
    • Labeling: Label to state for external use only, the percentage of ethanol, and the Beyond-Use Date.
    • Beyond-Use Date: NMT 30 days after the date on which it was compounded, when stored at controlled room temperature. 

    Formulation 2: Isopropyl Alcohol Antiseptic 75% Topical Solution

    Prepare Isopropyl Alcohol Antiseptic Topical Solution containing isopropyl alcohol 75% (v/v) as follows (see Pharmaceutical Compounding—Nonsterile Preparations <795>)

    Measure the quantities of Isopropyl Alcohol, Hydrogen Peroxide, and Glycerol in suitable containers. Transfer the Isopropyl Alcohol and Hydrogen Peroxide into a suitable calibrated container and mix gently. Transfer the Glycerol stepwise and quantitatively into the calibrated container. Mix gently after each addition. Rinse the container containing glycerol several times with Water and add the contents to the calibrated container. Add sufficient Water to bring to final volume. Mix well. Transfer the solution into suitable containers.

    • Packaging and Storage: Package in suitable containers and store at controlled room temperature.
    • Labeling: Label to state for external use only, the percentage of isopropyl alcohol, and the Beyond-Use Date.
    • Beyond-Use Date: NMT 30 days after the date on which it was compounded, when stored at controlled room temperature.

    Formulation 3: Isopropyl Alcohol Antiseptic 60% Topical Solution

    Prepare Isopropyl Alcohol Antiseptic Topical Solution containing isopropyl alcohol 60% (v/v) as follows (see Pharmaceutical Compounding—Nonsterile Preparations <795>).

    Measure the quantities of Isopropyl Alcohol, Hydrogen Peroxide, and Glycerol in suitable containers. Transfer the Isopropyl Alcohol and Hydrogen Peroxide into a suitable calibrated container and mix gently. Transfer the Glycerol stepwise and quantitatively into the calibrated container. Mix gently after each addition. Rinse the container containing glycerol several times with Water and add the contents to the calibrated container. Add sufficient Water to bring to final volume. Mix well. Transfer the solution into suitable containers.

    • Packaging and Storage: Package in suitable containers and store at controlled room temperature.
    • Labeling: Label to state for external use only, the percentage of isopropyl alcohol, and the Beyond-Use Date.
    • Beyond-Use Date: NMT 30 days after the date on which it was compounded, when stored at controlled room temperature.

    Antiviral treatment is recommended as early as possible for any patient with confirmed or suspected influenza who: 

    • is hospitalized;
    • has severe, complicated, or progressive illness; or
    • is at higher risk for influenza complications.

    Decisions about starting antiviral treatment should not wait for laboratory confirmation of influenza. For outpatients with acute uncomplicated influenza, oral oseltamivir, inhaled zanamivir, intravenous peramivir, or oral baloxavir may be used for treatment. For patients with severe or complicated illness with suspected or confirmed influenza (e.g., pneumonia, or exacerbation of underlying chronic medical condition) who are not hospitalized, antiviral treatment with oral or enterically-administered oseltamivir is recommended as soon as possible. Read more here.

    ADA Height For Hand Sanitizers And Soap Dispensers

    ADA Requirements for Soap Dispensers. The American Disabilities Act (ADA) was signed into law in 1990 and requires facilities to make accommodations for disabled people. Soap dispensers should not be placed higher than 44 inches if the reach depth (counter) is more than 20 inches but not more than 25 inches in depth. Read more here

    Glycerol Inactivates Viruses

    Effect of glycerol on intracellular virus survival: implications for the clinical use of glycerol-preserved cadaver skin. 

    Glycerol has long been used for the preservation of skin allografts. The antimicrobial activity of glycerol has not been fully documented. This paper reports the results of an investigation of a model studying the effect of glycerol on the inactivation of intracellular viruses. Two viruses--herpes simplex type I (HSV-1) and poliovirus--were cultured within human dermal fibroblasts. These intracellular viruses were incubated with 50 per cent, 85 per cent and 98 per cent glycerol at 4 degrees C and 20 degrees C for 4 weeks. Each week, the cultures in glycerol and controls in fibroblast maintenance medium were assayed for virus infectivity by examining the ability of harvested viruses to infect further fibroblasts. At 4 degrees C, 85 per cent glycerol could not fully inactivate intracellular HSV-I or poliovirus even after 4 weeks; 98 per cent glycerol inactivated intracellular HSV-I (after 3 weeks) but could not fully inactivate intracellular poliovirus after 4 weeks. At 20 degrees C, 85 per cent glycerol inactivated intracellular HSV-I (within 1 week) but could not fully inactivate intracellular poliovirus after 4 weeks; 98 per cent glycerol inactivated intracellular HSV-I (within 1 week) and inactivated intracellular poliovirus (after 2 weeks). It is suggested that, on the basis of this study, glycerol can reduce intracellular virus infectivity but that its effects are very dependent on concentration, time and temperature such that we would recommend that allograft skin be exposed to 98 per cent glycerol for a minimum of at least 4 weeks at a minimum temperature of 20 degrees C before clinical use.

    Monolaurin, also known as glycerol monolaurate (GML), glyceryl laurate or 1-lauroyl-glycerol, is a monoglyceride. It is the mono-ester formed from glycerol and lauric acid. Monolaurin is known to inactivate lipid-coated viruses by binding to the lipid-protein envelope of the virus, thereby preventing it from attaching and entering host cells, making infection and replication impossible. Other studies show that Monolaurin disintegrates the protective viral envelope, killing the virus.Monolaurin has been studied to inactivate many pathogens including Herpes simplex virus and Chlamydia trachomatis. Read more here.

