Polyethylene Glycol (PEG) 400 Food Grade (FCC)

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1 Liter
Sale price $38.00


380 - 420

Polyethylene Glycol (PEG) is a petroleum derived polymer and an oligomer of the polymer of ethylene oxide. Polyethylene glycol is a water-soluble liquid or waxy solid that is used in cosmetics, medicines, emulsification, lubricants, and wetting agents. It appears as a colorless, oily liquid with a faint odor and a pleasant flavor. Due to the high purity of Polyethylene Glycol 400, it is certified by the United States Pharmacopeia (USP) grade and the Food Chemicals Codex (FCC) grade. Lab Alley is selling its premium quality Polyethylene Glycol 400, FCC Grade in the USA, and highly recommends to use it in food processing, medicines, and drugs.

Polyethylene Glycol 400 | USP Grade | PEG 400 FCC (Food) Grade | NF Grade | Used For Toothpaste, Skin, Wax | Clear, Colorless, Viscous Liquid | For Foods, Cosmetics & Pharmaceuticals | CAS # 25322-68-3 | Thinning Agent & Solvent

Product Summary

Polyethylene Glycol 400 | FCC Grade | PEG 400 Food Grade | NF Grade | Used For Toothpaste, Skin, Wax | Clear, Colorless, Viscous Liquid | For Food Processing, Cosmetic Manufacturing, Pharmaceutical Formulations | CAS # 25322-68-3 | Thinning Agent, Solvent/ Solubilizing Agent | Formula C2nH4n+2On+1,n=8.2to9.1 | Low-Molecular-Weight Grade of 400 | Average Molecular Weight Is 400 | Clear, Colorless, Viscous Liquid | Low Toxicity

Lab Alley, based in Austin, Texas is a nationwide supplier of Polyethylene Glycol 400 (PEG 400), Polyethylene Glycol 4000 (PEG 4000) and Polyethylene Glycol 8000 (PEG 8000).

About PEG 400

PEG 400 (polyethylene glycol 400) is a low-molecular-weight grade of polyethylene glycol.  PEG 400 is a clear, viscous, colourless or almost colourless hygroscopic liquid

PEG 400 gets it's name because 400 is the molecular weight. It is a clear, colorless, viscous liquid. Due in part to its low toxicity, PEG 400 is widely used in a variety of pharmaceutical formulations.  PEG 400 is soluble in water, acetone, alcohols, benzene, glycerin, glycols, and aromatic hydrocarbons, and is slightly soluble in aliphatic hydrocarbons.  Within the pharmaceutical industry, PEG 400 is used as a solvent, plasticizer, and a surfactant to lower the surface tension of water.  Polyethylene Glycol 400 molecular weight has been shown to eliminate static and not influence physical properties or part performance of plastic pellets and granules. The cost is minimal; it is highly effective and is readily available from Lab Alley.  Polyethylene Glycol (PEG) is an eco-friendly solvent.

Polyethylene glycol aqueous solution (PEGs), an environmentally friendly solvent was used, for the first time, to develop an extraction method for crude polysaccharides from pericarpium granati with ultrasonic-microwave-assisted extraction (UMAE). Compared with other extraction solvents, PEGs, especially PEG 400, displayed a higher extraction yield.

About Polyethylene Glycol

Polyethylene glycol is a polyether compound with many applications, from industrial manufacturing to medicine. PEG is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight. For Polyethylene uses, click here. PEG 400 is used as a moisturizer and solvent.

Commercial Uses Of Polyethylene Glycol

PEG is the basis of many skin creams (as cetomacrogol) and personal lubricants (frequently combined with glycerin). PEG is used in a number of toothpastes as a dispersant. In this application, it binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste. PEG is also under investigation for use in body armor, and in tattoos to monitor diabetes. In low-molecular-weight formulations (e.g. PEG 400), it is used in Hewlett-Packard design jet printers as an ink solvent and lubricant for the print heads. PEG is also used as an anti-foaming agent in food and drinks – its INS number is 1521 or E1521 in the EU.

Medical Uses Of Polyethylene Glycol

PEG is the basis of a number of laxatives. Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy.  PEG is also used as an excipient in many pharmaceutical products. When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood. 

Integration of PEG 400 into a self-nanoemulsifying drug delivery system improves drug loading capacity and nasal mucosa permeability and prolongs the survival of rats with malignant brain tumors.

Health Effects Of Polyethylene Glycol

When PEG is chemically attached to therapeutic molecules (such as protein drugs or nanoparticles), it can sometimes be antigenic, stimulating an anti-PEG antibody response in some patients. This effect has only been shown for a few of the many available PEGylated therapeutics, but it has significant effects on clinical outcomes of affected patients. Other than these few instances where patients have anti-PEG immune responses, it is generally considered to be a safe component of drug formulations.

What is NF Grade Polyethylene Glycol (PEG) 400?
NF Grade means that a product meets all of the requirements as contained in the NF monograph for that product and is produced in a cGMP compliant facility. If there is no NF monograph, a material cannot be labeled as NF Grade.


Polyethylene Glycol 400, FCC Grade Features:

Average molecular weight 380 - 420
Completeness and color of solution Passes Test
Actual viscosity @ 98.9±0.3°C (210°F) 6.8 - 8.0cst
pH of a 5% solution @ 25°C 4.5 - 7.5
Residue after Ignition 0.1% max.
Heavy Metals 5ppm max
Free Ethylene Oxide 10 ppm max
Free 1,4-Dioxane 510 ppm max
Ethylene glycol &and Diethylene glycol 0.25 max
Organic Volatile Impurities Passes Test
Identification Passes Test
Common Uses
  • Solvent
  • Thinning agent
Commercial/Industrial Applications
  • Toothpastes
  • Skincare products
  • Food processing
Safety and Handling


GRAS Reference Citation 21 CFR 172.820.

Warnings, Safety And Hazards: Inhalation of vapor is not hazardous. Ingestion causes stupor or coma, sometimes leading to fatal kidney injury.  This chemical is combustible.

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