A number of antiseptics were tested for their inactivating effect upon the virus of influenza during a brief period of exposure. This was accomplished by preparing mixtures of the antiseptics and virus, allowing them to remain in contact for 3 minutes, diluting the mixtures to the point where they would not be toxic for chick embryos and then injecting the material into embryonated eggs. Survival of the embryos indicated inactivation of the virus. The following preparations were found to inactivate the virus in 3 minutes or less: phenol, 3 per cent; tincture of iodine, U.S.P. XII, 0.1 per cent; Lugol's solution, U.S.P. XII, 1 per cent; mercuric chloride, 1:1000; potassium permanganate, 1:1000; copper sulfate, 1 per cent; propylene glycol, 90 per cent; liquor antisepticus, N.F. VII, 80 per cent. Read more here. Buy virus disinfectants here.
This process, developed by the New York Blood Center, is the most widely used viral inactivation method to date. It is predominantly used in the blood plasma industry, by over 50 organizations worldwide and by the American Red Cross. This process is only effective for viruses enveloped in a lipid coat, however. The detergents used in this method interrupt the interactions between the molecules in the virus's lipid coating. Most enveloped viruses cannot exist without their lipid coating so are destroyed when exposed to these detergents. Other viruses may not be destroyed but they are unable to reproduce rendering them non-infective. The solvent creates an environment in which the aggregation reaction between the lipid coat and the detergent happen more rapidly. The detergent typically used is Triton X-100, which is made with Polyethylene glycol (PEG), an eco-friendly solvent.