     

    U.S. Distilleries Buy Ethanol, Glycerin And Hydrogen Peroxide At LabAlley.com To Make Hand Sanitizers And Handrub Formulations

    March 23, 2020

    Sales of hand sanitizers in the U.S. are way up. These products are becoming scarce in the face of the growing COVID-19 outbreak. Download the World Health Organization's recipe for recommended handrub formulations here

    Distilleries in the U.S. purchase alcohol and ethanol at LabAlley.com to produce a 160-proof clear spirit to use as a hand sanitizer. Get a complete list of distilleries (Including Anheuser-Busch) making hand sanitizers instead of spirits here.  Anheuser-Busch and distilleries are racing to make hand sanitizers amid the Coronavirus pandemic.

    American distilleries are assisting their communities by producing their own hand sanitizer using a recipe from the World Health Organization. The recipe "starts with ethanol, which is what we have plenty of in the distillery, then you add glycerin, hydrogen peroxide water and you mix it up," Scott Jendrek, owner of Patapsco Distilling Co. in Sykesville, Maryland, told a local NBC News affiliate.

     

    Antiviral Products For Sale Online

    A virus is a small infectious agent that replicates only inside the living cells of an organism. Several new antiviral compounds and potent and selective antiviral agents against herpes virus infections have been developed. Viruses can infect all types of life forms, from animals and plants to microorganisms, including bacteria and archaea.

    Viruses are very tiny germs made of genetic material inside of a protein coating. Viral infections play a key role in human diseases. Quercetin, morin, rutin, taxifolin, dihydrofisetin, leucocyanidin, pelargonidin chloride, apigenin, catechin, hesperidin, and naringin have been reported to possess antiviral activity against some of 11 types of viruses.

    Because lots of viruses lack efficient antiviral therapies and preventive vaccines, antiviral compounds sold at LabAlley.com, such as Quinine Sulfate and Benzalkonium Chloride are used medicinally because of their antiviral effect

    Because viruses use vital metabolic pathways within host cells to replicate, they are difficult to eliminate without using drugs that cause toxic effects to host cells in general. The most effective medical approaches to viral diseases are vaccinations to provide immunity to infection, and antiviral drugs that selectively interfere with viral replication.

    Phenolic compounds are derived from the secondary plant metabolism, although they can also be obtained by synthetic processes. Many studies have shown a great range of pharmacological effects for these substances, including vasodilatation, antiallergenic, antiinflammatory and antiviral properties, among others.

    Antiviral drugs are used in the U.S. to treat viral infections rather than bacterial infections. Buy antiviral phenolic compounds at LabAlley.com for disinfection, food and medicinal uses here.

    Hospitals in the United States by hospital grade disinfectants and antiviral cleaning chemicals such as hydrogen peroxide, isopropyl alcohol, 100% alcohol, 95% alcohol and 70% alcohol at LabAlley.com. American consumers, businesses and healthcare facilities buy supplies and chemical ingredients to manufacture Coronavirus infection protection products here.

    U.S. firms buy chemical substances and antiviral substances online at LabAlley.com to manufacture antiviral agents which inhibit production of viruses that cause disease. Food manufacturing facilities order hydrochloric acid and ascorbic acid to kill viruses. Acidic ozone water made with hydrochloric acid can deactivate H1N1 viruses very effectively. Agricultural and botanical businesses in the U.S. buy chemical supplies from LabAlley.com to make medicinal oils and tinctures that kill viruses. Home-based cosmetic manufacturers order antiviral substances such as trichloroacetic acid to make skin care products and personal care products.

    A number of different organic acids sold online at LabAlley.com produce residual antirhinoviral activity. Salicylic acid, fumaric acid, and benzoic acid produced at least a 2-log reduction in viral titersHydrogen peroxide sold online at LabAlley.com is antiviral, antibacterial and anti-fungal. Hospitals frequently order this product for virus inactivation processes. H2O2 is a convenient means for virus inactivation.

     

    Types Of Antiviral Products Sold Online At LabAlley.com

     

    About EPA Approved Disinfectants

     

    Coronavirus (COVID-19) Update: FDA Provides Guidance On Production Of Alcohol-Based Hand Sanitizer To Help Boost Supply, Protect Public Health
    March 20, 2020

    As part of the U.S. Food and Drug Administration’s ongoing commitment to address the coronavirus (COVID-19) pandemic, the agency has issued two guidance documents to communicate its policy for the temporary manufacture of certain alcohol-based hand sanitizer products. These guidance documents will be in effect for the duration of the public health emergency declared by the Secretary of Health and Human Services (HHS) on January 31, 2020.

    “We are aware of significant supply disruptions for alcohol-based hand sanitizers. Many manufacturers make hand sanitizers, and several have indicated that they are working to increase supply,” said FDA Commissioner Stephen M. Hahn, M.D. “In the meantime, these guidances provide flexibility to help meet demand during this outbreak. We will continue to work with manufacturers, compounders, state boards of pharmacy and the public to increase the supply of alcohol-based hand sanitizer available to Americans.”

    Because of an increased demand for alcohol-based hand sanitizers during the COVID-19 pandemic, there have been reports of some consumers attempting to make hand sanitizers for personal use. The agency lacks information on the methods being used to prepare such products and whether they are safe for use on human skin.

    The guidance Temporary Policy for Preparation of Certain Alcohol-Based Hand Sanitizer Products During the Public Health Emergency (COVID-19), is immediately in effect and outlines that the agency does not intend to take action against manufacturing firms that prepare alcohol-based hand sanitizers for consumer use and for use as health care personnel hand rubs during this ongoing public health emergency as described in the guidance .

