Buy Mannitol Powder ACS Reagent Grade $64+ Bulk Sizes

Mannitol Powder ACS Reagent Grade

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Mannitol Reagent ACS, 500g
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Mannitol Reagent ACS, 2.5kg
Mannitol Reagent ACS, 3kg
Mannitol Reagent ACS, 10kg

Mannitol, also known as D-mannitol, Mannite, and Osmitrol, has the chemical formula C6H14O6. It appears as a white crystalline powder or free-flowing granules with no odor. It possesses a sweet taste and is slightly soluble in Water at ambient conditions. It is produced on a commercial scale by the catalytic or electrolytic reduction of certain monosaccharides such as Mannose and Glucose. The ACS grade is generally equivalent to the reagent grade and is acceptable for use in analytical applications and research laboratories. Lab Alley’s premium quality Mannitol, ACS Reagent Grade complies with the American Chemical Society (ACS) and is highly recommended for achieving reliable and repeatable results in research/biochemical labs. In the United States of America (USA), Lab Alley is selling its high- quality Mannitol, ACS Reagent Grade online at

Mannitol Powder Product Summary

  • Buy Mannitol Powder Online From
  • Ultra Pure Mannitol Powder For Sale Online In The United States | 100%
  • Fast Shipping Of Mannitol Powder For U.S. Based Customers
  • Order Mannitol Powder In Bulk At Wholesale Prices
  • Formula C6H14O6
  • CAS # 64-65-8
  • Used: For Parkinson's Disease, Sugar Alcohol And Sweetener, For Glaucoma, Medical Uses, Food Uses, For Analytical Chemistry

About Mannitol Powder

Mannitol is a type of carbohydrate called a sugar alcohol, or polyol. Mannitol contains about 60 percent fewer calories than sugar and is half as sweet. Mannitol occurs naturally in fresh mushrooms, brown algae, tree bark and most fruits and vegetables.

Mannitol can be used to form a complex with boric acid. This increases the acid strength of the boric acid, permitting better precision in volumetric analysis of this acid.

D-mannitol is the D-enantiomer of mannitol. It has a role as an osmotic diuretic, a sweetening agent, an antiglaucoma drug, a metabolite, an allergen, a hapten, a food bulking agent, a food anticaking agent, a food humectant, a food stabiliser, a food thickening agent, an Escherichia coli metabolite and a member of compatible osmolytes.

Mannitol is an osmotic agent and a free radical scavenger. It acts by drawing fluid out of tissue into the vascular compartment. It also reduces blood viscosity and hence increases cerebral blood flow, which results in an autoregulatory vasoconstriction that may reduce ICP.

Clinical Trials

Randomized clinical trial comparing sodium picosulfate with mannitol on the preparation FOR colonoscopy in hospitalized patients. The cleansing of the colon for a colonoscopy exam must be complete so as to allow the visualization and inspection of the intestinal lumen. The ideal cleansing agent should be easily administered, have a low cost, and minimum collateral effects. Sodium picosulfate together with the magnesium citrate is a cathartic stimulant and mannitol is an osmotic laxative, both usually used for this purpose.

Effective and safe mannitol administration in patients undergoing supratentorial tumor surgery: A prospective, randomized and double blind study.  Although osmotic diuresis with mannitol is commonly used to provide brain relaxation, there is no consensus regarding its optimal dose and combination with loop diuretics. The aim of the present study is to evaluate the effects of mannitol and combination of furosemide with different doses of mannitol on brain relaxation and on blood electrolytes, lactate level, urine output, fluid balance and blood osmolarity in patients undergoing supratentorial tumor surgery.

Safety, Tolerability and Effects of Mannitol in Parkinson's Disease (PD-mannitol)

Parkinson's disease is a progressive neurodegenerative disease that causes disabling motor and cognitive impairments. Currently, no disease-modifying therapy exists for this disease. Mannitol, a naturally-occurring substance, which is commonly used as sweetener, was offered as such agent. In this phase II, safety, tolerability-based dose finding, and efficacy study, mannitol or placebo (dextrose) in escalating doses will be given to patients with Parkinson's disease for 36 weeks.


Mannitol Reagent ACS Features:

Assay 99.2%
Specific Rotation, [a]2D5 +24.1
Melting Point 166C
Loss on Drying 0.05%
Reducing Sugars Pass
Residue after Ignition 0.01%
Titrable Acids 0.0008 meq/g
Chloride <1 ppm
Sulfate <1 ppm
Lead <0.5 ppm
Nickel <1 ppm
Common Uses
  • Reagent
  • Chemical precursor
Commercial/Industrial Applications
  • Inert osmotic control
  • Biological studies
Safety and Handling

Mannitol’s safety has been reviewed and confirmed by health authorities around the world, including the World Health Organization, the European Union, and the countries Australia, Canada and Japan. The U.S. Food and Drug Administration (FDA) also recognizes mannitol as safe.  

Symptoms of exposure to Mannitol include nausea, vomiting, headache, chills, chest pain and pulmonary edema. It may cause irritation of the skin, eyes and respiratory tract. Other symptoms may include lethargy, confusion, heart failure and death. Exposure has caused an electrolyte and fluid imbalance, hypersensitivity reactions, diarrhea, thirst, fever, tachycardia, hyponatremia, urinary retention, dehydration, blurred vision, convulsions, urticaria, hypotension and hypertension. It has also caused hyperglycemia and glycosuria. Coughing may result from inhalation. Ingestion may cause gastric irritation. Skin contact may cause discoloration of sensitive skin. Eye contact may cause redness and pain. Intravenous use has led to blood pressure elevation and bladder tubule changes. ACUTE/CHRONIC HAZARDS: This compound may cause irritation of the skin, eyes and respiratory tract. When heated to decomposition it emits acrid smoke and toxic fumes of carbon monoxide and carbon dioxide.

Please contact us to request a Safety Data Sheet (SDS) and Certificate of Analysis (COA) for Mannitol Reagent ACS.

Download Product Specification Sheet
Product Ordering Options, Prices, Bulk Sizes & Shipping

You can buy Mannitol Powder ACS Reagent Grade for $64 online, locally or call 512-668-9918 to order bulk sizes. Your packages will be shipped in 1-2 business days via UPS or LTL. Lab Alley Brand Mannitol Powder ACS Reagent Grade is for sale in bulk sizes and is in stock. Handy individual consumer size containers for DIY projects are leak resistant. This high quality compound is made in America. It is a high purity chemical substance that is ideally suited for scientific, development, analytical, clinical, medical, research and testing applications. Mannitol Powder ACS Reagent Grade is delivered quickly to laboratories, factories and businesses in safe chemical resistant containers. 

Manufacturing size drums, IBC totes, pallet loads and bulk industrial production scale quantities are shipped from Lab Alley's U.S.-based distribution centers by LTL freight carriers. Request a discounted wholesale price quote, here. Read customer and product reviews, here. Read return and refund policies, here. Lab Alley, founded in 2013, is a reliable Mannitol Powder ACS Reagent Grade supplier and distributor headquartered near Austin, Texas. Lab Alley was a 2021 Inc. 5000 honoree. Email if you have questions about buying Mannitol Powder ACS Reagent Grade. 

Download the Mannitol Powder ACS Reagent Grade MSDS/SDS to get safety tips and health hazard information. Mannitol Powder ACS Reagent Grade should be carefully handled, stored in a cool dry place and chemical waste should be disposed of properly and safely.

Mannitol Powder ACS Reagent Grade Retail Prices, Package Sizes And Bulk Quantity Ordering Options: 500g $64, 1kg $112, 2.5kg $251, 3kg $361, 10kg $693.

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