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About Dimethylformamide (N,N-Dimethylformamide)
Dimethylformamide is an organic compound with the formula (CH3)2NC(O)H. Commonly abbreviated as DMF (although this initialism is sometimes used for dimethylfuran, or dimethyl fumarate), this colorless liquid is miscible with water and the majority of organic liquids. DMF is a common solvent for chemical reactions.
Dimethylformamide (DMF) is a clear, colorless, hygroscopic liquid with a slight amine odor.
DMF is a polar organic solvent that is widely used in the synthesis of organic compounds. The high solvent power and stability of DMF at elevated temperatures contribute to its utility. DMF is a solvent for vinyl resins, acetylene, butadiene, and polyacrylic fibers. It is also a catalyst in carboxylation reactions.
Dimethylformamide Uses
N,N-Dimethylformamide is a colorless, odorless water-miscible liquid solvent used in the production of acrylic fibers, plastics, pesticides, and synthetic leather. It is also used in the manufacture of paint, film, and adhesives.
Dimethylformamide is primarily used as an industrial solvent. Dimethylformamide solutions are used to process polymer fibers, films, and surface coatings; to permit easy spinning of acrylic fibers; to produce wire enamels, and as a crystallization medium in the pharmaceutical industry.
The primary use of DMF is as a solvent with low evaporation rate. DMF is used in the production of acrylic fibers and plastics. It is also used as a solvent in peptide coupling for pharmaceuticals, in the development and production of pesticides, and in the manufacture of adhesives, synthetic leathers, fibers, films, and surface coatings.
Dimethylformamide Properties
- CAS Number: 68-12-2
- Boiling point: 307.4°F (153°C)
- Density: 944 kg/m³
- Molar mass: 73.09 g/mol
- Melting point: -77.8°F (-61°C)
- Formula: C3H7NO
- IUPAC ID: N,N-Dimethylmethanamide
- Viscosity: 0.92 mPa s
Dimethylformamide Safety
DMF is readily absorbed through the skin, inhaled, or ingested. DMF is a potent liver toxin. DMF may cause abdominal pain, constipation, nausea and vomiting, headache, weakness, dizziness, skin problems, and alcohol intolerance.
Download Dimethylformamide SDSs (MSDS)
Dimethylformamide Storage
Store Dimethylformamide at room temperature and avoid prolonged exposure to light.
As DMF can attack certain metals and compounds, such as copper and aluminum, plastics, rubbers, and coatings, it should be stored in mild-steel containers.
It should be stored under fire-proof conditions and away from oxidizing agents, halogens, alkylaluminium, and halogenated hydrocarbons.
Dimethylformamide Toxicity
DMF is readily absorbed through the skin, inhaled, or ingested. DMF is a potent liver toxin. DMF may cause abdominal pain, constipation, nausea and vomiting, headache, weakness, dizziness, skin problems, and alcohol intolerance.
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