    The second guidance, Policy for Temporary Compounding of Certain Alcohol-Based Hand Sanitizer Products During the Public Health Emergency, is in effect for the temporary compounding of certain alcohol-based hand sanitizers by pharmacists in state-licensed pharmacies or federal facilities and registered outsourcing facilities. Compounding is generally a practice in which a licensed pharmacist, a licensed physician, or, in the case of an outsourcing facility, a person under the supervision of a licensed pharmacist, combines, mixes, or alters ingredients of a drug to create a tailor-made medication. The temporary policy outlined by the agency does not require compounders to obtain a patient-specific prescription.

    The FDA’s guidance documents apply only to handrub products prepared using the United States Pharmacopoeia or Food Chemical Codex grade ingredients specifically described in the guidance, consistent with World Health Organization recommendations. The guidance documents also discuss product labeling and certain manufacturing methods and reporting requirements, such as that manufacturers must have a way to accept and submit adverse event reports to FDA for any products they manufacture.

    The agency realizes that manufacturers and compounders will need time to ramp up production as they obtain the ingredients needed to make these hand sanitizers. During this time the FDA will work to assist them as they develop hand sanitizers to make available for the American public.

    The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation's food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.

     

    Buy Chemical Compounds, Excipients, Powders And Pharmaceutical Manufacturing Substances From LabAlley.com To Develop And Produce Antiviral Drugs (Antiviral Agents) 

     

    Most of the antiviral drugs and antiviral agents now available are designed to help deal with HIV, herpes viruses, the hepatitis B and C viruses, and influenza A and B viruses. Researchers are working to extend the range of antivirals to other families of pathogens. Antibiotic drugs are often classified by their spectrum of activity. These classifications include antibacterial medications, antifungal drugs, antimycobacterial drugs, antiparasitic/antiprotozoal/anthelminthic drugs and antiviral formulations. LabAlley sells chemicals and supplies used to manufacture antiviral medications. 

    Viruses consist of a genome and sometimes a few enzymes stored in a capsule made of protein (called a capsid), and sometimes covered with a lipid layer (sometimes called an 'envelope'). Viruses cannot reproduce on their own, and instead propagate by subjugating a host cell to produce copies of themselves, thus producing the next generation. Researchers working on such "rational drug design" strategies for developing antivirals have tried to attack viruses at every stage of their life cycles

    Antiviral drugs are a class of medication used specifically for treating viral infections rather than bacterial ones. Most antivirals are used for specific viral infections, while a broad-spectrum antiviral is effective against a wide range of viruses. Unlike most antibiotics, antiviral drugs do not destroy their target pathogen; instead they inhibit their development.

    Viruses represent a large group of infective agents that are composed of a core of nucleic acids, either RNA or DNA, surrounded by a layer of protein. They are not really living organisms according to general understanding, since they lack the cell membrane that is associated with living cells. Viruses can reproduce only inside a living cell, and they cause many diseases. Viruses are not normally affected by antibiotics but a small number of viruses can either be destroyed or have their growth stopped by antiviral drugs.

    Lab Alley sells lab equipment, chemical compounds, reagents, scientific instruments and laboratory supplies to drug manufacturing companies and pharmaceutical firms. Lab Alley customers synthesize antiviral drugs and produce pharmaceutical formulations through various processes which include milling, powder blending, granulation, coating, hot metal extrusion, tablet pressing and others. Pharmaceutical formulation, in pharmaceutics, is the process in which different chemical substances, including the active drug, are combined to produce a final medicinal product. The word formulation is often used in a way that includes dosage form.

    Common chemicals purchased online at LabAlley.com by antiviral drug manufacturers include solvents used for extraction. Lab Alley also sells excipients and chemicals in powder form that are used in the pharmaceutical industry. Common excipients purchased online at LabAlley.com by pharmaceutical manufacturing enterprises include starch, cellulose, alginates, silicon, silica compounds, stearic acid and magnesium stearate. Antiviral drug manufacturing operations and pharmaceutical companies in the U.S. purchase chemicals in a powdered, crystal, flake or crystalline form online at LabAlley.com.

     

    Antiviral Wipes, Sprays And Soaps

    Clorox wipes kill bacteria and viruses, and I don't have to wash after using them. Quote: Clorox Disinfecting Wipes kill 99.9% of viruses and bacteria, including cold and flu, E. Coli, Salmonella, Staph, and Strep. Read more here. Buy Conzerol Antiviral Molluscum Treatment Soap, here. Anti-viral disinfectant sprays help to stop the spread of bacterial and viral diseases such as PMV and Newcastle Disease.

     

    Is Ethanol A Disinfectant?

    Ethanol (ethyl alcohol, C2H5OH) and 2-propanol (isopropyl alcohol, (CH3)2CHOH) have similar disinfectant properties. They are active against vegetative bacteria, fungi, and lipid-containing viruses but not against spores. Their action on non-lipid-containing viruses is variable. Read more here. Learn about the viral activity of 70% ethanol vs enveloped and non-enveloped viruses, here.

     

    Isopropyl Alcohol vs Ethanol

    These two alcohols are the same actually when it comes to disinfectant properties. However, they have slight differences when it rubbed on the skin. Ethanol is the type of alcohol present in alcoholic beverages. Isopropyl alcohol is also known as isopropanol, 2-propanol or rubbing alcohol. Read more here.

     

    Antiviral Activity Of Alcohol For Surface Disinfection

    Bacteria and viruses from the patient's mouth travel with dental splatter and spills. A surface disinfectant should possess antiviral activity as well as antibacterial action. Because of frequent and 'open' application in the dental office, such a disinfectant should be non-toxic, non-allergenic and safe for the hygienist. It now appears that high-concentration alcohol mixtures (i.e. 80% ethanol + 5% isopropanol) are not only excellent antibacterials, but quickly inactivate HIV as well as hepatitis B and hepatitis C viruses. Compared to alternative surface disinfectants, use of high-concentration alcohol for the spray-wipe-spray method of surface disinfection in dentistry appears safe and efficient. However, dried matter should be wiped and hydrated first. Read more here.

