Phenol, also known as Carbolic Acid, Hydroxybenzene, Phenylic Acid, has the chemical formula C6H6O. Phenol Crystals appear as hygroscopic colorless-to-white crystalline solid with a sweet odor. It evaporates more slowly than water and is slightly soluble in Water at ambient conditions. In the United States of America (USA) phenol is widely synthesized by the oxidation of cumene, yielding acetone as a by-product. The ACS grade is generally equivalent to the reagent grade and is acceptable for use in analytical applications and research laboratories. Lab Alley’s premium quality Phenol, ACS Reagent Grade complies with the American Chemical Society (ACS) and is highly recommend for achieving reliable and repeatable results in research/biochemical labs. In the United States of America (USA), Lab Alley is selling its high-quality Phenol, ACS Reagent Grade online at laballey.com.
Phenol is a transparent crystalline solid. Phenolics are active ingredients in some household disinfectants. Phenolic compounds, have been studied extensively (biologically and chemically) due to their extensive antiviral activities. Learn about the cytotoxic, antiviral properties and anti-HSV-1 activities of phenolic compounds here. They are also found in some mouthwashes and in disinfectant soap and handwashes. Phenol is probably the oldest known disinfectant as it was first used by Joseph Lister (pioneer of antiseptic surgery), when it was called carbolic acid.
Phenol is also called carbolic acid, hydroxybenzene, oxybenzene, phenylic acid. a white, crystalline, water-soluble, poisonous mass, C6H5OH, obtained from coal tar, or a hydroxyl derivative of benzene: used chiefly as a disinfectant, as an antiseptic, and in organic synthesis.
Phenols are widely used in household products and as intermediates for industrial synthesis. For example, phenol itself is used (in low concentrations) as a disinfectant in household cleaners and in mouthwash. Phenol may have been the first surgical antiseptic. Read more here.
Phenol is an aromatic organic compound with the molecular formula C6H5OH. It is a white crystalline solid that is volatile. The molecule consists of a phenyl group (−C6H5) bonded to a hydroxy group (−OH). Mildly acidic, it requires careful handling because it can cause chemical burns. Read more here.
About Phenol Liquid
Phenol liquid is often used in molecular biology with trichloromethane and chloroform to separate RNA, DNA, or proteins, and isolate them in the pure form. This process is known as liquid-liquid extraction. Phenol extraction is a processing technology used to prepare phenols as raw materials, compounds or additives for industrial wood processing and for chemical industries. Phenol extraction also is a laboratory process to purify DNA samples.
About Phenol Crystals
Phenol crystals are used to describe the solid forms that result from the phenol compound, which is also known as the carbolic acid. It is an organic compound that has the molecular structure of C6H5OH. It is an extremely volatile white crystalline solid that is mildly acidic.
Phenol is an aromatic organic compound with the molecular formula C₆H₅OH. It is a white crystalline solid that is volatile. The molecule consists of a phenyl group bonded to a hydroxy group. Mildly acidic, it requires careful handling because it can cause chemical burns.
Chemical Properties Of Phenols And Reference Resources
- Phenol CAS Registry Number: 108-95-2
- Phenol Molar Mass: 94.11 g/mol
- Phenol Formula: C6H5OH
- Phenol Boiling Point: 359.1°F (181.7°C)
- Phenol Melting Point: 104.9°F (40.5°C)
- Phenol Density: 1.07 g/cm³
- Phenol Is Soluble In: Water
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Phenolics are active ingredients in some household disinfectants. They are also found in some mouthwashes and in disinfectant soap and handwashes. Phenol (carbolic acid) is one of the oldest antiseptic agents. Phenols are used as antiviral agents in the treatment of HIV. Phenol has good penetrating power into organic matter and is mainly used for disinfection of equipment or organic materials that are to be destroyed (eg, infected food and excreta).