     

    Use Benzalkonium Chloride To Inactivate Viruses

    Benzalkonium chloride (as Roccal or Zephiran) was found to inactivate influenza, measles, canine distemper, rabies, fowl laryngotracheitis, vaccinia, Semliki Forest, feline pneumonitis, meningopneumonitis, and herpes simplex viruses after 10 minutes of exposure at 30 C or at room temperature. Read more here

    Type A influenza viIrus was inactivated by concentrations of benzalkoniunm chloride as low as 0.025 mng/iml. Measles and canine distemper viruses were also sensitive to the quaternary. Feline pneuiinonitis and miieningopneumionitis agents were inactivated by benzalkonium chloride after 10 minutes of exposure at room temperature. Rabies, fowl laryngotracheitis, Seliliki Forest, and herpes simplex viruses were rapidly inactivated by low concentrations of benzalkonium chloride. Review more information on the virucidal activity of benzalkonium chloride for 13 viruses here.

     

    Benzalkonium Chloride Disinfectant

    Benzalkonium chloride is widely used as a preservative in eyedrops; in higher concentrations it is used as an antiseptic and disinfectant. Read more here.

     

    Antiviral Phenolic Compounds And Phenolic Household Disinfectant Ingredients For Sale Online At LabAlley.com

     

    Phenolics are active ingredients in some household disinfectants. Phenolic compounds, have been studied extensively (biologically and chemically) due to their extensive antiviral activities. Learn about the cytotoxic, antiviral properties and anti-HSV-1 activities of phenolic compounds here. They are also found in some mouthwashes and in disinfectant soap and handwashes. Phenol is probably the oldest known disinfectant as it was first used by Joseph Lister (pioneer of antiseptic surgery), when it was called carbolic acid.

    Phenol is also called carbolic acid, hydroxybenzene, oxybenzene, phenylic acid. a white, crystalline, water-soluble, poisonous mass, C6H5OH, obtained from coal tar, or a hydroxyl derivative of benzene: used chiefly as a disinfectant, as an antiseptic, and in organic synthesis.

    Phenols are widely used in household products and as intermediates for industrial synthesis. For example, phenol itself is used (in low concentrations) as a disinfectant in household cleaners and in mouthwash. Phenol may have been the first surgical antiseptic. Read more here.

    Phenol is an aromatic organic compound with the molecular formula C6H5OH. It is a white crystalline solid that is volatile. The molecule consists of a phenyl group (−C6H5) bonded to a hydroxy group (−OH). Mildly acidic, it requires careful handling because it can cause chemical burns. Read more here.

     

    Buy Antiviral Phenolic Compounds Online At LabAlley.com

    Phenolics are active ingredients in some household disinfectants. They are also found in some mouthwashes and in disinfectant soap and hand washes. Phenol (carbolic acid) is one of the oldest antiseptic agents. Phenol has good penetrating power into organic matter and is mainly used for disinfection of equipment or organic materials that are to be destroyed (eg, infected food and excreta).

     

    Why You Shouldn't Make Your Own Hand Sanitizer
    Written By Sarah Mitroff | Published On March 24, 2020 By CNET

    It's easy to mess up making DIY hand sanitizer, so do this instead.

    The rapid spread of coronavirus (or COVID-19) has people clearing out shelves of hand sanitizer across the US. And if you try to buy it online, good luck -- most of it is out of stock or marked up on Amazon, Walmart.com, Bath and Body Works, Walgreens and other retailers. Target and regional grocery store Kroger now have limits on how many "anti-viral" products you can purchase at a time. And, New York Governor Andrew Cuomo announced that New York state will be producing its own hand sanitizer to address the shortages and price gouging.

    The shortages and buying limits have spurred people to make their own hand sanitizer using recipes from Twitter, Reddit, Pinterest, countless blogs and even a pharmacy. But just because these recipes exist doesn't mean you should follow them.

    Recipe For Hand Sanitizer On YouTube 

    What you'll need: 

    • 91% Isopropyl alcohol (rubbing alcohol)
    • Aloe vera gel
    • Mixing bowl
    • Spoon or something for whisking
    • Small container, such as a 3 oz. travel bottle
    • Optional: essential oil to give the liquid a fragrance

    Directions: 

    • In a mixing bowl, stir Isopropyl alcohol and aloe vera gel together until well blended.
    • Add 8-10 drops of scented essential oil (optional, but nice!). Stir to incorporate.
    • Pour the homemade hand sanitizer into an empty container and seal. Write “hand sanitizer” on a piece of masking tape and affix to the bottle.


    Reasons To Not Make Your Own Hand Sanitizer

    First, the Centers of Disease Control recommends washing your hands over using hand sanitizer, unless you don't have access to soap and water. Second, the FDA has said that it knows people are making DIY hand sanitizer at home, but that it doesn't have any "verifiable information on the methods being used to prepare such products and whether they are safe for use on human skin."

    Lastly, experts caution that making homemade hand sanitizer is harder than it seems. If you don't get the concentration right, experts warn that you'll end up with something that isn't effective or is too harsh, and is a waste of ingredients.

    The key is to get the right ratio of ingredients. The CDC Control recommends using a hand sanitizer that contains at least 60% alcohol, which store-bought hand sanitizers have. But trying to replicate that on your own can be tricky, Dr. Sally Bloomfield, with the London School of Hygiene and Tropical Medicine told the Guardian.

    In the video below, Dr. Jason Kindrachuk, an assistant professor of Viral Pathogenesis at the University of Manitoba explains that you're better off using soap than trying to make your own hand sanitizer.

     


    Official Hand Sanitizer Formulas 

    Both the World Health Organization and the FDA have guidelines for making hand rubs (the agencies' term for hand sanitizer), but they are designed for medical professionals, not the average consumer. The WHO's official instructions call for denatured alcohol or isopropyl alcohol, glycerol (also known as glycerin), hydrogen peroxide and sterile water. You must measure the concentration of alcohol in the final product using an alcoholometer to ensure it is effective at killing germs and safe to use.

    The recipe also does not recommend including any dyes, essential oils or other fragrances because they could cause an allergic response -- a lot of DIY recipes call for essential oils to mask the smell of alcohol.

    On March 20, 2020, the FDA released its temporary guidelines for pharmacists and other manufacturers to make hand sanitizer. Under its recommendation, you must use pharmacy-grade ingredients, test the alcohol level in the final product, and label the finished formula. The FDA recommends the WHO's formula, and echoes that adding additional active or inactive ingredients (such as aloe vera gel or essential oils) "may impact the quality and potency of the product."

    The FDA also notes that it is "aware of reports that some consumers are producing hand sanitizers for personal use; the Agency lacks information on the methods being used to prepare such products and whether they are safe for use on human skin." Unless you can follow the instructions outline by the WHO, making your own hand sanitizer just isn't smart for your own safety.

    Homemade Hand Sanitizer Recipes 

    Most of the countless recipes out there use a mix of 91% or 99% isopropyl alcohol (also known as rubbing alcohol) and aloe vera gel, which is necessary to add moisture to your skin because alcohol will dry it out. In these recipes, the typical ratio is two thirds rubbing alcohol to one third of a cup of aloe vera gel.

    Even if you follow that recipe, you can still mess it up. Mixing it at home, you can't control how the alcohol gets diluted in the final product. If you don't use enough aloe gel, it will dry out the skin on your hands, which can cause it to crack or bleed (the same is true if you just pour rubbing alcohol on your skin).

    But if you don't use enough alcohol, the final product won't be as effective at killing germs as store-bought hand sanitizer -- rendering it basically useless according to some experts. You can also contaminate your batch with bacteria by not using clean tools to mix it together.

    The final issue is that because of the popularity of these homemade hand sanitizers, the ingredients are now harder to come by. So even if you want to make it, you might not be able to find rubbing alcohol and aloe vera at your local drugstore.

    You should avoid recipes that call for vodka or spirits because you need a high proof liquor to get the right concentration of alcohol by volume. That's because most liquor is mixed with water, so if you mix a 80-proof vodka (which is the standard proof) with aloe, you'll have hand sanitizer that contains less than 40% alcohol. In response to a tweet about someone using Tito's Vodka to make DIY hand sanitizer, the company responded by saying that you shouldn't use its product for that purpose.

     



    So What Should You Do Instead? 

    Wash your hands. The CDC and WHO both agree that's the best thing you can do right now to protect yourself from getting sick, either from coronavirus or anything else. Wash your hands with soap and water for 20 seconds, many times per day -- after you use the restroom, before and after you eat, before and after you prepare food and in many other scenarios.

    Also avoid touching your face in general, but especially with dirty hands. Most everything you touch throughout the day is covered in germs and if you touch your mucous membranes (lips, noise, eyes) you can spread viruses and bacteria into your own body.

    If you want to use other disinfecting products to clean your hands or surfaces, the Environmental Protection Agency released a full list of products that can kill the virus.

    I don't advise it, but if you're determined to make your own hand sanitizer (and can actually find the ingredients to do so), avoid any recipes that don't use at least 60% alcohol. Otherwise, just wash your damn hands.

    Whiskey Producers Are Making Hand Sanitizer. Here's How They Organized.
    Written By Maggie Kimberl | Published By Entrepreneur Media, Inc. On March 24, 2020

    With loosened laws and a lot of experimentation, the industry has stepped up to fill a critical need.

    The world needs hand sanitizer — far more than the existing hand sanitizer industry can produce. So the American whiskey industry, along with other alcohol industries like craft breweries, have begun stepping up. They’re hitting pause on making beverages, and have begun making the alcohol-based sanitizers that save lives.

    It’s an important example of how entrepreneurs can pivot and contribute to the fight against Covid-19. And it contains important lessons for other entrepreneurs on how to do the same.

    Lift Regulations

    In a way, the American whiskey industry was already primed for this work. Back in 1941, after the attack on Pearl Harbor, the American government assumed control of the distilling industry and converted many of the stills to produce high-proof ethanol. This ethanol was used for antifreeze, munitions, octane boosters, lacquer, synthetic rubber and more.

    Today, no government mandate was required — but government help was. When the COVID-19 crisis first hit, some of the smaller distilleries began trying to share their alcohol; any whiskey manufacturer will have parts of the distillate that can’t be used in beverages but could become a general-purpose cleaner. However, laws stood in their way. Strict regulations control what can and can’t happen in a distillery, and these businesses are heavily taxed. With these laws in place, the distilleries couldn’t be helpful.

    The industry started raising its voice, and policy-makers responded. Local, state and even federal laws were lifted or altered. On March 18, the Alcohol and Tobacco Tax and Trade Bureau, which oversees the industry, also cleared a path: It waived parts of a law, including requirements that distilleries obtain permits or bonds to produce hand sanitizer. Now distilleries could finally get to work.

    Create Many Different Solutions 

    Each distillery has taken a somewhat different path. Some distilleries chose to make sanitizing products, and then provide them for free to first responders and critical facilities and businesses. Others have chosen to sell their sanitizing products to the public, as a way to keep their staffs paid.

    In Kentucky, the response from the bourbon industry has been swift and decisive. Brown-Forman, one of the largest American-owned spirits manufacturers, started delivering free sanitizer to first responders in Woodford County, the location of its Woodford Reserve distillery. (Its Old Forester Distillery in Louisville, Kentucky will follow suit.) The Neeley Family Distillery is making small batches of hand sanitizer and allowing people to bring their own bottles to fill up for a donation to cover the costs. Lexington Brewing & Distilling, Rabbit Hole Distillery and Wilderness Trail Distillery have all announced efforts to produce hand sanitizer as well.