Evaluation Of Antiviral Activity Of Phenolic Compounds And Derivatives Against Rabies Virus
Phenolic compounds are derived from the secondary plant metabolism, although they can also be obtained by synthetic processes. Many studies have shown a great range of pharmacological effects for these substances, including vasodilatation, antiallergenic, antiinflammatory and antiviral properties, among others. Read more here.
Phenolic disinfectants (e.g. Meytol, Dettol, etc.) are widely used for domestic purposes. Instructions on the bottles are clearly given with regards to the dilutions that should be used. In domestic cleaning, these instructions are often ignored and higher concentrations are used with the thinking that 'the more I pour, the cleaner it gets!'. Furthermore, cleaning equipment is sometimes stored without prior rinsing with fresh water. As water evaporates much faster than phenol, the solution on stored mops/ brushes, etc. becomes progressively more and more concentrated and can cause chemical burns when these utensils are handled at a later time. We therefore suggest that two further instructions should be added to the usual instructions on bottles of household phenolic disinfectants, namely: 'wear gloves when performing domestic cleaning' and 'wash all cleaning equipment with plenty of fresh water after use'. We support this by a case report of a 65-year-old man who sustained full-thickness, painless chemical burns to his right hand after handling a moist mop which had been used for cleaning a carpet with a phenolic household disinfectant solution 2 days earlier. Read more here.
Natural phenolic compounds play an important role in cancer prevention and treatment. Phenolic compounds from medicinal herbs and dietary plants include phenolic acids, flavonoids, tannins, stilbenes, curcuminoids, coumarins, lignans, quinones, and others. Various bioactivities of phenolic compounds are responsible for their chemopreventive properties (e.g., antioxidant, anticarcinogenic, or antimutagenic and anti-inflammatory effects) and also contribute to their inducing apoptosis by arresting cell cycle, regulating carcinogen metabolism and ontogenesis expression, inhibiting DNA binding and cell adhesion, migration, proliferation or differentiation, and blocking signaling pathways. This review covers the most recent literature to summarize structural categories and molecular anticancer mechanisms of phenolic compounds from medicinal herbs and dietary plants. Read more here.
Phenolic compounds are a class of the most widely distributed secondary metabolites in plants. They may function as pollination, pigment constituents and protection against UV radiation and predation for plants. Plant phenols have been studied for hundreds of years, and have acted as the major class of compounds that show great activity against various viruses such as herpes simplex, Epstein-Barr virus, equid herpesvirus, hepatitis B virus, human immunodeficiency virus, respiratory syncytial and canine distemper viruses. Because of the extensive antiviral activities, phenolic compounds have been widely investigated both chemically and biologically. The distribution of hydroxyl groups and ester group accounts for different antiviral activities of phenolic compounds, and research of these compounds has revealed that phenols have great potential for the development as therapeutic agents against various viruses. As a result, dozens of phenols in functional foods have been discovered to display antiviral activity.
Objective: This review emphasizes structure classification and antiviral activities of plant phenolic compounds, which are expected to provide guides for rational design of antiviral drugs. Read more here.
This volume is concerned throughout with the question of whether or not there is a regulatory role of phenolic compounds in the metabolism of plants and animals. Several such compounds are well known as hormonal mediators of metabolic events in animals; in plants, however, the metabolic roles of phenolic compounds are less well defined. As presented here-we believe for the first time this area of metabolic control is considered on a comparative basis. The similarities and differences between plant and animal systems in their phenolic constituents and in their metabolic responses to the presence of phenolics are discussed, together with a discussion of some pathological metabolic pathways. The contributors, in their consideration of physiological relationships, were invited to speculate as well as to present estab lished data. Emphasis has been placed on the critical review and appraisal of the considered topics rather than a mere presentation of extensive individual experimental results. Read more here.
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- Biological testing
- Chemical intermediate
- Cosmetics industry
- Antimicrobial antiseptics
- Food applications
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DOT: Phenol, solid, 6.1, UN1671, PG II
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