    Outside of Kentucky, many small distilleries are doing the same — including Smooth Ambler in West Virginia, Koval Distillery in Chicago, Corsair Distillery in Tennessee, American Craft Whiskey Distillery in California and Whisky Acres Distilling in Illinois. 

    Share Information Among Competitors

    But there’s a problem: Just because a distiller can make whiskey, that doesn’t mean they know how to make alcohol for hand sanitizer. To make it work, the industry has come together to share information — producing webinars, online guides, and more. Distilleries are modifying their equipment and learning on the fly.

    At Catoctin Creek Distillery in Virginia, Distiller Becky Harris says she’s working closely with the American Craft Spirits Association (ASCA), with daily meetings to devise the best possible course of action for distillers wanting to produce hand sanitizer. At one point, her husband and business partner, Scott Harris, was receiving 50 emails every hour from people asking about hand sanitizer. She says the media attention on this topic has been helpful, because it has shown regulatory bodies there is a huge surge in demand for these products, which in turn enabled the ASCA to streamline and expedite the process of building guidelines and finding supply in the supply chain.

    As the situation evolves, distilleries are also having to change their plans. In Michigan, for example, the Traverse City Whiskey Company originally wanted to sell hand sanitizer to the public — but then its inventory of 10,000 units sold out overnight. “The response and demand has been shocking,” says Chris Fredrickson, the company’s co-founder. “Because of this, we've evolved our strategy from retail to include medical and first responders, as that has been the greatest need.”

    What will come next? Nobody knows, of course — but more distilleries join the effort to produce hand sanitizer, and owners say they’ll look for even more ways to band together and support people in the industry. “I would say that whiskey drinkers are the most generous people on the planet,” says Bill Thomas, owner of the Jack Rose Dining Saloon in Washington D.C., who I spoke with recently for American Whiskey Magazine. “And this is absolutely proof that the whiskey drinker is the best kind of human being on the planet.”

    It’s also a lesson for other industries during this difficult time: With loosening regulations, you can collaborate with your peers on new innovations ... and start solving any problem you can.

    Recipe For Hand Sanitizer Using Witch Hazel | Ingredients

    • 2 ounce spray bottle
    • 5 drops vitamin E oil (optional, this makes for soft hands!)
    • 3 tablespoons witch hazel with aloe vera, vodka, or 190 proof grain alcohol (Everclear), see notes
    • 5 drops lemon essential oil
    • 5 drops orange essential oil
    • 5 drops tea tree essential oil. 

    Recipe For Hand Sanitizer With Vodka

    Why you shouldn’t use Tito’s Vodka to make hand sanitizer — or attempt to make your own hand sanitizer period. Hand sanitizer is selling out in stores over coronavirus fears, but doctors say you’re better off washing your hands. But some misinformed individuals have also been looking into making sanitizers with liquor, such as Everclear grain alcohol and Tito’s Handmade Vodka. Read more here

    Alcohol is the gold standard for anti-microbial action—there is a reason most store-bought hand sanitizers are alcohol-based. One option is to use vodka. Most vodka on store shelves is around 40-45% alcohol (80-90 proof), and then gets further diluted in this recipe. This is what we consider a “middle of the road” hand sanitizer. The vodka does make this version slightly drying to the hands.

    3M™ Disinfectant Concentrates and U.S. EPA Emerging Pathogen Policy

    Due to the 2019-nCoV being a newly emerging pathogen there is no U.S. EPA registered disinfectant currently available on the market with the 2019-nCoV efficacy claim specifically listed on their container label. The U.S. EPA Emerging Pathogen Policy allows for professional judgments on effectiveness of disinfectants with current registrations with similar, representative microorganism families based on their cell structures. A person with the appropriate knowledge and technical skills to analyze such information can make a determination based on published information on disinfectant cleaners that meet the U.S. EPA Emerging Pathogen Policy for use on non-critical, hard, non-porous surfaces as defined by U.S. EPA. The following products are U.S. EPA-registered 3M disinfectants that meet U.S. EPA’s Emerging Pathogen Policy.

    EPA Registered, Quaternary Disinfectant Cleaners | Kills HIV-1, Hepatitis B Virus (HBV), MRSA, VRE, KPC, Rotavirus, Acinetobacter, VRE, Herpes Simplex I And Other Pathogens

    EcoLab Virasept Surface Disinfectant Cleaner

    According to the company, Virasept is a patented ready-to-use, one-step detergent-disinfectant, virucide, bactericide, tuberculocide, fungicide, and sporicide that effectively cleans, disinfects, and deodorizes. It won't harm fixtures and is formulated for daily use. Buy it online at Walmart.com.

    US IPA Prices Soar On Rising Global Demand And Supply Shortage
    Author: Deniz Koray | Published By ICIS On March 19, 2020
    Posted Here On March 27, 2020

    HOUSTON (ICIS)--US isopropanol (IPA) prices surged this week on heavy demand for hand sanitizer during the coronavirus (Covid-19) crisis, and there are no quick fixes for either the strong demand or the shortages of product. While European prices had risen to even higher numbers in the past month, US increases had been modest. However, prices surged this week, as domestic IPA spot prices are now assessed at 62-85 cents/lb ($1,367-1,874/tonne) FOB (free on board) US Gulf. IPA prices DEL (delivered) to the US Gulf are assessed at 64-90 cents/lb. 

    DOMESTIC IPA MARKETS
    Until this week, prices in the US were increasing at much smaller rates than in Europe, generally in the range of 5 cents/lb or less. However, this week was a tipping point for the domestic market, as the US response to the coronavirus was heightened. Isopropyl alcohol is used in many hand sanitizers, which are in high demand among consumers because of their ability to kill germs. Hand sanitizers were among the first products to sell out at grocery stores and pharmacies, but demand has increased since then. It was believed that the US was not seeing the level of IPA price increases as in Europe since it had more ethanol. However, due to the increase in US exports to Europe as well as the rapid rise domestic demand, supply of IPA was nevertheless overwhelmed. One market participant said many producers were on sales allocations, but this could not be confirmed.

    EXPORT MARKETS
    Last week, an export deal for Europe was heard at $1,350/tonne (61.24 cents/lb) CFR (cost and freight) Europe. Another was heard at $1,700/tonne CFR Europe. This week, prices for individual deals were heard for up to triple these numbers in Europe on imported IPA. However, these are not yet considered representative for the market. According to a market source, prices of exports to Asia in the past several days doubled, while another market participant said that Latin American demand began to heavily increase this week, but that there was almost no supply to provide to buyers there. Export prices now range from 57.52-95.00 cents/lb, although much higher individual spot prices were heard. IPA is a solvent principally used in industrial and consumer products including cosmetics and personal-care products, paints and resins, pharmaceuticals, food, inks and adhesives. It is also used in de-icers in the winter. US IPA suppliers include ExxonMobil, Dow Chemical, LyondellBasell, Monument Chemical and Shell Chemical.

    Ethanol Plants Seek Rule Changes To Resupply Hand Sanitizer
    By David Pitt Associated Press March 26, 2020

    Hospitals and nursing homes are desperately searching for hand sanitizer amid the coronavirus outbreak and the ethanol industry is ready to step in to provide the alcohol, a key ingredient.

    DES MOINES, Iowa -- As hospitals and nursing homes desperately search for hand sanitizer amid the coronavirus outbreak, federal regulators are preventing ethanol producers from providing millions of gallons of alcohol that could be transformed into the germ-killing mixture. The U.S. Food and Drug Administration's roadblock has been frustrating the health care and ethanol industries, which have been calling for a relaxed regulation to deal with the public health care emergency. “Hand sanitizer is a big part of our lives,” said Eric Barber, CEO of Mary Lanning Healthcare, a hospital in Hastings, Nebraska. “We can’t get any. We order it and it’s just not available.” The problem for the ethanol industry is that most plants make food-grade ethanol, one step below the highest pharmaceutical grade. But since the plants aren't certified to comply with stringent production standards designed to protect quality of medicines, food ingredients and dietary supplements, the FDA doesn't want the alcohol used for a product to be applied to the skin. In addition, the alcohol is not denatured or mixed with a bitter additive to make it undrinkable. The FDA insists this step is “critical” because of cases of poisoning, sometimes fatal, among young children who have accidentally ingested hand sanitizers. An FDA spokesman said Thursday that regulators have already seen a rise in poisonings linked to hand sanitizers in recent weeks, “heightening this public concern.” The FDA is also skeptical of industry claims that undenatured sanitizers could be distributed in a way that would keep them away from children. “It is unclear what, if any, measure could be instituted to ensure that the product does not make its way into consumer hands, where children could have access,” FDA’s Jeremy Kahn said in an emailed statement. Facing a nationwide shortage, Barber said the FDA should temporarily relax regulations to allow alternative production. “You’re talking about alcohol. Does it matter if it's fuel grade or whatever the stuff is they’re trying to price gouge now? I think its common sense,” he said. “We may need to consider a range of possible solutions that were not on the table before the pandemic,” said Nancy Foster, a vice president with the group, in an emailed statement to the AP. The Consumer Brands Association, formerly the Grocery Manufacturers Association, has had conversations with the FDA to push the agency to reconsider its guidelines. The group, which represents branded food, consumer products and beverage companies, said that hand sanitizer supplies are running so low that its members have had to ration it out to workers in stores, distribution centers and manufacturing plants. "We need a temporary solution," said Mike Gruber, vice president of regulatory and technical affairs at the trade association. “This goes toward ensuring basic food safety practices.” Distillers that produce vodka, whisky and other alcoholic drinks have been given some regulatory waivers by the Alcohol and Tobacco Tax and Trade Bureau allowing them to produce hand sanitizer. Many have done that, but they produce much smaller volumes of alcohol than an ethanol plant could produce. They also receive a benefit in the Senate-passed stimulus bill. The Distilled Spirits Council of the United States, which represents dozens of large and small distillers, applauded Congress for easing taxes on distillers who make hand sanitizer. Under the stimulus package passed late Wednesday, distillers don’t have to pay federal excise taxes on alcohol used for hand sanitizer through Jan. 1, 2021. “Hundreds of U.S. distillers are stepping up to produce hand sanitizer and they should not be hit with a huge tax bill for producing this much-needed item, especially at a time when so many of them are struggling,” said Chris Swonger, the group’s president and CEO. But the council said it’s urging the FDA to update its guidance and let distillers use undenatured alcohol for hand sanitizer. The stimulus bill requires distillers to follow the FDA’s guidance if they want to receive the tax breaks. The FDA has waived dozens of regulations in recent weeks to boost production of key medical supplies, including coronavirus tests, ventilators, gloves and hand sanitizers. Under the latest FDA guidelines, regulators maintain standards for alcohol, requiring new producers to use alcohol that meets federal or international standards for use in either drugs or food products. The regulatory hurdles are especially frustrating for Midwest ethanol producers who are facing plunging fuel demand and a petroleum fight between Saudi Arabia and Russia that caused prices to plummet. The factors are forcing more plants to curtail production and close. For ethanol producers relaxed rules, including a requirement of the hard-to-acquire denaturant, would allow them to step in an help in a national emergency. “If we could get the FDA to say yes you can use the beverage grade and for the duration of this emergency at least for some point in time here for the next two weeks you can waive the denaturant we would literally have millions of gallons of hand sanitizer available within a matter of days,” said Monte Shaw, CEO of Iowa Renewable Fuels Association, an ethanol trade group. “Every one of our plants has gotten contacted by people who want this stuff and we can’t send it to them.” Andrew Vrbas owner of Pacha Soap, a boutique soap shop in Hastings, Nebraska, had just finished renovating a 100,000-square-foot former bread factory as a project to boost the community. Now, he’s preparing to set up hand sanitizer production there to supply to hospitals. He’s received calls from hospitals in Nebraska, Florida and New York City seeking hand sanitizer. “We are literally three miles from a plant that has as much ethanol as you could imagine,” he said. “We’re sitting on millions of gallons of alcohol. If we could rally the federal government to say look if you just let us work with local ethanol producers we have the expertise, we have the ability to provide hand sanitizer to hospitals not only in Nebraska but all across the country that are just reaching out through my network saying if you could send us hand sanitizer, we’re out.”

    Virus Inactivation Mechanisms: Impact of Disinfectants on Virus Function and Structural Integrity

    Oxidative processes are often harnessed as tools for pathogen disinfection. Although the pathways responsible for bacterial inactivation with various biocides are fairly well understood, virus inactivation mechanisms are often contradictory or equivocal. In this study, we provide a quantitative analysis of the total damage incurred by a model virus (bacteriophage MS2) upon inactivation induced by five common virucidal agents (heat, UV, hypochlorous acid, singlet oxygen, and chlorine dioxide). Each treatment targets one or more virus functions to achieve inactivation: UV, singlet oxygen, and hypochlorous acid treatments generally render the genome nonreplicable, whereas chlorine dioxide and heat inhibit host-cell recognition/binding. Using a combination of quantitative analytical tools, we identified unique patterns of molecular level modifications in the virus proteins or genome that lead to the inhibition of these functions and eventually inactivation. UV and chlorine treatments, for example, cause site-specific capsid protein backbone cleavage that inhibits viral genome injection into the host cell. Combined, these results will aid in developing better methods for combating waterborne and foodborne viral pathogens and further our understanding of the adaptive changes viruses undergo in response to natural and anthropogenic stressors. Read more here.

    Inactivation Of Influenza Virus By Mild Antiseptics 

    A number of antiseptics were tested for their inactivating effect upon the virus of influenza during a brief period of exposure. This was accomplished by preparing mixtures of the antiseptics and virus, allowing them to remain in contact for 3 minutes, diluting the mixtures to the point where they would not be toxic for chick embryos and then injecting the material into embryonated eggs. Survival of the embryos indicated inactivation of the virus. The following preparations were found to inactivate the virus in 3 minutes or less: phenol, 3 per cent; tincture of iodine, U.S.P. XII, 0.1 per cent; Lugol's solution, U.S.P. XII, 1 per cent; mercuric chloride, 1:1000; potassium permanganate, 1:1000; copper sulfate, 1 per cent; propylene glycol, 90 per cent; liquor antisepticus, N.F. VII, 80 per cent. Read more here.

     

    Antiviral Activity Of Lugol's Solution (Lugol's Iodine) 

    Lugol's Iodine, also known as aqueous iodine and strong iodine solution, is a solution of potassium iodide with iodine in water. Iodine products and Lugol's Iodine are sold online at LabAlley.com. Cleaning with iodine may stop the spread of virusesJean Guillaume Auguste Lugol (18 August 1786 – 16 September 1851) was a French physician. It has been know for a long time that iodine kills viruses. Povidone iodine has been used in hospitals under the brand name Betadine. BETADINE® is used for upper respiratory tract infection care.

    What Inhibits And Inactivates Viruses?

    What Does Not Kill The Coronavirus

    DIY Hand Sanitizers, Face Masks And Disinfecting Sprays | DIY Alternatives for When Stores Are Out of Coronavirus-Fighting Products
    April 4, 2020

    DIY hand sanitizers were the index species in the current wave of shelf extinctions, with usually plentiful supplies of Purell gel and similar products vanishing fast. Even without sanitizers, epidemiologists stress there is an exceedingly reliable alternative that works just as well: wash your hands with soap and water. Read more here.

    CleanSmart Disinfectant Spray Mist Kills 99.9% Of Viruses, Bacteria, Germs, Mold And Fungus

    CleanSmart Disinfectant Spray Mist leaves no chemical residue and is great to clean and sanitize CPAP masks and parts. Simply spray, no rinsing, no wiping, air dry. Safe for food contact on counters and all appliances. Free of alcohol, ammonia, bleach, fragrances and dyes. 100% safe to spray and store around children and it breaks down to saline after use. Read more here.

    Chemical Disinfection Of Virus‐Contaminated Surfaces

    Chemical disinfection is widely practiced as a means of controlling and preventing the spread of infectious diseases. Although disinfection of bacteria has been widely studied, much less attention has been paid to the virucidal potential of commonly used disinfectants in spite of the low infective dose of many human pathogenic viruses. This review considers what is known about the disinfection of viruses and the virucidal properties of different classes of disinfectant chemicals. It focuses on virus disinfection from a practical viewpoint and also critically evaluates the testing techniques currently used for examining the efficacy of disinfectant products. Read more here.

    Factors In The Selection Of Surface Disinfectants For Use In A Laboratory Animal Setting

    Because surface disinfectants are an important means of pathogen control within laboratory animal facilities, these products must have an appropriate spectrum of antimicrobial activity. However, many other factors must also be considered, including effects on human health, environmental safety, and animal behavior. Aqueous solutions of sodium hypochlorite often are considered to be the ‘gold standard’ for surface disinfection, but these products can be corrosive, caustic, and aversive in odor. Read more here.